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5 Star Hotels in São Tomé Island, São Tomé and Príncipe

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Check availability on São Tomé Island 5 Star Hotels

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for São Tomé Island 5-star hotels

Outdoor pool
Pestana São Tomé

Pestana São Tomé

Pestana São Tomé
5.0 star property
Vila Maria
8.0 out of 10, Very good, (78)
"Wonderful stay, great staff, easy, relaxing delightful."
Canada
alexander
The price is €201
includes taxes & fees
23 Dec - 24 Dec
Pestana São Tomé
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in São Tomé Island.
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

Praia Lagarto São Tomé
The price is €215 per night from 4 Jan to 5 Jan
€215
4 Jan - 5 Jan 2026
includes taxes & fees
9.4/10 Exceptional! (62 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about São Tomé Island

Venture to sights like Pico São Tomé and Estadio Nacional 12 de Julho as you discover São Tomé Island.

See all hotels in São Tomé Island
Nice place, good food... Quite difficult to reach, you need a good car...
Photo by Fabrice Récalt
Open Photo by Fabrice Récalt

Top São Tomé Island Hotel Reviews

Pestana São Tomé

Pestana São Tomé

10/10 Excellent
"Wonderful stay, great staff, easy, relaxing delightful."
alexander 5-night trip
Posted 13 days ago
Pestana São Tomé

Frequently asked questions

How much does it cost to stay in a 5-star hotel in São Tomé Island?
The amount you pay for a 5-star hotel in São Tomé Island depends on things such as when you plan to travel and the length of your stay. Our insider tip for scoring the best deal? Use our pricing filters to check out the available hotels for your chosen dates.

  • Search for the lowest price per night from €215

What makes a hotel 5 stars in São Tomé Island?
From fine dining restaurants and 24-hour gyms to pools and dreamy bedding, the 5-star experience in São Tomé Island is all about luxury and comfort. But it calls for more than just upscale perks to earn a 5-star rating. Stays also have to deliver outstanding services like in-room massage treatments, dry cleaning and laundry and room service any time night or day.
Are there any 5-star all-inclusive resorts in São Tomé Island?
Find a luxurious getaway that includes your room, meals, activities and entertainment in São Tomé Island with Expedia's filter tool. Search for resorts rated 5 stars and select the "All inclusive" filter. Double-check what's included in the upfront price. That way, you can take full advantage of all the premium perks from the moment you get there.