5 Star Hotels in Southwestern Ontario, Ontario
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southwestern Ontario 5 Star Hotels
Tonight
15 Sept - 16 SeptTomorrow
16 Sept - 17 SeptThis weekend
18 Sept - 20 SeptNext weekend
25 Sept - 27 SeptOur top choices for Southwestern Ontario 5-star hotels
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southwestern Ontario.
Caesars Windsor Hotel & Casino - A Caesars Rewards Destination
377 Riverside Dr E Windsor ON
€63
14 Oct - 15 Oct
includes taxes & fees
8.8/10 Excellent! (3,491 reviews)
Hard Rock Hotel London Ontario
100 Kellogg Lane London ON
€245
16 Sept - 17 Sept
includes taxes & fees
Crowne Plaza Kitchener-Waterloo by IHG
105 King St E Kitchener ON
€113
24 Sept - 25 Sept
includes taxes & fees
Still don't see what you're looking for?
See all properties in Southwestern Ontario.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southwestern Ontario
Discover hundreds of miles of shorelines, rivers, nature trails, scenic roads and more in this beautiful area sandwiched between Lake Huron and Lake Erie.
See all hotels in Southwestern Ontario
Top Southwestern Ontario Hotel Reviews
Explore a world of travel with Expedia
- 3 Star Hotels in Belwood
- 3 Star Hotels in Downtown London
- 3 Star Hotels in Millbank
- 3 Star Hotels in Minto
- 4 Star Hotels in East Garafraxa
- 4 Star Hotels in Elora Cataract Trailway
- 4 Star Hotels in Goderich
- 5 Star Hotels in Erin
- Arthur Hotels
- Belwood Hotels
- Breslau Hotels
- Cheap Hotels in Cambridge
- Pet Friendly Hotels in Cambridge
- Hotels with Spa in Cambridge
- Cambridge Hotels
- Centre Wellington Hotels
- Hotels near Chicopee Ski and Summer Resort
- Hotels near Church of Our Lady Immaculate
- Hotels near Conrad Centre for the Performing Arts
- Elmira Hotels
- Apartments in Elora
- Apartments in Elora Cataract Trailway
- Residences in Elora Cataract Trailway
- Hotels near Elora Gorge Conservation Area
- Elora Hotels
- Hotels near Elora SkyRider Zipline
- Fergus Hotels
- Granton Hotels
- Guelph Hotels
- Harriston Hotels
- Hilton Hotels in Heidelberg
- Adventure Sport Hotels in Kitchener
- Casino Hotels in Kitchener
- Cheap Hotels in Kitchener
- Romantic Hotels in Kitchener
- Hotels with Spa in Kitchener
- Kitchener Hotels
- Listowel Hotels
- Hotels near McCully's Hill Farm
- Millbank Hotels
- Mitchell Hotels
- Mount Forest Hotels
- Lgbt-Friendly Hotels in New Hamburg
- Hotels with Spa in New Hamburg
- New Hamburg Hotels
- Palmerston Hotels
- Saint Jacobs Hotels
- Ranches in Southern Ontario
- Boutique Hotels in Southwestern Ontario
- Romantic Hotels in Southwestern Ontario
- Hotels near St Jacobs Farmers Market
- Hotels near St. Jacobs Market District Visitor Information Centre
- St. Mary's Hotels
- B&B in Stratford
- Beach Hotels in Stratford
- Stratford Hotels
- Apartments in Waterloo
- Cheap Hotels in Waterloo
- Luxury Hotels in Waterloo
- Hotels with Spa in Waterloo
- Waterloo Hotels
- Hotels near Waterloo Park
- Pet Friendly Hotels in Woodstock
- Woodstock Hotels
- Avon River
- Cambridge Butterfly Conservatory
- Conestoga Mall
- Visit Elora Cataract Trailway
- Elora Gorge Conservation Area
- Elora Holidays
- Visit Elora
- Guelph Holidays
- Louise Marshall Hospital
- Millbank Holidays
- Visit Millbank
- Minto Holidays
- Visit Minto
- Rockway Golf Course
- Stratford Holidays
- Waterloo Visitor & Heritage Information Centre
- Woodstock Holidays
- Car hire Cambridge
- Car hire near Heidelberg
- Car hire near Kitchener
- Car hire Waterloo
- Car hire near Zipline Extreme
- Centauro Rental Cars in Southwestern Ontario
- Global Rent a Car Rental Cars in Southwestern Ontario
- Priceless Car Rental Rental Cars in Southwestern Ontario
- Thrifty Car Rental Rental Cars in Southwestern Ontario