Cape Girardeau Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
29 May - 31 May
Next weekend
5 Jun - 7 Jun

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Cape Girardeau hotels

Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"clean room, easy parking, solid breakfast"
United States
Jeffrey
The price is €107
includes taxes & fees
7 Jun - 8 Jun
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
"We found this property to be everything someone would hope for in an overnight stay away from home."
United States
Richard
The price is €97
includes taxes & fees
28 Jun - 29 Jun
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (817 reviews)
"We enjoyed our stay"
United States
Wanda
The price is €102
includes taxes & fees
7 Jun - 8 Jun
Hampton Inn Cape Girardeau I 55 East
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean and comfortable room for a good price."
United States
Mary
The price is €90
includes taxes & fees
14 Jun - 15 Jun
Drury Inn & Suites Cape Girardeau
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (193 reviews)
"The hotel was super clean, very friendly, the beds were very comfortable."
United States
Candia
The price is €90
includes taxes & fees
14 Jun - 15 Jun
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (511 reviews)
"Great stay!!"
United States
Taylor
The price is €130
includes taxes & fees
18 Jun - 19 Jun
Courtyard by Marriott Cape Girardeau Downtown
Desk, laptop workspace, blackout curtains, free cots/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent layover stay"
United States
Wesley H.
The price is €70
includes taxes & fees
21 Jun - 22 Jun
Pear Tree Inn Cape Girardeau West
Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
"We love staying at this inn. It truly feels like we’re in a friend’s beautifully appointed home. We’ll be back here again for certain. "
United States
Elsa
The price is €146
includes taxes & fees
31 May - 1 Jun
Rockwood Inn
Snack bar

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (130 reviews)
"This is a clean, quiet, well designed hotel."
United States
Kendra
The price is €91
includes taxes & fees
14 Jun - 15 Jun
Tru By Hilton Cape Girardeau
Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (584 reviews)
"I ALWAYS stay here when I come to Cape! Wonderful, great place!"
United States
Audra
The price is €128
includes taxes & fees
1 Jun - 2 Jun
The Riverview
Room, 1 King Bed, Accessible, Non Smoking

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (746 reviews)
"Clean room - easy parking with a trailer"
United States
stephen
The price is €65
includes taxes & fees
7 Jun - 8 Jun
Quality Inn Cape Girardeau North
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (227 reviews)
"The bed was comfortable, the room clean it was a nice big room. Parking was good and there was a place to eat just across the parking lot. The Huddle In, good food nice staff and enjoyable."
United States
Rosealee
The price is €75
includes taxes & fees
30 May - 31 May
Town House Inn Cape Giradreau
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (948 reviews)
"It was a great place to stay. Convenient to go any where y"
United States
Marilyn
The price is €90
includes taxes & fees
1 Jun - 2 Jun
Candlewood Suites Cape Girardeau by IHG
Lobby

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,002 reviews)
"Clean room, friendly staff, good breakfast and dinner variety,large open parking, clean pool and exercise room. All around great stay. "
United States
Jeremy
The price is €78
includes taxes & fees
28 Jun - 29 Jun
Drury Inn & Suites Jackson MO
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (775 reviews)
"Nice hotel"
United States
Jeff
The price is €86
includes taxes & fees
1 Jun - 2 Jun
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very good, (767 reviews)
" Room was nice and staff courteous. We would stay there again for sure. "
United States
Stan
The price is €86
includes taxes & fees
21 Jun - 22 Jun
Comfort Suites Jackson-Cape Girardeau
Lobby sitting area

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (94 reviews)
"This was such a quaint hotel in Marble Hill. The staff was friendly and attentive and the breakfast and little store are such a fun addition. We will be back!"
United States
Betsy
The price is €96
includes taxes & fees
30 May - 31 May
EC Reed's Mercantile and Hotel
Indoor pool, outdoor pool

Hotel 7 Inn Anna

Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (227 reviews)
"Clean room staff was really nice"
United States
Levette
The price is €70
includes taxes & fees
31 May - 1 Jun
Hotel 7 Inn Anna
Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (442 reviews)
"The room was amazing clean and no problems "
United States
Javaneh
The price is €74
includes taxes & fees
31 May - 1 Jun
Town House Inn
Front of property – evening/night

Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (37 reviews)
"Jackie was amazing. She was very informative and helpful. Great communication. The room was really comfortable. And breakfast was great."
United States
Nicole
The price is €256
includes taxes & fees
1 Jun - 2 Jun
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Cape Girardeau attractions

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
Bill Emerson Memorial Bridge, Cape Girardeau, MO

Top Cape Girardeau Hotel Reviews

The Riverview

The Riverview

10/10 Excellent
"Great hotel, clean rooms, friendly staff, and a casino conveniently located where I could donate money to support the local economy. Had a fantastic time, even though the slot machines and I apparently had very different vacation plans. Would definitely stay again!"
Alexis 1-night trip
Posted 1 hour ago
The Riverview

More cheap stays in Cape Girardeau

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
The price is €65 per night from 7 Jun to 8 Jun
€65
7 Jun - 8 Jun
includes taxes & fees
7.2/10 Good! (746 reviews)

Frequently asked questions

What's the best place to stay in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and a restaurant. Other good options for your visit include The Riverview and Fairfield Inn & Suites by Marriott Cape Girardeau. See all available top hotels, or vacation rentals in Cape Girardeau.
What are some of the best holiday rentals that Cape Girardeau has to offer?
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: This highly rated holiday home rental in Cape Girardeau is equipped with a BBQ, air conditioning and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge and a stovetop. Other favourite homes for rent in Cape Girardeau are Serenity South -- Gardens, River-Views, and Refreshing Space and Little Blue Cottage on Spanish. See all vacation rentals in Cape Girardeau.
If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.
What's the best accommodation for a budget-friendly stay in Cape Girardeau?
Based on reviews, Pear Tree Inn Cape Girardeau West is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. View all budget hotels in Cape Girardeau.
What's the best family accommodation in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Pear Tree Inn Cape Girardeau West is another good option for your stay with the kids. Also, attractions such as Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are fun for children of all ages. Find more child-friendly accommodations in Cape Girardeau.
What's the best LGBTQ-friendly hotel in Cape Girardeau?
Pear Tree Inn Cape Girardeau Near the Medical Center is a top LGBTQ-friendly hotel, and features free Wi-Fi and LCD TVs. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.
What's the best dog-friendly hotel in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Candlewood Suites Cape Girardeau by IHG and Pear Tree Inn Cape Girardeau West. See more pet-friendly hotel accommodations in Cape Girardeau.
What are some accommodation options with pools in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa and free WiFi. View all hotels with pools in Cape Girardeau.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness centre. See all spa hotels in Cape Girardeau.
What is staying in Cape Girardeau like?
History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting and shopping. In Cape Girardeau, there are 63 hotels and other accommodation options to choose from. Find out more about Cape Girardeau.
What should I do while I'm visiting Cape Girardeau?
Favorite family attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. Landmarks like The Glenn House and Fort D Historic Site might be worth a visit. Natural beauty is on display at Shawnee National Forest, Mississippi River and Cape Rock Park. Take a look at what more there is to see and do in Expedia's Cape Girardeau guide.
What's the weather like in Cape Girardeau?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.

Explore a world of travel with Expedia