4 Star Hotels in Southeastern Indiana, United States of America

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Check availability on Southeastern Indiana 4 Star Hotels

Tonight
1 Dec - 2 Dec
Tomorrow
2 Dec - 3 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Southeastern Indiana 4 Star Hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3830)
"Great place to stay "
United States
Tia
The price is €95
includes taxes & fees
10 Dec - 11 Dec
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1704)
"Wonderful property and staff. Would love to stay again. "
United States
Hanna
The price is €170
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1098)
"Clean, hotel was amazing, great breakfast "
United States
Alana
The price is €121
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites Louisville Downtown
Lobby
The Brown Hotel

The Brown Hotel

4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1144)
"Wonderful hotel with lots of history; clean rooms; Nice lounge and restaurants."
United States
Kim
The price is €120
includes taxes & fees
2 Dec - 3 Dec
The Brown Hotel
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1011)
"Great stay"
United States
Katharine
The price is €137
includes taxes & fees
3 Dec - 4 Dec
Hotel Genevieve part of JdV by Hyatt
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1005)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is €145
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1009)
"Enjoyed our stay "
United States
Jedediah
The price is €119
includes taxes & fees
15 Dec - 16 Dec
Hyatt Regency Louisville
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1015)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is €148
includes taxes & fees
21 Dec - 22 Dec
The Grady
Restaurant
Louisville Marriott Downtown

Louisville Marriott Downtown

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1004)
"Room was great, but the service by the attendant that wait on me was exceptional in what she done for me."
United States
Michael
The price is €174
includes taxes & fees
14 Dec - 15 Dec
Louisville Marriott Downtown
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (427)
"Really a nice place to stay "
United States
Jeanie
The price is €172
includes taxes & fees
14 Dec - 15 Dec
Hotel Distil, Autograph Collection
Exterior
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (50)
"Lovely hotel in downtown Louisville. Well appointed room, comfy bed and outstanding dining. "
United States
Michelle
The price is €146
includes taxes & fees
21 Dec - 22 Dec
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1006)
"This was a lovely stay and we will definitely return. "
United States
Dolorse
The price is €128
includes taxes & fees
22 Dec - 23 Dec
Seelbach Hilton Louisville Downtown
Signature Suite, 1 Queen Bed, Non Smoking
Stellar Suites

Stellar Suites

4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (116)
"Clean and great location "
United States
Greg
The price is €163
includes taxes & fees
15 Dec - 16 Dec
Stellar Suites
Deluxe Room, 1 King Bed (Culbertson Suite) | Balcony
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

4.0 star property
New Albany
9.8 out of 10, Exceptional, (646)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
The price is €87
includes taxes & fees
2 Dec - 3 Dec
The Pepin Mansion Historic B&B
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

4.0 star property
Downtown Louisville
8.2 out of 10, Very good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is €173
includes taxes & fees
2 Dec - 3 Dec
CozySuites at Nulu
BBQ/picnic Area
stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville

4.0 star property
Clarksville
9.8 out of 10, Exceptional, (43)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
stayAPT Suites Louisville North-Clarksville
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is €178
includes taxes & fees
2 Dec - 3 Dec
The Reserve on Main
Exterior detail
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Apartment, 3 Bedrooms, Non Smoking | Private kitchen
TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites

4.0 star property
Downtown Louisville
The price is €478
includes taxes & fees
2 Dec - 3 Dec
TWO Stunning Nulu CozySuites
Front of property
Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North

4.5 star property
Jeffersonville
7.4 out of 10, Good, (944)
"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"
United States
alexis
Hawthorn Suites by Wyndham Louisville North
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Learn more about Southeastern Indiana

Explore lots to see and do in Southeastern Indiana—live music, sports teams and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards.

See all hotels in Southeastern Indiana
Belle of Louisville featuring a bay or harbour and a ferry as well as a small group of people

Top Southeastern Indiana Hotel Reviews

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

10/10 Excellent
"Everything was great. Beautiful mansion and beautiful room. Host was very nice and friendly. Already considering a return trip."
Kenneth 1-night trip
Posted 10 days ago
The Pepin Mansion Historic B&B

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You'll find an array of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a guest favourite in this city that offers concierge services and massage services. Another property that gets excellent reviews from travellers is Hyatt Regency Louisville. A swimming pool and concierge services help make it a top choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
Expedia can help you easily track down the ideal 4-star hotel for your holiday in Southeastern Indiana. Use our filter tool to fine-tune your search by things like price, amenities and hotel star rating and get access to fantastic deals in a few clicks.

  • Search for the lowest price from €87

What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
If you decide to book a stay at a 4-star hotel in Southeastern Indiana, you'll usually find plenty of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to excellent service and upmarket surroundings. Choose a 5-star hotel and you'll have access to a few more perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You're likely to get additional amenities and first-rate services at a 5-star stay, but both are terrific options for luxury guests.

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