Appleton Hotel Guide - Appleton Medical Center hotels in Appleton, United States of America.

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
19 Dec - 20 Dec
Tomorrow
20 Dec - 21 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Appleton Medical Center hotels

Suite, 1 King Bed, Non Smoking, Jetted Tub (Walk-in Shower;with Sofabed)
CopperLeaf Boutique Hotel & Spa, BW Premier Collection

CopperLeaf Boutique Hotel & Spa, BW Premier Collection

CopperLeaf Boutique Hotel & Spa, BW Premier Collection
3.5 star property
2.2 km from Appleton Medical Center
9.4 out of 10, Exceptional, (1000)
"Such a cute place!"
United States
Mary
The price is €118
includes taxes & fees
29 Dec - 30 Dec
CopperLeaf Boutique Hotel & Spa, BW Premier Collection
Desk, iron/ironing board, free WiFi, bed sheets
Courtyard by Marriott Appleton Riverfront

Courtyard by Marriott Appleton Riverfront

Courtyard by Marriott Appleton Riverfront
3.0 star property
2.1 km from Appleton Medical Center
9.4 out of 10, Exceptional, (432)
"We love this spot! The suites are sizable, the mattresses are outstanding and the scenery around it is beautiful. "
United States
Kathryn
The price is €141
includes taxes & fees
25 Dec - 26 Dec
Courtyard by Marriott Appleton Riverfront
Premium bedding, in-room safe, desk, rollaway beds
Hilton Appleton Paper Valley

Hilton Appleton Paper Valley

Hilton Appleton Paper Valley
3.5 star property
2.2 km from Appleton Medical Center
8.6 out of 10, Excellent, (1003)
"Hotel is clean amenities were nice and it was very quiet. Excellent area around the hotel and easy to find dining and drinking options."
United States
Kristin
The price is €88
includes taxes & fees
29 Dec - 30 Dec
Hilton Appleton Paper Valley
Indoor pool
Cambria Hotel Appleton

Cambria Hotel Appleton

Cambria Hotel Appleton
3.0 star property
3.2 km from Appleton Medical Center
8.8 out of 10, Excellent, (985)
"Comfy bed!"
United States
Nancy
The price is €90
includes taxes & fees
29 Dec - 30 Dec
Cambria Hotel Appleton
Lobby
AmericInn by Wyndham Appleton North/Little Chute

AmericInn by Wyndham Appleton North/Little Chute

AmericInn by Wyndham Appleton North/Little Chute
2.0 star property
3.1 km from Appleton Medical Center
7.6 out of 10, Good, (1000)
"It was a great stay...."
United States
Kelly
The price is €68
includes taxes & fees
15 Jan - 16 Jan 2026
AmericInn by Wyndham Appleton North/Little Chute
Lobby
Fairfield Inn & Suites by Marriott Appleton

Fairfield Inn & Suites by Marriott Appleton

Fairfield Inn & Suites by Marriott Appleton
3.5 star property
6.1 km from Appleton Medical Center
9.6 out of 10, Exceptional, (230)
"Front desk/check in was great! Kind and informative. Thank you!"
United States
Ashley
The price is €107
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott Appleton
Restaurant
Hampton Inn Appleton-Fox River Mall Area

Hampton Inn Appleton-Fox River Mall Area

Hampton Inn Appleton-Fox River Mall Area
2.5 star property
6 km from Appleton Medical Center
9.4 out of 10, Exceptional, (1002)
"Great place to stay"
Canada
Daniel Patrick
The price is €96
includes taxes & fees
29 Dec - 30 Dec
Hampton Inn Appleton-Fox River Mall Area
Lobby
Cobblestone Hotel & Suites-Little Chute

Cobblestone Hotel & Suites-Little Chute

Cobblestone Hotel & Suites-Little Chute
3.0 star property
6.2 km from Appleton Medical Center
9.4 out of 10, Exceptional, (662)
"Good place to stay. "
United States
Kevin
The price is €79
includes taxes & fees
21 Dec - 22 Dec
Cobblestone Hotel & Suites-Little Chute
Exterior
Home2 Suites by Hilton Appleton

Home2 Suites by Hilton Appleton

Home2 Suites by Hilton Appleton
3.0 star property
7.3 km from Appleton Medical Center
9.6 out of 10, Exceptional, (655)
"Clean and comfortable"
United States
Derek
The price is €100
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites by Hilton Appleton
Exterior
Holiday Inn Appleton by IHG

Holiday Inn Appleton by IHG

Holiday Inn Appleton by IHG
3.0 star property
6.5 km from Appleton Medical Center
9.2 out of 10, Wonderful, (490)
"Was nice and warm"
United States
Jesus
The price is €94
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Appleton by IHG
Lobby
DoubleTree by Hilton Appleton

DoubleTree by Hilton Appleton

DoubleTree by Hilton Appleton
4.0 star property
6.2 km from Appleton Medical Center
9.0 out of 10, Wonderful, (1384)
"Nice shower"
United States
Andrew
The price is €88
includes taxes & fees
1 Jan - 2 Jan 2026
DoubleTree by Hilton Appleton
Indoor pool, pool loungers
Comfort Suites Appleton Airport

Comfort Suites Appleton Airport

Comfort Suites Appleton Airport
2.5 star property
5.5 km from Appleton Medical Center
8.8 out of 10, Excellent, (919)
"Clean room and great staff!"
United States
Jeanine
The price is €100
includes taxes & fees
20 Jan - 21 Jan 2026
Comfort Suites Appleton Airport
Exterior
Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area

Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area

Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area
2.5 star property
6 km from Appleton Medical Center
8.8 out of 10, Excellent, (1002)
"All around nice place to stay."
United States
Peggy
The price is €81
includes taxes & fees
29 Dec - 30 Dec
Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area
Indoor pool, pool loungers
AmericInn by Wyndham Appleton Downtown

AmericInn by Wyndham Appleton Downtown

AmericInn by Wyndham Appleton Downtown
2.5 star property
5 km from Appleton Medical Center
8.4 out of 10, Very good, (1003)
"Staff is very nice and accommodating we stay there every year."
United States
Linda
The price is €75
includes taxes & fees
6 Jan - 7 Jan 2026
AmericInn by Wyndham Appleton Downtown
Fridge, microwave, stovetop, coffee/tea maker
Candlewood Suites Appleton by IHG

Candlewood Suites Appleton by IHG

Candlewood Suites Appleton by IHG
2.5 star property
6.5 km from Appleton Medical Center
8.8 out of 10, Excellent, (477)
"Staff very friendly, great location. Loved my stay!"
United States
Calvert
The price is €70
includes taxes & fees
24 Dec - 25 Dec
Candlewood Suites Appleton by IHG
Fridge, microwave, stovetop, dishwasher
MainStay Suites Appleton Airport - Fox River Mall Area

MainStay Suites Appleton Airport - Fox River Mall Area

MainStay Suites Appleton Airport - Fox River Mall Area
3.0 star property
6.2 km from Appleton Medical Center
8.6 out of 10, Excellent, (201)
"Friendly employees, great amenities, room had everything needed"
United States
Axel
The price is €70
includes taxes & fees
21 Dec - 22 Dec
MainStay Suites Appleton Airport - Fox River Mall Area
Traditional Room, 2 Queen Beds
Four Points by Sheraton Appleton

Four Points by Sheraton Appleton

Four Points by Sheraton Appleton
3.0 star property
6.3 km from Appleton Medical Center
8.6 out of 10, Excellent, (1000)
"Room was very clean, staff was really helpful. Great stay!"
United States
Calvert
The price is €91
includes taxes & fees
24 Dec - 25 Dec
Four Points by Sheraton Appleton
Interior
Wingate by Wyndham Appleton

Wingate by Wyndham Appleton

Wingate by Wyndham Appleton
2.5 star property
6.1 km from Appleton Medical Center
8.4 out of 10, Very good, (1001)
"Great room at a great price!"
United States
Jeffrey
The price is €78
includes taxes & fees
30 Dec - 31 Dec
Wingate by Wyndham Appleton
Indoor pool
Wyndham Garden Appleton

Wyndham Garden Appleton

Wyndham Garden Appleton
2.5 star property
6.2 km from Appleton Medical Center
8.4 out of 10, Very good, (1005)
"My room was clean, the place is quiet, the food was great and the staff were very nice. "
United States
Shameaka
The price is €105
includes taxes & fees
21 Dec - 22 Dec
Wyndham Garden Appleton
Front of property
GrandStay Hotel & Suites Kaukauna

GrandStay Hotel & Suites Kaukauna

GrandStay Hotel & Suites Kaukauna
2.0 star property
9.7 km from Appleton Medical Center
9.4 out of 10, Exceptional, (46)
"Very clean and convenient for Green Bay. staff were friendly and courteous. A nice hotel"
United States
John
The price is €88
includes taxes & fees
11 Jan - 12 Jan 2026
GrandStay Hotel & Suites Kaukauna
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Appleton Medical Center Hotel Reviews

Wyndham Garden Appleton

Wyndham Garden Appleton

10/10 Excellent
"It was all excellant"
Laura 2-night trip
Posted 3 days ago
Wyndham Garden Appleton

Hotels near other Appleton Medical Center attractions

Erb Park

4.1/5 (43 reviews)
After visiting Erb Park, make a plan to see the other sights and activities in Appleton. Attend a sporting event or visit the shops in this family-friendly area.
See properties

Super Bowl Family Entertainment Center

You can take time to visit Super Bowl Family Entertainment Center during your travels to Appleton. Visit the shops and top-notch restaurants in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Appleton Medical Center?
Appleton Medical Center is located in a family-friendly area of Appleton that travellers like for its breweries and sporting events. If you're looking for a convenient place to stay, take a look at the 31 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Appleton Medical Center?
Hilton Appleton Paper Valley is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. It's located 1.4 mi (2.2 km) from Appleton Medical Center. Other good options within 5 miles include AmericInn by Wyndham Appleton Downtown and CopperLeaf Boutique Hotel & Spa, BW Premier Collection.
How many hotels will I find close to Appleton Medical Center?
Expedia has 31 hotels and other accommodation options within a mile from Appleton Medical Center.
If I need to cancel the hotel reservation for my stay near Appleton Medical Center, will I receive a refund?
Yes, most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available near Appleton Medical Center.
What can I see and do near Appleton Medical Center?
You'll want to browse the collections at Paper Discovery Center, Hearthstone Historic House Museum and History Museum at the Castle. You can wander around Appleton Memorial Park, Gordon Bubolz Nature Preserve or Erb Park if you want a dose of fresh air. Gardens of the Fox Cities, Building for Kids Children's Museum and Badger Sports Park are fun stops for the whole family while you're in town.