A tree-lined landscape with a river and fields.

East Prairie Hotels

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Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

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Our top choices for East Prairie hotels

Breakfast included
Exterior

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (420 reviews)
"Staff was excellent. It was fine for what it was — a cheap place near the highway"
United States
Emily
The price is €69
includes taxes & fees
17 Jul - 18 Jul
The Riverstone Hotel Charleston-Sikeston
Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,017 reviews)
"Great place!"
United States
Jennifer
The price is €112
includes taxes & fees
12 Aug - 13 Aug
Drury Inn & Suites Sikeston, MO
Room, 1 Queen Bed, Non Smoking

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (68 reviews)
"Clean room, The receptionist very friendly, good parking."
United States
Temera
The price is €70
includes taxes & fees
15 Jul - 16 Jul
Super 8 By Wyndham Marston
Premier Room, 1 Bedroom, Non Smoking

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (784 reviews)
"Great stay with Great people, very clean and welcoming"
United States
Mircea
The price is €54
includes taxes & fees
19 Jul - 20 Jul
New Orleans Inn Portageville
Desk, blackout curtains, iron/ironing board (on request), free WiFi

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (799 reviews)
"I love it there."
United States
Sharika West
The price is €73
includes taxes & fees
15 Jul - 16 Jul
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (479 reviews)
"Nice!"
United States
theresa
The price is €98
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Express & Suites Sikeston Southwest by IHG
Free buffet breakfast

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.2 out of 10, Very good, (532 reviews)
"Breakfast was filling and fresh. Short overnight stay which completely met our needs First level room with convenient vehicle parking right outside the door which made moving luggage painless. "
United States
Lisa
The price is €73
includes taxes & fees
9 Aug - 10 Aug
Quality Inn Union City US 51
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (99 reviews)
"Great stay, kind staff, very clean property."
United States
Joni
The price is €109
includes taxes & fees
9 Aug - 10 Aug
Fairfield Inn & Suites by Marriott Sikeston
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (590 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is €113
includes taxes & fees
22 Jul - 23 Jul
Hampton Inn Sikeston
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (648 reviews)
"Clean rooms,"
United States
Karl
The price is €58
includes taxes & fees
19 Jul - 20 Jul
Super 8 by Wyndham Charleston/Sikeston East MO
Iron/ironing board, free WiFi, bed sheets

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (142 reviews)
"Enjoyed our stay. All the appliances worked and our air conditioner kept us cool! Will definitely stay here again!"
United States
Sheryl
The price is €60
includes taxes & fees
15 Jul - 16 Jul
Country Yard Inn and Suite
Free daily full breakfast

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,006 reviews)
"Very friendly and helpful staff. Everything I saw was that Mgmt is on point and I would highly recommend staying !!"
United States
Gregory
The price is €87
includes taxes & fees
12 Aug - 13 Aug
Best Western Plus Sikeston I-55
Lobby

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (413 reviews)
"The room was clean, the breakfast was good. We enjoyed our stay."
United States
David
The price is €88
includes taxes & fees
11 Aug - 12 Aug
Sleep Inn at Discovery Park of America
Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (291 reviews)
"Breakfast was sparse. This motel needs a complete overhaul. "
United States
Susan
The price is €66
includes taxes & fees
25 Jul - 26 Jul
Quality Inn Cairo I-57
Standard Room, 2 Double Beds, Non Smoking

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (500 reviews)
"The lake view was beautiful and staff was amazing"
United States
Richard
The price is €62
includes taxes & fees
31 Jul - 1 Aug
Reelfoot Lake Inn
1 bedroom, desk, laptop workspace, blackout curtains

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,005 reviews)
"Business friendly, clean room staff very friendly, accommodating."
United States
Janice
The price is €68
includes taxes & fees
10 Aug - 11 Aug
Days Inn and Suites by Wyndham Sikeston
Property amenity

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is €126
includes taxes & fees
30 Jul - 31 Jul
TownePlace Suites by Marriott Sikeston
Free WiFi, bed sheets

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (125 reviews)
"Quiet safe area."
United States
Frank
The price is €57
includes taxes & fees
15 Jul - 16 Jul
Travel Inn Marston I-55 by Hotel O
Terrace/patio

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (189 reviews)
"Quick over night stay. Room was clean, complementary breakfast was good"
United States
Sarah
The price is €111
includes taxes & fees
12 Aug - 13 Aug
Hampton Inn Union City
Room, 1 King Bed, Accessible, Non Smoking

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (657 reviews)
"Staff is great rooms clean no bugs and bed was comfortable "
United States
James
The price is €64
includes taxes & fees
3 Aug - 4 Aug
Super 8 by Wyndham Sikeston/Miner Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
A tree-lined landscape with a river and fields.

Top East Prairie Hotel Reviews

Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

10/10 Excellent
"As described. Place is nice great for the family we had thereBack deck is beautiful, fishing wasn’t too successful, but we had a nice time there. Very responsive and no surprises"
Christi C. 3-night trip
Posted 22 hours ago
Duck Hunting, Fishing or Relaxing Family Vacation

More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is €68 per night from 10 Aug to 11 Aug
€68
10 Aug - 11 Aug
includes taxes & fees
7.2/10 Good! (1,005 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Best Western Plus Sikeston I-55 and Days Inn and Suites by Wyndham Sikeston. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best holiday rentals that East Prairie has to offer?
Duck Hunting, Fishing or Relaxing Family Vacation: This holiday home rental outside of East Prairie is located on a lake, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 36 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Mississippi River and Big Oak Tree State Park exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.

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