
Depew Holidays
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Better together
Save up to €185 when you book a flight and hotel together*
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With over 300,000 hotels worldwide, it's easy to create a perfect package
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Top hotels in Depew

M Hotel Buffalo
2040 Walden Ave, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is €96 per night from 26 Aug to 27 Aug
€96
26 Aug - 27 Aug
includes taxes & fees
7.2/10 Good! (1,983 reviews)
"Enjoying and relaxing"
Reviewed on 21 Aug 2025

Buffalo Airport Hotel
4600 Genesee St, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is €104 per night from 26 Aug to 27 Aug
€104
26 Aug - 27 Aug
includes taxes & fees
7.8/10 Good! (2,605 reviews)
"Easy checkin. Adequate parking. Quiet."
Reviewed on 21 Aug 2025

Hyatt Regency Buffalo / Hotel and Conference Center
Two Fountain Plaza, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is €124 per night from 1 Sept to 2 Sept
€124
1 Sept - 2 Sept
includes taxes & fees
7.8/10 Good! (1,498 reviews)
"nice place to stay"
Reviewed on 21 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Buffalo Zoo
See more than 1,200 animals at this small zoo in Buffalo’s Delaware Park. Explore the rainforest building or see the big cats of the African plains.

Canisius College
Explore the campus of Canisius College during your trip to Buffalo. Experience the area's great live music and entertainment choices.

Buffalo Museum of Science
Enter a world where you can explore weather, bodies, bugs, physics and more, all in one place. Buffalo’s world-class science museum also features a 3-D movie theater.
What to do in Depew

Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour
€11
per adult
100% of travellers recommend

Niagara Falls Self-Guided Driving Audio Tour from Toronto
€15
per traveller

Self-Guided Buffalo Scavenger Hunt: Roaming Buffalo
€11
per adult
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.