Rochester Hotel Guide. Hotels in East Side Pioneers, Rochester, United States of America

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Our top choices for East Side Pioneers hotels

Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
East Side Pioneers
8.8 out of 10, Excellent, (894)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is €78
includes taxes & fees
24 Jan - 25 Jan 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
East Side Pioneers
9.6 out of 10, Exceptional, (547)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is €168
includes taxes & fees
10 Jan - 11 Jan 2026
Hilton Rochester Mayo Clinic Area
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
East Side Pioneers
9.2 out of 10, Wonderful, (168)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is €154
includes taxes & fees
9 Jan - 10 Jan 2026
Broadway Plaza, Trademark Collection by Wyndham
Terrace/patio
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
3.3 km from East Side Pioneers
9.0 out of 10, Wonderful, (1001)
"We had a wonderful stay!"
United States
Sarah
The price is €79
includes taxes & fees
24 Jan - 25 Jan 2026
Hampton Inn Rochester-South
Exterior
Spark by Hilton Rochester South

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
7 km from East Side Pioneers
9.4 out of 10, Exceptional, (333)
"Very good accommodations at a wonderful price. "
United States
David
The price is €69
includes taxes & fees
11 Jan - 12 Jan 2026
Spark by Hilton Rochester South
Exterior
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
6.9 km from East Side Pioneers
8.8 out of 10, Excellent, (1000)
"Clean room, clean hotel, friendly staff Would stay here again."
United States
Chee
The price is €72
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Rochester South - Mayo Area by IHG
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.3 km from East Side Pioneers
7.2 out of 10, Good, (1027)
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is €70
includes taxes & fees
2 Jan - 3 Jan 2026
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 2.3 km from East Side Pioneers
9.4 out of 10, Exceptional, (971)
"The staff was very friendly and the room spotless. "
United States
Judith
The price is €113
includes taxes & fees
2 Jan - 3 Jan 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Indoor pool, open 7:00 AM to 11:00 PM, pool loungers
AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester
2.0 star property
12.2 km from East Side Pioneers
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay, rated breakfast as a erage as we did not try it."
United States
jeanne
AmericInn by Wyndham Rochester
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
3.4 km from East Side Pioneers
9.6 out of 10, Exceptional, (887)
"Great stay,clean and friendly"
United States
Janet
The price is €116
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area
Serves lunch, dinner and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
3 km from East Side Pioneers
8.2 out of 10, Very good, (1154)
"Check in was fast, room, and pool area were great, its connected to the crooked pint, making dining convenient. "
United States
Brian
The price is €73
includes taxes & fees
3 Jan - 4 Jan 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 1.3 km from East Side Pioneers
9.2 out of 10, Wonderful, (1008)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is €142
includes taxes & fees
24 Jan - 25 Jan 2026
Hyatt House Rochester/Mayo Clinic Area
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
3.8 km from East Side Pioneers
8.2 out of 10, Very good, (798)
"This hotel was"
United States
Sheila
The price is €92
includes taxes & fees
12 Jan - 13 Jan 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Exterior
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
8.2 km from East Side Pioneers
9.2 out of 10, Wonderful, (1000)
"Love room, breakfast, and shuttle to Mayo. We always stay there"
United States
Laureen
The price is €88
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Rochester-North
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 2.7 km from East Side Pioneers
9.2 out of 10, Wonderful, (773)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is €82
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park, 2.9 km from East Side Pioneers
8.8 out of 10, Excellent, (766)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is €107
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 1.1 km from East Side Pioneers
8.8 out of 10, Excellent, (856)
"Yes the workers are amazing "
United States
Luciana
The price is €105
includes taxes & fees
8 Jan - 9 Jan 2026
Hilton Garden Inn Rochester Downtown, MN
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 1.7 km from East Side Pioneers
9.6 out of 10, Exceptional, (483)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is €124
includes taxes & fees
10 Jan - 11 Jan 2026
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency, Upgrade)
Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
2.5 star property
6 km from East Side Pioneers
9.0 out of 10, Wonderful, (586)
"Nice place to stay "
United States
Melissa
The price is €79
includes taxes & fees
9 Jan - 10 Jan 2026
Sleep Inn & Suites West-Near Medical Center
Reception
America's Stay Inn Stewartville

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
17.5 km from East Side Pioneers
8.0 out of 10, Very good, (419)
"Room was nicer and furnished better than most high end places I’ve stayed at. It’s a small hotel on a busy road, but comfortable bed and clean."
Canada
Robert
America's Stay Inn Stewartville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Side Pioneers

Find the best East Side Pioneers areas for the activities you enjoy most.
Rochester showing skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Rochester which includes a river or creek and forest scenes
Photo by Chad Johnson
Open Photo by Chad Johnson

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

While Slatterly Park isn't home to many top sights, Rochester Art Center and Soldiers Field Veterans Memorial are some notable places to visit nearby.

Folwell

Though Folwell may not have many top sights, you can venture to the surrounding area to see attractions like Soldiers Field Veterans Memorial and Apache Mall.

Top East Side Pioneers Hotel Reviews

Spark by Hilton Rochester South

Spark by Hilton Rochester South

10/10 Excellent
"Very courteous staff and room is clean "
chris 1-night trip
Posted 2 days ago
Spark by Hilton Rochester South

Frequently asked questions

What's it like in East Side Pioneers?
Travellers are sure to enjoy a stay in Rochester's East Side Pioneers neighbourhood. Are you looking for East Side Pioneers travel tips? Make sure that you visit Rochester Art Center and Rochester Civic Theater while you're in the neighbourhood.
What's the best accommodation in East Side Pioneers?
Based on Expedia customer reviews, Hilton Rochester Mayo Clinic Area is the highest ranked property in East Side Pioneers. This hotel is a short 6-minute walk from Mayo Clinic, and it offers a full-service spa and 2 restaurants. Another favourite option in the neighbourhood is Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels should I expect to find in East Side Pioneers?
If you're searching for places to stay in Rochester, choose from one of Expedia's 17 hotels and other accommodation options in East Side Pioneers.
If I need to cancel my hotel reservation in East Side Pioneers, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals in East Side Pioneers.
What can I see and do in this Rochester neighbourhood?
Spend some time exploring the natural setting of East Side Pioneers with a visit to Silver Lake Park and Mayo Park. You could also plan a visit to Rochester Art Center or Rochester Civic Theater while you're in the neighbourhood. A few places to visit in the area around East Side Pioneers include Mayo Civic Center, Rochester Public Library and Shops University Square. While you're out sightseeing, Plummer Building and Soldiers Field Veterans Memorial are a couple of additional sights to visit in Rochester.