5 Star Hotels in Panama City, Panamá Province
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama City 5 Star Hotels
Tonight
27 Aug - 28 AugTomorrow
28 Aug - 29 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sept - 6 SeptOur top choices for Panama City 5-star hotels
€125
includes taxes & fees
28 Sept - 29 Sept
€251
includes taxes & fees
30 Aug - 31 Aug
€340
includes taxes & fees
19 Sept - 20 Sept
4. Renaissance Panama City Hotel
Renaissance Panama City HotelBella Vista
Tad Olivet Ottinger Welcome
€120
includes taxes & fees
2 Sept - 3 Sept
€195
includes taxes & fees
15 Sept - 16 Sept
6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama CityJuan Diaz
Maria Adriana Bravo
€254
includes taxes & fees
3 Sept - 4 Sept
€248
includes taxes & fees
20 Sept - 21 Sept
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
€125
27 Sept - 28 Sept
includes taxes & fees
8.6/10 Excellent! (2,724 reviews)
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
€173
27 Sept - 28 Sept
includes taxes & fees
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
€104
29 Aug - 30 Aug
includes taxes & fees
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Panama City
The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.
See all hotels in Panama City
Top Panama City Hotel Reviews
Hotel Riu Plaza Panama
8/10 Good
"Not at this time"
Renaissance Panama City Hotel
10/10 Excellent
"I was very satisfied"
Waldorf Astoria Panama
10/10 Excellent
"Dede el ingress estuvimos super bien recibidos hasta el check in y en lahabitacion super bien el de say unto muy recommendable y gran atencion"
Frequently asked questions
What are the best 5-star hotels in Panama City?
Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are some of the top 5-star hotels in Panama City, based on our guest reviews. These deluxe hotels rate highly for things such as their location, amenities and service standards. Pick your favourite and enjoy the best of it all.
How much does it cost to stay in a 5-star hotel in Panama City?
The amount you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to find the best rate on a plush stay.
- Search for the lowest price per night from €104
What makes a hotel 5 stars in Panama City?
In Panama City, a hotel needs to offer a certain level of high-end conveniences to earn 5 stars. These can include gourmet restaurants, on-site gyms, saunas and spas, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their exceptional standard of service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may even offer extra touches like a welcome gift.
Explore a world of travel with Expedia
- 3 Star Hotels in Panama City
- 4 Star Hotels in Panama City
- 5 Star Hotels in Costa del Este
- Hotels near ATLAPA Conventions Center
- Beach Hotels in Bella Vista
- Bella Vista Hotels
- Bethania Hotels
- Calidonia Hotels
- Boutique Hotels in Casco Viejo
- Casino Hotels in Casco Viejo
- Wedding Hotels in Casco Viejo
- Casco Viejo Hotels
- Hotels near Cinta Costera
- Hotels near Club de Clases y Tropas
- Panamá Province Hotels
- Casino Hotels in El Cangrejo
- Hotels with Bar in El Cangrejo
- Lgbt-Friendly Hotels in El Cangrejo
- Hotels with Spa in El Cangrejo
- El Cangrejo Hotels
- Avalon Resorts in Marbella
- Hilton Hotels in Marbella
- Marbella Hotels
- Hotels near Marcos A. Gelabert Intl.
- Aparthotels in Panama City
- Apartments in Panama City
- B&B in Panama City
- Condo Rentals in Panama City
- Hostels in Panama City
- All Inclusive Hotels in Panama City
- Boutique Hotels in Panama City
- Casino Hotels in Panama City
- Hotels with Bar in Panama City
- Hotels with Restaurant in Panama City
- Hotels with Pool in Panama City
- Lgbt-Friendly Hotels in Panama City
- Luxury Hotels in Panama City
- Pet Friendly Hotels in Panama City
- Hotels with Spa in Panama City
- Wedding Hotels in Panama City
- Panama City Hotels
- Hostels in Panamá Province
- Punta Pacifica Hotels
- Casino Hotels in San Francisco
- Flights to Panama City
- Flights from Marcos A. Gelabert Intl.
- Flights from Aioun el Atrouss (AEO) to Panama City (PAC)
- Flights from Aniwa Island (AWD) to Panama City (PAC)
- Flights from The Valley (AXA) to Panama City (PAC)
- Flights from Bikini (BII) to Panama City (PAC)
- Flights from Bogotá (BOG) to Panama City (PAC)
- Flights from Bamenda (BPC) to Panama City (PAC)
- Flights from Akron (CAK) to Panama City (PAC)
- Flights from Paris (CDG) to Panama City (PAC)
- Flights from Clermont-Ferrand (CFE) to Panama City (PAC)
- Flights from Chambery (CMF) to Panama City (PAC)
- Flights from Delhi (DEL) to Panama City (PAC)
- Flights from Saint-Etienne (EBU) to Panama City (PAC)
- Flights from Fort Pierce (FPR) to Panama City (PAC)
- Flights from Gore (GOR) to Panama City (PAC)
- Flights from Gatokae (GTA) to Panama City (PAC)
- Flights from Haikou (HAK) to Panama City (PAC)
- Flights from Xalapa (JAL) to Panama City (PAC)
- Flights from New York (JFK) to Panama City (PAC)
- Flights from Kiffa (KFA) to Panama City (PAC)
- Flights from Kayes (KYS) to Panama City (PAC)
- Flights from Macon (MCN) to Panama City (PAC)
- Flights from Medellín (MDE) to Panama City (PAC)
- Flights from Miami (MIA) to Panama City (PAC)
- Flights from Morelia (MLM) to Panama City (PAC)
- Flights from Chicago (ORD) to Panama City (PAC)
- Flights from Phoenix (PHX) to Panama City (PAC)
- Flights from Resende (REZ) to Panama City (PAC)
- Flights from London (SEN) to Panama City (PAC)
- Flights from San José del Cabo (SJD) to Panama City (PAC)
- Flights from Santa Cruz de Tenerife (TFN) to Panama City (PAC)
- Flights from Uberlandia (UDI) to Panama City (PAC)
- Flights from Yap (YAP) to Panama City (PAC)
- Flights from Geraldton (YGQ) to Panama City (PAC)
- Flights from Wemindji (YNC) to Panama City (PAC)
- Flights from Bella Bella (ZEL) to Panama City (PAC)
- Flights from Nanaimo (ZNA) to Panama City (PAC)