East Prairie Hotels

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Check prices for these dates

Next weekend
5 Jun - 7 Jun
In two weeks
12 Jun - 14 Jun

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Our top choices for East Prairie hotels

Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,001 reviews)
"Breakfast was good,pool hot tub excellent "
United States
Janica
The price is €109
includes taxes & fees
28 Jun - 29 Jun
Drury Inn & Suites Sikeston, MO
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (569 reviews)
"Very clean hotel with comfortable bedding. Front desk staff was very nice and accommodating as we were traveling with a small dog."
United States
Connie
The price is €103
includes taxes & fees
12 Jun - 13 Jun
Hampton Inn Sikeston
Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
"All very just okay "
United States
Sherry
The price is €71
includes taxes & fees
8 Jun - 9 Jun
The Riverstone Hotel Charleston-Sikeston
Lobby

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (393 reviews)
"Great stay. "
United States
Paul
The price is €81
includes taxes & fees
29 Jun - 30 Jun
Sleep Inn at Discovery Park of America
Individually decorated, individually furnished, desk, blackout curtains

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (783 reviews)
"We were very satisfied with our stay. We will make this a regular stay when traveling to or from Iowa."
United States
Carolyn
The price is €66
includes taxes & fees
8 Jun - 9 Jun
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Free buffet breakfast

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (515 reviews)
"Breakfast was filling and fresh. Short overnight stay which completely met our needs First level room with convenient vehicle parking right outside the door which made moving luggage painless. "
United States
Lisa
The price is €63
includes taxes & fees
24 Jun - 25 Jun
Quality Inn Union City US 51
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (636 reviews)
"It was not clean and didn't have a breakfast the coffee was terrible"
United States
vincent
The price is €58
includes taxes & fees
8 Jun - 9 Jun
Super 8 by Wyndham Charleston/Sikeston East MO
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (84 reviews)
"The breakfast was good, the service was good, and the staff was very friendly"
United States
Angela
The price is €107
includes taxes & fees
28 Jun - 29 Jun
Fairfield Inn & Suites by Marriott Sikeston
Free daily full breakfast

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,001 reviews)
"Breakfast was fresh and the room was clean. It's a good place to stay. Friendly staff. "
United States
Tabitha
The price is €97
includes taxes & fees
28 Jun - 29 Jun
Best Western Plus Sikeston I-55
Room, 1 Queen Bed, Non Smoking

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (64 reviews)
"Great hotel for the price!!! Remodel very nice and modern. "
United States
Amy
The price is €74
includes taxes & fees
31 May - 1 Jun
Super 8 By Wyndham Marston
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (466 reviews)
"Only stayed one night, no complaints"
United States
Zachary
The price is €102
includes taxes & fees
21 Jun - 22 Jun
Holiday Inn Express & Suites Sikeston Southwest by IHG
1 bedroom, desk, laptop workspace, blackout curtains

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,000 reviews)
"When I stay at hotels I like to find hotels like this one for the $$$ value . This hotel was clean and the bed was very comfortable. Room 237 . I didn’t hear any interstate noise . I didn’t eat the breakfast but the coffee was very good . I would stay here again ."
United States
Kurt
The price is €67
includes taxes & fees
2 Jun - 3 Jun
Days Inn and Suites by Wyndham Sikeston
Lobby

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (391 reviews)
"Yes"
United States
Lashae
The price is €58
includes taxes & fees
31 May - 1 Jun
Hospitality House Union City I 69 / US 51
Lobby

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (571 reviews)
"Very clean nice staff and well run "
United States
zach
The price is €61
includes taxes & fees
9 Jun - 10 Jun
Country Hearth Inn & Suites Union City
Exterior

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (293 reviews)
"nice room, clean. breakfast was great and lady keeping it full, hot, and clean!"
United States
Fred
The price is €100
includes taxes & fees
30 Jun - 1 Jul
Comfort Inn & Suites Sikeston I-55
Terrace/patio

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (183 reviews)
"The room was clean and comfortable. The staff was courteous during my entire stay."
United States
Alvin
The price is €113
includes taxes & fees
14 Jun - 15 Jun
Hampton Inn Union City
Room, 1 King Bed, Accessible, Non Smoking

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (632 reviews)
"Staff, A/C, adequate breakfast"
United States
David
The price is €62
includes taxes & fees
31 May - 1 Jun
Super 8 by Wyndham Sikeston/Miner Area
Property amenity

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"Room was very nice and in very clean condition and hotel staff was very helpful and polite. The breakfast was very delicious and coffee served all day. The hotel smelled very nice and had a very welcoming feeling. Will definitely book with them again"
United States
Joseph
The price is €123
includes taxes & fees
11 Jun - 12 Jun
TownePlace Suites by Marriott Sikeston
Standard Room, 2 Double Beds, Non Smoking

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (493 reviews)
"The lake view was beautiful and staff was amazing"
United States
Richard
The price is €69
includes taxes & fees
3 Jun - 4 Jun
Reelfoot Lake Inn
Premier Room, 1 Bedroom, Non Smoking

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (766 reviews)
"Parking was right outside my window so as safe as can be. The staff on the other hand are extremely helpful and wonderful to talk to. Very friendly and professional. "
United States
Honorio
The price is €53
includes taxes & fees
28 Jun - 29 Jun
New Orleans Inn Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

4.0/5 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
The Mississippi River near Hannibal, Missouri, USA

Top East Prairie Hotel Reviews

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent
"Great stay, kind staff, very clean property."
Joni 1-night trip
Posted 10 hours ago
Fairfield Inn & Suites by Marriott Sikeston

More cheap stays in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO
The price is €62 per night from 31 May to 1 Jun
€62
31 May - 1 Jun
includes taxes & fees
6.8/10 (632 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Hampton Inn Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best holiday rentals that East Prairie has to offer?
The Tackle Box at Reelfoot: This holiday home rental outside of East Prairie has air conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 33 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.

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