A tropical island with a beach, clear turquoise waters, and lush greenery.

Cheap Flights to Santa Isabel: Santa Isabel Flight Deals

View €185 flight on Wed, 6 Jan 2027Opens in a new window

Popular airlines to Santa Isabel

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Cheap round-trip flights to Santa Isabel

Prices were available within the past 7 days and start at €185 for one-way flights and €454 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
United
Copa
Aeromexico
American Airlines

Find the cheapest month to fly from Columbus (CMH) to Panama City (PTY)

From €524 - €712 per traveller.

Frequently asked questions

What is the name of Santa Isabel's airport?
Book a flight to Santa Isabel and you'll be landing at Tocumen Intl. Airport (PTY).
What airport is best to fly into Santa Isabel?
With one main airport servicing Santa Isabel, it won't take you long to find the best flight. You'll be taking off to Panama Airport, which is located around 56 kilometres from the centre of town.
How many airlines fly to Santa Isabel?
There are 14 airlines connecting Santa Isabel to 83 airports across the globe.
Which airlines fly to Santa Isabel?
Copa Airlines, Avianca and Turkish Airlines fly the most frequently to Santa Isabel. The majority of these flights originate in Bogotá, with Copa Airlines having the most services on this route.
How many nonstop flights are there to Santa Isabel?
Flying to a new place is much more straightforward when there aren't any annoying stopovers to slow you down. If you're jetting off to Santa Isabel, the great news is that there are 1,346 direct flights operating each week.
Where are the most popular flights to Santa Isabel departing from?
Flights to Santa Isabel from Bogotá, San José and Miami airports are very popular.
How long is the flight to Santa Isabel Airport?
If you're going to Santa Isabel from Bogotá, you'll have a flight time of 1 hour and 50 minutes. Those jetting off from San José can expect to be in the air for 1 hour and 23 minutes. From Miami it's roughly 3 hours and 10 minutes away.
How to book the cheapest flight to Santa Isabel?
If you want to save some cash on your trip to Santa Isabel, listen up! As every seasoned traveller will tell you, avoid booking at the last minute. Fares are generally more expensive just prior to the departure date. Another easy way to nab an unbeatable deal is to shop around. If your destination has more than one airport, be sure to look into the cost of flying into a less busy terminal. And finally, remember that the early bird catches the worm. Familiarise yourself with airfare costs and have your credit card ready to grab your ticket as soon as you spot an unbeatable bargain. The sweetest deals don't last long.
Do you have any tips for my flight to Santa Isabel?
Depending on where you're coming from, your trip to Santa Isabel could be no sweat at all or it could go on forever. We've compiled some useful tips that will help you start your next big adventure on the right foot. What to pack in your hand luggage:
  • A plane trip can be a cruisy experience if you take the right gear. Firstly, you'll want some basic toiletry items, such as a toothbrush and hairbrush, a clean pair of socks and a magazine or two. Next, find room in your hand luggage for your mobile phone, a charger, your medications and maybe a neck pillow too. Lastly, be sure to bring your passport, travel papers and some money.
Do not pack the following items in your hand luggage:
  • Leave all your full-sized bottles of hair gel and hairspray in your checked luggage. Any gels or liquids in your carry-on bag larger than 3.4 ounces (100 millilitres) will be confiscated by security. Sharp objects, like your treasured Swiss Army knife, and dangerous products which are flammable or explosive, such as aerosol cans, spray paint and poisons, are also banned.
What to wear on a flight:
  • The aisles of an aircraft aren't the place for a fashion parade. Layer your clothing and choose shoes that are flat, enclosed and easy to remove.
  • Deep vein thrombosis (DVT) is a risk on long-distance flights. It results from blood clots forming due to poor circulation, so do some gentle foot and leg exercises in your seat and consider wearing compression tights or socks.
How to get through airport security fast when flying to Santa Isabel?
Being prepared before you get to the airport will help make your getaway to Santa Isabel a pleasure. We've rounded up some handy tips and tricks for a stress-free journey through security:
  • Be sure to keep your passport and boarding pass someplace easily accessible. They'll be the first things you'll be asked to show at airport security.
  • The X-ray machine is up next. Empty your pockets and remove anything metal that is likely to beep. This includes things like headphones or earphones, as well as your coat or jacket. They'll all need to go on the X-ray conveyor belt.
  • Electronic devices like phones and laptops will also have to go through the machine to be scanned. Don't worry though, you'll be back online soon enough.
  • Want to bring along your favourite perfume or cologne? Not a problem. As long as the volume is no larger than 3.4 ounces (100 millilitres) and it's stored in a clear zip-close bag, you can keep it with you on board.
  • The right choice of footwear can save you valuable minutes. Boots and heavy shoes are often required to be removed and separately scanned. Slip-on shoes are usually not.
  • Sharp items such as knives and scissors can't be taken on board. They'll be seized at security, so pack them in your checked luggage.

Book with confidence

Expedia.ie is an online travel company that specialises in securing the best prices for flights to Santa Isabel. With Expedia you get highly specialised services, combining the best of technology, in-depth knowledge and the best connections in order to offer great deals to Santa Isabel. Expedia shares your passion for travel and has built the best online travel service that promotes and encourages travel. Whether you are looking for cheap flights to Santa Isabel, or are just on the lookout for the best flights to Santa Isabel, you are sure to find the best deals with Expedia.ie.

"One of the many benefits of booking your flights through Expedia is that we are one of the world’s largest online travel agency, which means we use our collective experience and work tirelessly to bring you the best prices. With Expedia you get a user-friendly internet experience and a dedicated customer support service that ensures that everything goes smoothly. The goal of Expedia is to offer premium services at the lowest price, all at one single place. If you wish to save even more try combing a hotel in Santa Isabel to your flight and create a personalised low cost city break or holiday to your favourite destination. Book early and you could save even more!

If you have an Expedia.ie itinerary number and have a question or concern about your travel plans you can call us on (01) 524 5005 from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends and an Expedia agent will help you.

Travel information

Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Destination city name
Panama City
Return price
€453

Trending flights to Santa Isabel

Prices were available within the past 7 days and start at €185 for one-way flights and €454 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
*Available to Expedia members.