Sikeston

Travel Guide

Photo by Ryan Coleman
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
The price is €95 per night from 12 Dec to 13 Dec
€95
12 Dec - 13 Dec
includes taxes & fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,008 reviews)
The room was very clean. The front desk staff were courteous and helpful.

Reviewed on 9 Nov 2025

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is €62 per night from 17 Nov to 18 Nov
€62
17 Nov - 18 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,003 reviews)
Large property, great for dogs.

Reviewed on 7 Nov 2025

Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is €93 per night from 14 Dec to 15 Dec
€93
14 Dec - 15 Dec
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (423 reviews)
Very clean room, great staff, comfy bed, awesome shower! Breakfast was pretty good too.

Reviewed on 10 Nov 2025

Hampton Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Exquisite views of Shawnee National Forest seen from a private, covered hot tub.

Exquisite views of Shawnee National Forest seen from a private, covered hot tub.

Cobden
Stay at this cabin in Cobden. Enjoy free WiFi, a garden, and patios. Popular attractions Peachbarn Winery and Von Jakob Winery & Brewery are located nearby.
9.8/10 Exceptional! (39 reviews)
This cabin has the most stunning views! It was so nice to wake up and have breakfast while looking out the window and seeing the beautiful forest and the sky. The rooms were clean and tidy. I appreciate little things like having actual hand soap in the bathrooms. Thank you for a great weekend ...

Reviewed on 28 Oct 2025

Exquisite views of Shawnee National Forest seen from a private, covered hot tub.
On the Shawnee Wine Trail

On the Shawnee Wine Trail

Carbondale
Stay at this cabin in Carbondale. Enjoy patios, cable/satellite TV service, and an in-room coffeemaker. Popular attractions Cave Hollow Trailhead and Von Jakob ...
9.8/10 Exceptional! (225 reviews)
Hot tub was nice and easy to work. House had everything you would need for your stay. Only complaint the bed downstairs is firm and noisy and mattress upstairs is pretty firm. Great place to go for a walk with no traffic.

Reviewed on 14 Oct 2025

On the Shawnee Wine Trail
On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower

On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower

Alto Pass
Stay at this vacation home in Alto Pass. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Peachbarn Winery and Von Jakob Winery & Brewery ...
9.8/10 Exceptional! (170 reviews)
The host was very accommodating, fit us in last minute which gave us more time to see the sites. The beds were so comfy and the bathroom was a dream for a rental. Lots of room to spread out. The proximity to the Wine trail was a big plus after hiking all day we could visit close to our stay!

Reviewed on 28 Oct 2025

On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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