Cheap flights to Panama

View €293 flight on Thu, 19 Mar 2026Opens in a new window

Popular airlines to Panama

  • American Airlines

  • Avianca

  • United

  • Delta

  • Copa

  • Aeromexico

  • KLM

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Cheap round-trip flights to Panama

Prices were available within the past 7 days and start at €293 for one-way flights and €553 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Iberia
Fri, 8 May - Sun, 24 May
MAD
Madrid
PTY
Panama City
€553 Return, found 20 hours ago
€553
Return
found 20 hours ago
Select Iberia flight, departing Fri, 8 May from Madrid to Panama City, returning Sun, 24 May, priced at €553 found 20 hours ago
Air Europa
Wed, 22 Apr - Sun, 3 May
MAD
Madrid
PTY
Panama City
€593 Return, found 5 days ago
€593
Return
found 5 days ago
Select Air Europa flight, departing Wed, 22 Apr from Madrid to Panama City, returning Sun, 3 May, priced at €593 found 5 days ago
Air Europa
Fri, 8 May - Sun, 24 May
MAD
Madrid
PTY
Panama City
€593 Return, found 20 hours ago
€593
Return
found 20 hours ago
Select Air Europa flight, departing Fri, 8 May from Madrid to Panama City, returning Sun, 24 May, priced at €593 found 20 hours ago
Air Europa
Tue, 16 Jun - Wed, 24 Jun
MAD
Madrid
PTY
Panama City
€623 Return, found 1 day ago
€623
Return
found 1 day ago
Select Air Europa flight, departing Tue, 16 Jun from Madrid to Panama City, returning Wed, 24 Jun, priced at €623 found 1 day ago
Iberia
Wed, 13 May - Wed, 27 May
MAD
Madrid
PTY
Panama City
€643 Return, found 5 days ago
€643
Return
found 5 days ago
Select Iberia flight, departing Wed, 13 May from Madrid to Panama City, returning Wed, 27 May, priced at €643 found 5 days ago
Iberia
Fri, 15 May - Fri, 22 May
MAD
Madrid
PTY
Panama City
€643 Return, found 3 days ago
€643
Return
found 3 days ago
Select Iberia flight, departing Fri, 15 May from Madrid to Panama City, returning Fri, 22 May, priced at €643 found 3 days ago
Air Europa
Fri, 19 Jun - Tue, 30 Jun
MAD
Madrid
PTY
Panama City
€653 Return, found 5 days ago
€653
Return
found 5 days ago
Select Air Europa flight, departing Fri, 19 Jun from Madrid to Panama City, returning Tue, 30 Jun, priced at €653 found 5 days ago
avianca
Wed, 13 May - Wed, 27 May
MAD
Madrid
PTY
Panama City
€657 Return, found 5 days ago
€657
Return
found 5 days ago
Select avianca flight, departing Wed, 13 May from Madrid to Panama City, returning Wed, 27 May, priced at €657 found 5 days ago
KLM
Mon, 28 Sept - Tue, 20 Oct
MAD
Madrid
PTY
Panama City
€700 Return, found 6 days ago
€700
Return
found 6 days ago
Select KLM flight, departing Mon, 28 Sept from Madrid to Panama City, returning Tue, 20 Oct, priced at €700 found 6 days ago
Swiss International Air Lines
Fri, 12 Jun - Sun, 28 Jun
DUB
Dublin
PTY
Panama City
€728 Return, found 6 days ago
€728
Return
found 6 days ago
Select Swiss International Air Lines flight, departing Fri, 12 Jun from Dublin to Panama City, returning Sun, 28 Jun, priced at €728 found 6 days ago

Trending flights to Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Swiss International Air Lines
Fri, 12 Jun - Sun, 28 Jun
DUB
Dublin
PTY
Panama City
€728 Return, found 6 days ago
€728
Return
found 6 days ago
Select Swiss International Air Lines flight, departing Fri, 12 Jun from Dublin to Panama City, returning Sun, 28 Jun, priced at €728 found 6 days ago

Frequently asked questions

How do I find cheap flights to Panama that have flexible change policies?
By using our clever "No change fee" filter, that's how. All you have to do is enter your origin, destination and dates, click the "Search" button, then click the checkbox directly below the "Flexible change policies" heading (left-hand side of your screen). Expedia makes it a snap to find inexpensive, flexible airfares to Panama.
Which airlines fly to Panama?
You can choose from a good variety of airlines with flights into or near Panama. A few of your options are:

  • Copa Airlines - 772 flights to or near Panama each month, including 772 flights to Tocumen Intl. Airport (PTY) per month.
  • United Airlines - 91 flights to or near Panama each month, including 91 flights to Tocumen Intl. Airport (PTY) per month.
  • American Airlines - 60 flights to or near Panama each month, including 60 flights to Tocumen Intl. Airport (PTY) per month.

How can I find cheap tickets to Panama?
In the last seven days, €553 was the best price for a flight to Panama. For even greater savings, book well ahead of time and be flexible with your travel dates. Search for your trip to Panama, then see prices for nearby days by clicking on our "flexible dates" link.
How much is a flight to Panama?
You could have scored a round-trip flight to Panama from anywhere between €553 and €728 in the last seven days. For one-way journeys departing from Madrid (MAD), the lowest price during this period was just €293.
What are the most popular airports to fly into in Panama?
Panama's main entryway is Tocumen Intl. Airport (PTY). Get your awesome journey underway by booking a ticket on one of the 963 flights every month to this destination.
How much is a plane ticket to Panama?
In the last seven days, plane fares to Panama ranged from €553 to €728.
What is the best time to go to Panama?
San Miguelito, Panama's most well-known city, is a superb location to check out at anytime. Not into the cold? Then head here from June 20 onward in summer, when temperatures fluctuate from 24ºC to 29ºC. February, March and May is when San Miguelito attracts the biggest crowds.
What months are the cheapest to book a flight to Panama?
To score a fabulous deal to Panama, book sometime in February when the prices are at their cheapest. When's the most expensive time? In the U.S, it's December.

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About Panama

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About Panama

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