East Prairie
Travel Guide
Visit East Prairie

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
The price is €62 per night from 2 Nov to 3 Nov
€62
2 Nov - 3 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,004 reviews)
"Kayla at the front desk was very helpful and accommodating when I first arrived. The room was very generous in space, clean and comfortable. A very quiet place to spend a night after 12 hours on the saddle."
Reviewed on 8 Oct 2025

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
The price is €89 per night from 19 Oct to 20 Oct
€89
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
"The room was just ok. The carpet wasn't vacuumed and my room didn't have any trash bags. There were a lot of crumbs on the floor and the channel guide was dirty. Like a brown sticky sauce or something was on it. The mattress was not the most comfortable and the pillows were lumpy. not fluffy at ..."
Reviewed on 11 Oct 2025

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
The price is €76 per night from 18 Oct to 19 Oct
€76
18 Oct - 19 Oct
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,011 reviews)
"Good location. Clean rooms. Comfortable bed. Good breakfast."
Reviewed on 11 Oct 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
9.8/10 Exceptional! (210 reviews)
"Dwelling was super clean and smelled wonderful when you walked in. Very well kept. The owner was very much in contact letting you know he was there if needed. The location and views are amazing. Definitely recommended and look forward to visiting in the future."
Reviewed on 10 Oct 2025

Log Cabin.
Hornbeak
Stay at this cabin in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Lake Isom National Wildlife Refuge and Willow Towhead are ...
9.2/10 Wonderful! (31 reviews)
"The cabin is beautiful! Had no issues at all. Slept all 14 of us easily and could have slept more. The pond was the kids favorite, loved fishing out of it."
Reviewed on 2 Sept 2025

Dancing Diamonds Waterfront Retreat
Tiptonville
Stay at this vacation home in Tiptonville. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Reelfoot Lake State Park and Campbell's Point ...
10/10 Exceptional! (95 reviews)
"Family friendly house at Reelfoot with water access. Great host and clean house. We explored the state park then drove up to Discovery Park in Union City. Good restaurants around. Great getaway lake house."
Reviewed on 29 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Big Oak Tree State Park
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.