Panama City Hotel Guide - Avenida Central hotels in Panama City, Panama.

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Avenida Central hotels

La Isabela Suites

La Isabela Suites
3.5 star property
San Felipe, 1 km from Avenida Central
10.0 out of 10, Exceptional, (171)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
La Isabela Suites

Hotel Plaza Herrera

Hotel Plaza Herrera
4.0 star property
San Felipe, 1.1 km from Avenida Central
10.0 out of 10, Exceptional, (14)
"Hotel Plaza Herrera is a real gem and the staff is all diamonds! We will be back! "
United States
Neal
The price is €268
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Plaza Herrera

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
San Felipe, 1 km from Avenida Central
9.8 out of 10, Exceptional, (259)
"Great location!"
United States
Erik
The price is €351
includes taxes & fees
10 Jan - 11 Jan 2026
Hotel La Compañía Casco Antiguo

Las Clementinas

Las Clementinas
3.5 star property
San Felipe, 0.9 km from Avenida Central
9.4 out of 10, Exceptional, (172)
"Fabulous room and wonderful people that work there. "
Canada
Leah
The price is €130
includes taxes & fees
11 Jan - 12 Jan 2026
Las Clementinas

Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 1 km from Avenida Central
9.4 out of 10, Exceptional, (259)
"Great hotel, heart of old town and near great restaurants and sights. Extremely friendly and helpful staff. Highly recommended "
United States
Ashish
The price is €132
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel San Felipe

La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
San Felipe, 0.9 km from Avenida Central
9.6 out of 10, Exceptional, (195)
"Beautiful room Good location"
United States
Karla
The price is €282
includes taxes & fees
13 Jan - 14 Jan 2026
La Concordia Boutique Hotel

American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 1 km from Avenida Central
9.4 out of 10, Exceptional, (615)
"The staffs are very nice, friendly and helpful"
United States
Dianne Marie
American Trade Hotel

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.4 km from Avenida Central
9.8 out of 10, Exceptional, (568)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is €334
includes taxes & fees
13 Jan - 14 Jan 2026
Sofitel Legend Casco Viejo, Panama City

Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo
3.0 star property
San Felipe, 1.2 km from Avenida Central
9.6 out of 10, Exceptional, (108)
"Excellent location; friendly/helpful staff: clean/well-appointed rooms with lots of local character. "
United States
Brooke
Amarla Boutique Hotel Casco Viejo

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana, 0.8 km from Avenida Central
9.2 out of 10, Wonderful, (57)
"We live this property and stay here whenever we are in town."
United States
chris
Casco View Apartments

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 1.2 km from Avenida Central
9.2 out of 10, Wonderful, (1000)
"Nice hotel in the historic center, excellent location for sightseeing and walking around at night."
United States
Antonio
The price is €333
includes taxes & fees
2 Jan - 3 Jan 2026
Central Hotel Panama Casco Viejo

Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 1 km from Avenida Central
8.8 out of 10, Excellent, (276)
"Staff was amazing!! Room was great as well!! "
United States
John
Tantalo Hotel

La Cuadra by Wynwood House

La Cuadra by Wynwood House
3.5 star property
El Chorrillo, 1 km from Avenida Central
9.2 out of 10, Wonderful, (45)
"Love the property. You are right at the start of the nice part of casco viejo but the blocks around it are rough and ugly. The police are very prominent so it's safe but be on alert"
United States
Carlos
The price is €126
includes taxes & fees
4 Jan - 5 Jan 2026
La Cuadra by Wynwood House

Magnolia Inn

Magnolia Inn
2.0 star property
San Felipe, 1 km from Avenida Central
8.8 out of 10, Excellent, (421)
"Excelent location , friendly staff and cute hotel"
Canada
Renata
The price is €74
includes taxes & fees
4 Jan - 5 Jan 2026
Magnolia Inn

Oasis Hotel

Oasis Hotel
3.0 star property
San Felipe, 0.9 km from Avenida Central
8.6 out of 10, Excellent, (109)
"Our stay was exceptional! The room was clean, bed comfortable, amazing balcony view, very sweet staff, fun rooftop bar with delicious food. Definitely recommend staying at The Oasis."
United States
Michele
The price is €69
includes taxes & fees
18 Jan - 19 Jan 2026
Oasis Hotel

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 2.8 km from Avenida Central
10.0 out of 10, Exceptional, (146)
"Great hotel fair price"
United States
Santiago
The price is €149
includes taxes & fees
10 Jan - 11 Jan 2026
Hyatt Regency Panama City

The Balboa Inn

The Balboa Inn
3.0 star property
Balboa, 1.6 km from Avenida Central
9.0 out of 10, Wonderful, (126)
"Wonderful staff. Thank you."
United States
JOHN
The price is €55
includes taxes & fees
1 Jan - 2 Jan 2026
The Balboa Inn

Yoo by Wynwood House

Yoo by Wynwood House
4.0 star property
Calidonia, 1.5 km from Avenida Central
9.2 out of 10, Wonderful, (5)
"I will be back!"
United States
Jeffrey
The price is €194
includes taxes & fees
29 Jan - 30 Jan 2026
Yoo by Wynwood House

Canova

Canova
3.0 star property
Calidonia, 0.9 km from Avenida Central
8.2 out of 10, Very good, (132)
"Very close place to everything. Very affordable. "
United States
Alex
The price is €27
includes taxes & fees
18 Jan - 19 Jan 2026
Canova

Corcho

Corcho
3.0 star property
San Felipe, 1 km from Avenida Central
8.6 out of 10, Excellent, (26)
"Was very clean and walking distance to the most turistic places in the old town"
Canada
Hazel
The price is €115
includes taxes & fees
5 Jan - 6 Jan 2026
Corcho
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Avenida Central Hotel Reviews

Hotels near other Avenida Central attractions

Frequently asked questions

What's the area like around Avenida Central?
Avenida Central is located in Panama City. Travellers like this budget-friendly area for its shopping. If you're looking for a convenient place to stay, take a look at the 603 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Avenida Central?
Adjacent to Avenida Central, Hotel República is one of the top choices for your stay based on our traveller data, and this hotel offers a rooftop terrace and free WiFi. Other good options close by include Central Hotel Panama Casco Viejo and Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals.
How many hotels will I find close to Avenida Central?
Expedia has 603 hotels and other accommodation options within a mile from Avenida Central.
If I need to cancel the hotel reservation for my stay near Avenida Central, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Avenida Central.
What can I see and do near Avenida Central?
Interoceanic Canal Museum, Biomuseo and Museum of Contemporary Art Panama feature a variety of fascinating exhibits to see while you're in town. Explore notable local landmarks like Iglesia del Carmen, Panama Canal Railway and Miraflores Locks. You can watch performances at National Theater, Amador Theater and Anita Villalaz Theater if you're interested in local theatre.
How can I get to Avenida Central?
Local metro stations include Estación Lotería and Santo Tomas Station. If you'd like to venture around the surrounding area, you may want to rent a car for your trip.