Abilene Hotel Guide - Abilene Regional Medical Center hotels in Abilene, United States of America.

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24 Dec - 25 Dec
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25 Dec - 26 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Abilene Regional Medical Center hotels

Front of property – evening/night
Comfort Inn & Suites Regional Medical Center

Comfort Inn & Suites Regional Medical Center

Comfort Inn & Suites Regional Medical Center
2.5 star property
0.4 km from Abilene Regional Medical Center
8.2 out of 10, Very good, (996)
"Very friendly staff, clean rooms all around positive experience "
United States
Mark
The price is €126
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Regional Medical Center
Lobby
Hilton Garden Inn Abilene

Hilton Garden Inn Abilene

Hilton Garden Inn Abilene
3.0 star property
3 km from Abilene Regional Medical Center
8.6 out of 10, Excellent, (884)
"We enjoyed our stay place was one of the nicest Hilton we’ve stayed in clean and friendly customer service!"
United States
Christopher
The price is €156
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Abilene
Seasonal outdoor pool
Super 8 by Wyndham Abilene South

Super 8 by Wyndham Abilene South

Super 8 by Wyndham Abilene South
2.0 star property
2.6 km from Abilene Regional Medical Center
6.2 out of 10, (1001)
"Yes. Amana was exceptional "
United States
Kay
The price is €77
includes taxes & fees
25 Dec - 26 Dec
Super 8 by Wyndham Abilene South
Terrace/patio
MCM Elegante Suites Abilene

MCM Elegante Suites Abilene

MCM Elegante Suites Abilene
3.0 star property
3.4 km from Abilene Regional Medical Center
9.0 out of 10, Wonderful, (1002)
"Good place to stay. "
United States
Terri
The price is €158
includes taxes & fees
25 Dec - 26 Dec
MCM Elegante Suites Abilene
Property amenity
TownePlace Suites by Marriott Abilene Southwest

TownePlace Suites by Marriott Abilene Southwest

TownePlace Suites by Marriott Abilene Southwest
3.0 star property
4 km from Abilene Regional Medical Center
9.6 out of 10, Exceptional, (301)
"Everything was excellent!!"
United States
Macario
The price is €212
includes taxes & fees
4 Jan - 5 Jan 2026
TownePlace Suites by Marriott Abilene Southwest
Terrace/patio
Home2 Suites by Hilton Abilene Southwest

Home2 Suites by Hilton Abilene Southwest

Home2 Suites by Hilton Abilene Southwest
3.0 star property
4.2 km from Abilene Regional Medical Center
9.4 out of 10, Exceptional, (442)
"Shops nearby, very friendly staff "
United States
yadira
The price is €166
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites by Hilton Abilene Southwest
Exterior
Hampton Inn Abilene

Hampton Inn Abilene

Hampton Inn Abilene
2.5 star property
3.8 km from Abilene Regional Medical Center
8.4 out of 10, Very good, (907)
"Great stop heading east from CA to FL. Clean and accommodating "
United States
Tara
The price is €157
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Abilene
Property amenity
Courtyard by Marriott Abilene Southwest/Abilene Mall South

Courtyard by Marriott Abilene Southwest/Abilene Mall South

Courtyard by Marriott Abilene Southwest/Abilene Mall South
3.0 star property
3.2 km from Abilene Regional Medical Center
8.2 out of 10, Very good, (1001)
"Very clean hotel, nice and friendly staff"
United States
eleazar
The price is €160
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard by Marriott Abilene Southwest/Abilene Mall South
Lobby lounge
Fairfield Inn & Suites Abilene

Fairfield Inn & Suites Abilene

Fairfield Inn & Suites Abilene
2.5 star property
3.7 km from Abilene Regional Medical Center
8.2 out of 10, Very good, (993)
"Friendly staff, clean room, comfortable bed. "
United States
stephanie
The price is €138
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites Abilene
Courtyard
Abilene Whitten Inn

Abilene Whitten Inn

Abilene Whitten Inn
2.5 star property
4.7 km from Abilene Regional Medical Center
8.2 out of 10, Very good, (1004)
"Once again, we're pleased with our atay."
United States
Walter
The price is €116
includes taxes & fees
27 Dec - 28 Dec
Abilene Whitten Inn
Exterior
Holiday Inn Express & Suites Abilene by IHG

Holiday Inn Express & Suites Abilene by IHG

Holiday Inn Express & Suites Abilene by IHG
2.5 star property
5.3 km from Abilene Regional Medical Center
8.4 out of 10, Very good, (954)
"The woman at the front desk was very friendly!"
United States
Bethany
The price is €134
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express & Suites Abilene by IHG
Exterior
Doubletree by Hilton Abilene Downtown Convention Center

Doubletree by Hilton Abilene Downtown Convention Center

Doubletree by Hilton Abilene Downtown Convention Center
4.0 star property
Original Town North, 8.8 km from Abilene Regional Medical Center
9.4 out of 10, Exceptional, (533)
"Fantastic "
United States
Genevieve
The price is €188
includes taxes & fees
2 Jan - 3 Jan 2026
Doubletree by Hilton Abilene Downtown Convention Center
Standard Room, 2 Queen Beds, Non Smoking
Big Country Hotel & Suites, SureStay Collection by BW

