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Holiday Rentals in Cape Girardeau

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Holiday Rentals in Cape Girardeau

The Twisted Sassafras Treehouse

10.0 out of 10, Exceptional, (22)
"My wife and I thoroughly enjoyed our stay here! A beautiful place built on a beautiful property; we enjoyed the hot tub under the stars and the morning coffee on the porch (and another hot tub ). Great place for some R&R, and excellent communication with the owner in advance. Wouldn’t hesitate to book again."
The price is €293
includes taxes & fees
15 Sept - 16 Sept
The Twisted Sassafras Treehouse

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

9.6 out of 10, Exceptional, (40)
"Nice place to stay! Clean, able to walk to everything!"
The price is €131
includes taxes & fees
22 Sept - 23 Sept
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

10.0 out of 10, Exceptional, (219)
"This is our second time staying at the Kage House. Didnt disappoint at all. Great location! "
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (140)
"The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area."
The price is €212
includes taxes & fees
28 Sept - 29 Sept
Serenity South -- Gardens, River-Views, and Refreshing Space

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

8.6 out of 10, Excellent, (17)
"We stayed here with my cousins family while our daughters were playing at Sportplex. Nice and clean property. Host was easy to communicate with. Would stay here again when in this area. "
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

Gorgeous 1856 Log Cabin, Completely Renovated

10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
The price is €273
includes taxes & fees
31 Aug - 1 Sept
Gorgeous 1856 Log Cabin, Completely Renovated

Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable

10.0 out of 10, Exceptional, (1)
"Great location and the one issue was resolved quickly and no fault of the property owner. "
Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable

Charming Secluded Getaway Cabin within minutes of amenities

10.0 out of 10, Exceptional, (15)
"Nice little Cabin in a beautiful area. Blair and her family were wonderful!"
Charming Secluded Getaway Cabin within minutes of amenities

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.8 out of 10, Excellent, (33)
"all was so nice and we enjoyed our stay. grandkids and us loved having pool table and card games and all the peace and quiet there. thank u again for contacting me and giving us address. we appreciated that very much. "
The price is €252
includes taxes & fees
24 Sept - 25 Sept
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Little Blue Cottage on Spanish

8.6 out of 10, Excellent, (43)
"I would definitely stay here again!"
The price is €91
includes taxes & fees
31 Aug - 1 Sept
Little Blue Cottage on Spanish

Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

10.0 out of 10, Exceptional, (21)
"Lovely home perfect for our weekend celebrating our daughter’s graduation. Chip was an excellent host, even found us champagne flutes! Beds were comfortable, house was clean and nicely decorated. "
Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

Loft Apartment Across From Semo University Houch Field House. Walk To Events

10.0 out of 10, Exceptional, (90)
"This Vrbo was very clean and accurate to the listing. This was my second stay and it was amazing again the second time. "
The price is €160
includes taxes & fees
28 Sept - 29 Sept
Loft Apartment Across From Semo University Houch Field House. Walk To Events

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9.4 out of 10, Exceptional, (6)
"Great property would recommend 100%. We did not have to leave the house it had everything we needed for nine adult women to have a great streetlight"
The price is €459
includes taxes & fees
3 Sept - 4 Sept
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Quaint, Beautiful Home next to SEMO and Hospital

9.8 out of 10, Exceptional, (37)
"Quaint, little property with roomy accommodations. So much better than 4 people sharing a hotel room…everyone had their own space. The location was convenient, quiet and the neighborhood felt safe."
Quaint, Beautiful Home next to SEMO and Hospital

The Cottage, Rusted Route Farms

10.0 out of 10, Exceptional, (1)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
The price is €175
includes taxes & fees
31 Aug - 1 Sept
The Cottage, Rusted Route Farms

2Bdrm Stay in Downtown Cape, Walkable, Laundry

2Bdrm Stay in Downtown Cape, Walkable, Laundry

Peaceful secluded cabin located near Horseshoe Lake

9.8 out of 10, Exceptional, (17)
"This stay was comfortable and quiet an amazing weekend stay!!"
The price is €173
includes taxes & fees
8 Sept - 9 Sept
Peaceful secluded cabin located near Horseshoe Lake

New cabin in the woods with private hot tub

10.0 out of 10, Exceptional, (124)
"We absolutely love coming here. This was our 2nd stay and getting ready to book it for the fall again. "
New cabin in the woods with private hot tub

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

10.0 out of 10, Exceptional, (391)
"Gorgeous and comfortable property with front porch and back deck. "
The price is €177
includes taxes & fees
1 Sept - 2 Sept
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!

10.0 out of 10, Exceptional, (50)
"Had a great stay"
Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Find out more about Cape Girardeau

Find out more about Cape Girardeau

Everything you need to know about Cape Girardeau holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Cape Girardeau holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cape Girardeau holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Cape Girardeau holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Cape Girardeau. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Cape Girardeau holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Cape Girardeau holiday rentals we have selected for you start as low as €91 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Cape Girardeau rentals

At Expedia, we put the best Cape Girardeau holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Cape Girardeau rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cape Girardeau holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cape Girardeau. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find holiday rentals in Cape Girardeau?

Yes, there are holiday rentals in Cape Girardeau close to Cape Splash Family Aquatic Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your holiday.

What are some of the best holiday rentals that Cape Girardeau has to offer?

Serenity South -- Gardens, River-Views, and Refreshing Space: This highly rated holiday home rental in Cape Girardeau is located on a river, and has a fireplace, a balcony and air conditioning to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Cape Girardeau include 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool and Little Blue Cottage on Spanish.

How many holiday rentals will I find in Cape Girardeau?

Choose from 23 Expedia holiday rentals in Cape Girardeau for a memorable holiday.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are holiday rentals like in Cape Girardeau?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Cape Girardeau. Holiday rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a holiday rental can provide a sense of security away from public hotel lifts and busy front desks while still allowing you the experience of travel. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is an attractive choice for a small group gathering.