A park with a fountain, lush greenery, and a stone wall.

Best Western hotels in East Central Iowa, Iowa

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Check prices for these dates

Tonight
29 Sept - 30 Sept
Tomorrow
30 Sept - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for East Central Iowa Best Western

1. Best Western Airport Inn

Best Western Airport Inn
Moline
United States
Megan
€67
includes taxes & fees
1 Oct - 2 Oct
Best Western Airport Inn

2. Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel
Muscatine
United States
Harvey
€93
includes taxes & fees
4 Oct - 5 Oct
Best Western Muscatine / Pearl City Hotel
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Top East Central Iowa Hotel Reviews

Hotel Millwright

Hotel Millwright

10/10 Excellent
"A great place for a comfortable stay."
Matthew 2-night trip
Posted 3 hours ago
Hotel Millwright
Drury Inn & Suites Iowa City Coralville

Drury Inn & Suites Iowa City Coralville

10/10 Excellent
"Hands down, was a great place to stay! Near many good places to eat or drink."
Jesurun 1-night trip
Posted 4 hours ago
Drury Inn & Suites Iowa City Coralville
Heartland Inn

Heartland Inn

10/10 Excellent
"Helpful and friendly staff. Just wish there was an exercise room."
Patricia 1-night trip
Posted 22 hours ago
Heartland Inn
Comfort Suites Coralville I-80

Comfort Suites Coralville I-80

10/10 Excellent
"Great hotel with amazing hot tub"
William 1-night trip
Posted 23 hours ago
Comfort Suites Coralville I-80
Quality Inn Coralville - Iowa River Landing

Quality Inn Coralville - Iowa River Landing

8/10 Good
"Since it was just me traveling, it was okay. I made due with what I had. I didn’t have the breakfast since my appointments that I was in town for said not to eat. The room was clean, the bed was comfortable for me (I have a bad back, firm bed was good for me, pillows were pretty good too for my neck), the refrigerator was left open before I got there (looked like it had been defrosted). The bathroom was really small, to use the toilet I had to step completely in the bathroom almost to other wall to shut the door. I went to run bath water and the top of the tub plug was missing so I couldn’t tell if it was water flow or stopped. Staff was helpful, the front desk person came and looked at the tub when I couldn’t get the water to drain (even after removing the mechanism from the drain). I thought the shower water pressure was awesome! The TV only had about 20 channels, the guide book on the desk was outdated and those channels listed there weren’t valid. Besides those few things, not a bad experience just some things need updating. For 1 person for a night or two, the price was right and it worked for me."
Miranda 1-night trip
Posted 1 day ago
Quality Inn Coralville - Iowa River Landing
La Quinta Inn & Suites by Wyndham Coralville Iowa City

La Quinta Inn & Suites by Wyndham Coralville Iowa City

10/10 Excellent
"The room was nice but I was surprised that La Quinta now requires a $75 a night deposit. That's something everyone needs to know when they stop there"
Susan 1-night trip
Posted 1 day ago
La Quinta Inn & Suites by Wyndham Coralville Iowa City
Isle Casino Hotel Bettendorf - A Caesars Rewards Destination

Isle Casino Hotel Bettendorf - A Caesars Rewards Destination

10/10 Excellent
"Great hotel with casino! Super clean. Wish there was a hot tub-just one negative."
Kelly 1-night trip
Posted 2 days ago
Isle Casino Hotel Bettendorf - A Caesars Rewards Destination
American Inn Cedar Rapids South

American Inn Cedar Rapids South

8/10 Good
"This was my first time staying at this hotel, as I was in town on business. It appears the hotel had recently undergone some remodeling when I stayed in September 2026, and the updates made the property feel clean, fresh, and well cared for. Overall, I had a very good stay and wouldn’t hesitate to stay here again. The breakfast wasn’t anything exceptional, but it covered the essentials...hot waffles, coffee, juice, and a few other options. For a 2-star hotel, it was actually better than what I’ve experienced at many comparable properties. Overall, a comfortable stay and a good value."
Vincent 1-night trip
Posted 2 days ago
American Inn Cedar Rapids South
Comfort Inn & Suites Davenport - Quad Cities

Comfort Inn & Suites Davenport - Quad Cities

10/10 Excellent
"Great overnight stay! Room was clean, staff was very friendly and attentive and the buffet breakfast was good. The gravy for biscuits was delicious. Highly recommend!"
Tiffany 1-night trip
Posted 3 days ago
Comfort Inn & Suites Davenport - Quad Cities

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