Hotels closest to Sikeston Depot Museum in Sikeston

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Our top choices for Sikeston Depot Museum hotels

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

1. Fairfield Inn & Suites by Marriott Sikeston

2.4 km from Sikeston Depot Museum

Allen

€100

includes taxes & fees

11 Oct - 12 Oct

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

2. TownePlace Suites by Marriott Sikeston

2.3 km from Sikeston Depot Museum

Stacy

€108

includes taxes & fees

8 Oct - 9 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

3. Hampton Inn Sikeston

2.3 km from Sikeston Depot Museum

John

€101

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A breakfast buffet area with a display of cinnamon sweet rolls, a sign indicating the roll selection, and a patterned wall in the background.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

2.1 km from Sikeston Depot Museum

Melissa

€100

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

5. Drury Inn & Suites Sikeston, MO

5.1 km from Sikeston Depot Museum

Scott

€95

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

6. Best Western Plus Sikeston I-55

5.4 km from Sikeston Depot Museum

Shelley

€86

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

5 km from Sikeston Depot Museum

Sharika West

€70

includes taxes & fees

29 Sept - 30 Sept

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A living room with two sofas, a coffee table, a TV, and a cabinet.

8. Comfort Inn & Suites Sikeston I-55

4.9 km from Sikeston Depot Museum

Starlette

€86

includes taxes & fees

29 Oct - 30 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

9. Days Inn and Suites by Wyndham Sikeston

5.4 km from Sikeston Depot Museum

David

€66

includes taxes & fees

1 Oct - 2 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

A reception area with a counter, a coffee machine, and seating.

10. Country Yard Inn and Suite

5.5 km from Sikeston Depot Museum

William

€64

includes taxes & fees

29 Sept - 30 Sept

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Compare popular hotels close to Sikeston Depot Museum

Property	Property class	Guest rating
Fairfield Inn & Suites by Marriott Sikeston	9.4 Exceptional 114 reviews	View
TownePlace Suites by Marriott Sikeston	9.4 Exceptional 26 reviews	View
Hampton Inn Sikeston	9.0 Wonderful 624 reviews	View
Holiday Inn Express & Suites Sikeston Southwest by IHG	8.8 Excellent 511 reviews	View
Drury Inn & Suites Sikeston, MO	9.6 Exceptional 1,002 reviews	View

Top Sikeston Depot Museum Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"NA NA NA NA NA NA NA NA NA NA NA NA NA"

Super 8 by Wyndham Charleston/Sikeston East MO

8/10 Good

"I have stayed there annually for 4 straight years to attend an event in nearby Sikeston. This year, for the first time, there was no couch or coffee table in my room, only a small computer desk and chair. I used to enjoy the small couch and table when watching TV and eating or using my laptop. I did not enjoy the extra empty space with no furniture. The receptionist said their removal was an "upgrade" and commented "We're doing it 'right' now..." whatever that means? Otherwise, I enjoyed my stay as usual. RB"

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent

"Everything was great clean helpful Everything friendly."

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."

Hampton Inn Sikeston

10/10 Excellent

"Staff was great"

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a very good value. It has been the best hotel I've stayed at in awhile."

TownePlace Suites by Marriott Sikeston

10/10 Excellent

"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

10/10 Excellent

"We had an excellent stay here. The host was very nice and make sure that we had everything we needed. If we come back here, we will definitely try to get this house again.Needless to say, we were very pleased with our day."

Eagle Inn Charleston

10/10 Excellent

"Great"

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Central Park

7.2/10 (56 reviews)

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City of Miner Convention Center

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Hunter-Dawson State Historic Site

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You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your trip to New Madrid. Amble around the area's parks or experience its museums.

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River Ridge Winery

8.4/10 (15 reviews)

You can enjoy a tasting or tour at River Ridge Winery during your travels to New Madrid. Amble around the area's parks or experience its museums.

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New Madrid Historical Museum

8.2/10 (36 reviews)

You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.

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Dexter Welcome Center Depot and Museum

7.6/10 (12 reviews)

You can study the exhibits at Dexter Welcome Center Depot and Museum, a museum with a story of its own, during your holiday in Dexter. While in this family-friendly area, you can enjoy the restaurants.

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The Heritage House

8.4/10 (7 reviews)

Learn about the local history of Dexter with a stop at The Heritage House. While in this family-friendly area, you can enjoy the restaurants.

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Frequently asked questions

What's the area like around Sikeston Depot Museum?

Sikeston Depot Museum is located in a welcoming area of Sikeston known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 5 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Sikeston Depot Museum?

Drury Inn & Suites Sikeston, MO is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. It's located 3.2 mi (5.1 km) from Sikeston Depot Museum. Other good choices within 5 miles include Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston.

How many hotels will I find close to Sikeston Depot Museum?

Expedia has 5 hotels and other accommodation options within a mile from Sikeston Depot Museum.

If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best options available near Sikeston Depot Museum.

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Our top choices for Sikeston Depot Museum hotels

1. Fairfield Inn & Suites by Marriott Sikeston