Photo by William Buchheit

Popular airlines from Chicago O'Hare Intl. Airport (ORD) to Greenville-Spartanburg Intl. Airport (GSP)
- American Airlines
American Airlines
- Delta
Delta
- United
United
- Southwest Airlines
Southwest Airlines
- Plan, book, fly with confidence
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Cheap flights from Chicago to Greenville (ORD-GSP)
Prices were available within the past 7 days and start at €93 for one-way flights and €178 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€178 Return, found 5 days ago
€178
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€207 Return, found 5 days ago
€207
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€213 Return, found 5 days ago
€213
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€216 Return, found 5 days ago
€216
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€217 Return, found 5 days ago
€217
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€221 Return, found 5 days ago
€221
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€232 Return, found 5 days ago
€232
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€239 Return, found 5 days ago
€239
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€246 Return, found 5 days ago
€246
Return
found 5 days ago

Sat, 6 Sep - Mon, 8 Sep
ORD
Chicago
GSP
Greenville
€247 Return, found 5 days ago
€247
Return
found 5 days ago
Find the cheapest month to fly from Chicago (ORD) to Greenville (GSP)
October is typically the cheapest month to fly
From €159 - €371 per traveller.
Graph displaying average flight prices per month
Origin airport | O'Hare Intl. |
Destination airport | Greenville-Spartanburg Intl. |
Return price | €177 |
Distance | 924 km |
Average flight time | 2 hours 59 mins |
Perfect flights from Chicago to Greenville
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Chicago to Greenville. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible O'Hare Intl. to Greenville-Spartanburg Intl. ticket options cater to your travel preferences, with incredible one-way fares from €93 and roundtrip prices from €178. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at Greenville-Spartanburg Intl. and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Greenville.
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Top Routes from Chicago
- Chicago to Newark Liberty Intl. Airport (ORD - EWR)
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Top Routes to Greenville
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