Barrio Sur Holidays

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Where to stay in Barrio Sur

Find the best Barrio Sur areas and neighborhoods for the activities you enjoy most. Learn more about Barrio Sur
A statue of a historical figure pointing upwards with a bird in hand, set against a backdrop of a clear blue sky with scattered clouds.

Barrio Norte

1 out of top 10 points of interest in this area

If you're spending some time in Barrio Norte, Monument to Christopher Columbus and Limon Bay are top sights worth seeing.

Find hotels in Barrio Norte

Top hotels in Barrio Sur

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

4 out of 5
Paseo Gorgas, Calle 13 Colon Colon
Fully refundableReserve now, pay when you stay
The price is €108 per night from 29 Nov to 30 Nov
€108
29 Nov - 30 Nov
includes taxes & fees
8.2/10 Very good! (993 reviews)
"It’s very helpful staff and wonderful service"

Reviewed on 27 Oct 2026

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
Hotel Andros

Hotel Andros

3 out of 5
Ave. Herrera, entre Calles 9 y 10 Colon Colon
The price is €39 per night from 31 Oct to 1 Nov
€39
31 Oct - 1 Nov
includes taxes & fees
8/10 Very good! (188 reviews)
"On the inside it appears like a nice classy hotel. However, it is in the worst neighborhood I think I've ever been in. I was greeted at the door by an armed guard holding a shotgun. Parking lot was across the street, however had no issues parking my car there. The room was so small that you had to ..."

Reviewed on 29 Oct 2026

Hotel Andros
Hotel Sotelo

Hotel Sotelo

3 out of 5
Calle 11, Ave. Amador Colon Panama
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Hotel Sotelo
See all 56 properties in Barrio Sur
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Barrio Sur attractions

Colon Free Zone

7.8/10 (127 reviews)
During your trip to Colon, you can do some window-shopping at Colon Free Zone.
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Things to do

Panama Canal Tour: New Locks Agua Clara, Gatun & Atlantic Bridge

Panama Canal Tour: New Locks Agua Clara, Gatun & Atlantic Bridge

€44
per adult
Panama Canal Tour: New Locks Agua Clara, Gatun & Atlantic Bridge
Exploring the Two Oceans Old and New Canal Locks Private Tour

Exploring the Two Oceans Old and New Canal Locks Private Tour

€82
per adult
Exploring the Two Oceans Old and New Canal Locks Private Tour
Panama Canal and Fort San Lorenzo Tour from Colón

Panama Canal and Fort San Lorenzo Tour from Colón

€92
per adult
Panama Canal and Fort San Lorenzo Tour from Colón
See all activities in Colon
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.