
Cayos Los Grullos Holidays
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Top Flight + Hotel Deals in Cayos Los Grullos
Price found within the past 48 hours. Click for updated prices.


Hotel Plaza Herrera
Casco Viejo
per person
8 Sept - 13 Sept
found 5 hours ago
Return flight included
Shannon (SNN) to Panama City (PTY)
10/10 Exceptional! (3 reviews)
Staying at Hotel Herrera in Casco Viejo was truly unforgettable-one of those rare experiences where everything just feels right from the moment you arrive. Nestled right in the heart of Plaza Herrera, the hotel’s beautifully restored colonial façade immediately drew me in, but it was the warm welcome from the staff that really set the tone for my stay.
My suite was a perfect blend of historic charm and modern comfort, with gorgeous handcrafted furniture, and a balcony that overlooked the lively Plaza Herrera below. Every detail, from the plush bedding to the luxurious marble bathroom, made it feel like a boutique retreat. I loved waking up to the sounds of the city and sipping coffee while watching the world go by from my private balcony.
The hotel’s location made it easy to explore the best of Casco Viejo on foot-charming cafes, art galleries, and vibrant nightlife were all just steps away. The staff went above and beyond, offering great recommendations and even arranging a guided tour to the Panama Canal and a day trip to the Emberá community, which was a highlight of my trip.
Dining at Hotel Herrera was another standout. I treated myself to a special dinner in THEcellar, their exclusive private dining room, and it was an experience I’ll never forget. The food was incredible, and the intimate setting made it feel truly special.
If you’re looking for a place that combines history, luxury, and genuine hospitality, I can’t recommend Hotel Herrera enough.
Reviewed on 5 May 2025

La Concordia Boutique Hotel
Casco Viejo
per person
8 Sept - 13 Sept
found 5 hours ago
Return flight included
Shannon (SNN) to Panama City (PTY)
9.4/10 Exceptional! (176 reviews)
Wonderful location in historic city center - Casco Viejo. Superbly helpful staff - helped me make a few arrangements on short notice (airport transport, city guide, birdwatching guide). I certainly hope to return to Panamá.
Reviewed on 21 Jul 2025


Casa Mallet by Wynwood House
Casco Viejo
per person
8 Sept - 13 Sept
found 5 hours ago
Return flight included
Shannon (SNN) to Panama City (PTY)
9.8/10 Exceptional! (21 reviews)
It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment.
Reviewed on 23 Jul 2025
Top hotels in Cayos Los Grullos

San Blas Private Over-the-Water Cabin
Nusatupo, Narganá, Guna Yala
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling ..."
Reviewed on 27 Oct 2022


Cabanas Narasgandub - Naranjo Chico
Kuna Yala, Narganá, Guna Yala
Beautiful scenery and an amazing community
"Our stay at Cabanas Narasgandub was everything you would expect from a remote and rustic location. You will rise when the rooster crows at the crack of dawn and likely be sleepy shortly after the sun goes down. The cabins are extremely rustic and this location is not for someone expecting a 5 star ..."
Reviewed on 27 Sep 2019
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Cayos Los Grullos

San Blas Islands Tour - Visit Paradise Islands + Lunch + Drink
€68
per adult

All inclusive San Blas Islands Day Tour from Panama City
€146
per adult

San Blas Money Heist Island Day tour - Visit 3-islands + Natural Pool
€65
per adult
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.