Big Country Hotel & Suites, SureStay Collection by BW

Big Country Hotel & Suites, SureStay Collection by BW
2.5 star property
5.5 km from Abilene Regional Medical Center
8.4 out of 10, Very good, (1063)
"Great stay. Friendly staff. "
United States
Andrew
The price is €132
includes taxes & fees
28 Dec - 29 Dec
Big Country Hotel & Suites, SureStay Collection by BW
Reception
Days Inn by Wyndham Abilene

Days Inn by Wyndham Abilene

Days Inn by Wyndham Abilene
2.5 star property
3.8 km from Abilene Regional Medical Center
7.4 out of 10, Good, (1005)
"It was great!! A nice hotel in a great location. "
United States
James J
The price is €96
includes taxes & fees
11 Jan - 12 Jan 2026
Days Inn by Wyndham Abilene
Room amenity
Candlewood Suites ABILENE by IHG

Candlewood Suites ABILENE by IHG

Candlewood Suites ABILENE by IHG
2.5 star property
5.3 km from Abilene Regional Medical Center
7.8 out of 10, Good, (407)
"My room was canceled at the staff were incredibly Rude. They said because I was a second party booking I got cancelled because they Overbooked. My not use Expedia ever again."
United States
John
The price is €124
includes taxes & fees
4 Jan - 5 Jan 2026
Candlewood Suites ABILENE by IHG
Seasonal outdoor pool
Comfort Suites Abilene Central

Comfort Suites Abilene Central

Comfort Suites Abilene Central
2.5 star property
4.9 km from Abilene Regional Medical Center
7.6 out of 10, Good, (1000)
"All staff are very nice and Hospitality especially the lady service in dining room, and also close to the AF base or shopping. I recommend this place to anyone if you need to close to your airmen when you want to go to visit them like I did "
United States
Thao
The price is €107
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Abilene Central
Terrace/patio
Home2 Suites by Hilton Abilene

Home2 Suites by Hilton Abilene

Home2 Suites by Hilton Abilene
3.0 star property
12.2 km from Abilene Regional Medical Center
9.4 out of 10, Exceptional, (603)
"Everything was great and staff was very helpful and friendly "
United States
Anonymous traveller
The price is €191
includes taxes & fees
31 Dec - 1 Jan 2026
Home2 Suites by Hilton Abilene
Outdoor pool, open 10:00 AM to 10:00 PM, pool loungers
TownePlace Suites by Marriott Abilene Northeast

TownePlace Suites by Marriott Abilene Northeast

TownePlace Suites by Marriott Abilene Northeast
3.0 star property
12.2 km from Abilene Regional Medical Center
9.4 out of 10, Exceptional, (742)
"Great place to stay. Kerri was wonderful! "
United States
Anonymous traveller
The price is €211
includes taxes & fees
31 Dec - 1 Jan 2026
TownePlace Suites by Marriott Abilene Northeast
Exterior
La Quinta Inn & Suites by Wyndham Abilene Mall

La Quinta Inn & Suites by Wyndham Abilene Mall

La Quinta Inn & Suites by Wyndham Abilene Mall
3.0 star property
5.4 km from Abilene Regional Medical Center
7.4 out of 10, Good, (1001)
"Good stay"
United States
William
The price is €113
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham Abilene Mall
Premium bedding, desk, laptop workspace, blackout curtains
Courtyard by Marriott Abilene Northeast

Courtyard by Marriott Abilene Northeast

Courtyard by Marriott Abilene Northeast
3.0 star property
12.3 km from Abilene Regional Medical Center
9.4 out of 10, Exceptional, (802)
"I was pleasantly surprised at the food choices and quality at the Bistro in the lobby of the hotel!"
United States
Sherri
The price is €198
includes taxes & fees
3 Jan - 4 Jan 2026
Courtyard by Marriott Abilene Northeast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Abilene Regional Medical Center Hotel Reviews

Abilene Whitten Inn

Abilene Whitten Inn

10/10 Excellent
"Everything was excellent. The staff is very friendly."
John 1-night trip
Posted 6 hours ago
Abilene Whitten Inn

Hotels near other Abilene Regional Medical Center attractions

Kirby Lake

4.2/5 (11 reviews)
Commune with nature and explore the great outdoors at Kirby Lake during your travels in Abilene. Visit the shops and top-notch restaurants in this family-friendly area.
See properties

The Winery at Willow Creek

You can enjoy a tasting or tour at The Winery at Willow Creek during your travels to Abilene. Visit the shops and top-notch restaurants in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Abilene Regional Medical Center?
Abilene Regional Medical Center is located in Abilene. This family-friendly area is known for its array of dining options and major shopping area. You'll find 129 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Abilene Regional Medical Center?
Adjacent to Abilene Regional Medical Center, Comfort Inn & Suites Regional Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. Other good choices within a few miles include MCM Elegante Suites Abilene and Days Inn by Wyndham Abilene.
How many hotels will I be able to find near Abilene Regional Medical Center?
Expedia has 129 hotels and other accommodation options a few miles from Abilene Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Abilene Regional Medical Center, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the top deals on offer near Abilene Regional Medical Center.