Photo by Ryan Coleman

Sikeston Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Sikeston hotels

Our top choices for Sikeston hotels

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (377)
"Great location and clean room. Plenty of food and shopping nearby."
The price is €103
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn Sikeston

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (740)
"Nice and clean hotel friendly service"
The price is €106
includes taxes & fees
5 Sept - 6 Sept
Hampton Inn Cape Girardeau I 55 East

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1004)
"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"
The price is €89
includes taxes & fees
4 Sept - 5 Sept
Drury Inn & Suites Sikeston, MO

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (603)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is €73
includes taxes & fees
31 Aug - 1 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Very nice property Friendly helpful staff"
The price is €76
includes taxes & fees
4 Sept - 5 Sept
Pear Tree Inn Sikeston

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1013)
"Very nice hotel and nice staff "
The price is €87
includes taxes & fees
2 Sept - 3 Sept
Drury Plaza Hotel Cape Girardeau Conference Center

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (500)
"Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! "
The price is €93
includes taxes & fees
31 Aug - 1 Sept
Holiday Inn Express & Suites Perryville by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very good, (670)
"Everything was nice"
The price is €59
includes taxes & fees
2 Sept - 3 Sept
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (125)
"The hotel was very clean and updated and the staff was super friendly and very informative!"
The price is €90
includes taxes & fees
4 Sept - 5 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (472)
"Rooms were clean and comfy, great breakfast "
The price is €99
includes taxes & fees
7 Sept - 8 Sept
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"The hotel was very nice and the staff were super helpful. I would stay here again!"
The price is €100
includes taxes & fees
14 Sept - 15 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (985)
"Easy access and parking"
The price is €87
includes taxes & fees
14 Sept - 15 Sept
Drury Inn & Suites Cape Girardeau

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (398)
"From the moment we walked in we were impressed with the customer service, facility & cleanliness. We enjoyed every part of our one night stay! We would definitely stay here again "
The price is €128
includes taxes & fees
14 Sept - 15 Sept
The Riverview

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Excellent place to stay "
The price is €68
includes taxes & fees
1 Sept - 2 Sept
Pear Tree Inn Cape Girardeau Near the Medical Center

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (424)
"Close in eating and shopping "
The price is €102
includes taxes & fees
12 Sept - 13 Sept
Holiday Inn Express & Suites Sikeston Southwest by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1006)
"We had a last minute reservation here. The staff was very pleasant, helpful and wonderful overall!!"
The price is €82
includes taxes & fees
7 Sept - 8 Sept
Drury Inn & Suites Jackson MO

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (441)
"Very clean and upscale hotel."
The price is €127
includes taxes & fees
28 Sept - 29 Sept
Courtyard by Marriott Cape Girardeau Downtown

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very good, (1003)
"Staff was friendly and room was very clean. A very comfortable stay"
The price is €82
includes taxes & fees
14 Sept - 15 Sept
Best Western Plus Sikeston

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very good, (900)
" Love the stay and staff was great "
The price is €71
includes taxes & fees
4 Sept - 5 Sept
Super 8 by Wyndham Perryville

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (56)
"Great overall stay"
The price is €99
includes taxes & fees
4 Sept - 5 Sept
Tru By Hilton Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Check out pet-friendly hotels in Sikeston

Hotels with free breakfast in Sikeston you'll enjoy

Hotels with a pool in Sikeston may fit your trip

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Sikeston and related destinations

Explore Sikeston: its dining, riverfront, museums and more!

Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

More cheap stays in Sikeston

More cheap stays in Sikeston

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best holiday rentals that Sikeston has to offer?

Beautiful location in the secluded woods : This holiday home rental outside of Sikeston offers a fireplace, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.

What's the best family accommodation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your family trip. Find more child-friendly accommodations in Sikeston.

What's the best LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best dog-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Best Western Plus Sikeston. See more pet-friendly hotel accommodations in Sikeston.

What are some hotels with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. TownePlace Suites by Marriott Sikeston is another choice with an on-site pool. View all hotels with pools in Sikeston.

What is staying in Sikeston like?

Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.

What is there to see in Sikeston?

A couple of favourite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Take a look at what more there is to see and do in Expedia's Sikeston guide.

What's the seasonal weather in Sikeston?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.