A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

5 Star Hotels in Panama City, Panamá Province

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Check availability on Panama City 5 Star Hotels

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Panama City 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern hotel room with a dining area, a TV, and a city view.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Caroline
€130
includes taxes & fees
21 Oct - 22 Oct
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
€258
includes taxes & fees
31 Oct - 1 Nov
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
€345
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
€133
includes taxes & fees
31 Oct - 1 Nov
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A terrace with seating and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Detra Dorsey
€274
includes taxes & fees
7 Nov - 8 Nov
JW Marriott Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A modern interior with a central seating area, potted plants, and a staircase.

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Mariah
€184
includes taxes & fees
18 Oct - 19 Oct
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A pool with a central water feature, surrounded by seating areas and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Carmen
€272
includes taxes & fees
1 Nov - 2 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

8. W Panama

W Panama
Bella Vista
United States
Naomi
€227
includes taxes & fees
1 Nov - 2 Nov
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern bar area with seating and a view of the city.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern interior with a spiral staircase, a large window, and a seating area.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Simon
€241
includes taxes & fees
6 Nov - 7 Nov
Hilton Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A beachfront hotel with a large building, a beach, and a clear sky.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Anna
€202
includes taxes & fees
25 Oct - 26 Oct
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A person performing a yoga pose in a living room with a large window and a sofa.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
€245
includes taxes & fees
17 Oct - 18 Oct
Bristol Panama, a Registry Collection Hotel
Lobby
Breakfast area
Outdoor pool
Banquet hall

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
€101
includes taxes & fees
3 Nov - 4 Nov
Waymore Hotel Spa and Casino
Terrace/patio
Room
Casino
Outdoor spa tub

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
€138
10 Nov - 11 Nov
includes taxes & fees
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
€219
9 Nov - 10 Nov
includes taxes & fees
9/10 Wonderful! (1,014 reviews)
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
€133
31 Oct - 1 Nov
includes taxes & fees
Megapolis Hotel Panamá
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"Exactly what you would expect from hyatt resort"
Nehemiah 3-night trip
Posted 8 hours ago
Hyatt Regency Panama City
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"N/A"
Rhonda 3-night trip
Posted 9 hours ago
JW Marriott Panama

Frequently asked questions

What are the best 5-star hotels in Panama City?
Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are some of the top 5-star hotels in Panama City, based on our guest reviews. These deluxe hotels rate highly for things such as their location, amenities and service standards. Pick your favourite and enjoy the best of it all.
How much does it cost to stay in a 5-star hotel in Panama City?
The amount you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to find the best rate on a plush stay.
  • Search for the lowest price per night from €133
What makes a hotel 5 stars in Panama City?
In Panama City, a hotel needs to offer a certain level of high-end conveniences to earn 5 stars. These can include gourmet restaurants, on-site gyms, saunas and spas, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their exceptional standard of service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may even offer extra touches like a welcome gift.

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