5 Star Hotels in Panama City, Panamá Province
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama City 5 Star Hotels
Our top choices for Panama City 5-star hotels
9.0 out of 10, Wonderful, (5,306 reviews)
"Great place to stay, great staff, I had a good time in the hotel itself "
Walana
The price is €129
includes taxes & fees
5 May - 6 May
9.0 out of 10, Wonderful, (1,002 reviews)
"Excellent hotel, staff, and re"
Joseph
The price is €241
includes taxes & fees
24 Apr - 25 Apr
9.6 out of 10, Exceptional, (256 reviews)
"Great staff and the food was amazing. "
Nyrisha
The price is €147
includes taxes & fees
6 May - 7 May
9.0 out of 10, Wonderful, (1,025 reviews)
"Very enjoyable stay"
Lynnette
The price is €239
includes taxes & fees
2 May - 3 May
8.8 out of 10, Excellent, (186 reviews)
"Very good hotel, well located. "
Andrés
The price is €119
includes taxes & fees
28 Apr - 29 Apr
8.0 out of 10, Very good, (1,019 reviews)
"nice hotel, quality food, friendly staff, nice pools. "
christopher
The price is €188
includes taxes & fees
30 Apr - 1 May
9.8 out of 10, Exceptional, (631 reviews)
"Had a lovely stay"
Olly
The price is €332
includes taxes & fees
26 Apr - 27 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is €124 per night from 10 May to 11 May
€124
per night
10 May - 11 May
8.6/10 Excellent! (2,512 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Panama City
The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.
Top Panama City Hotel Reviews
Hotel Riu Plaza Panama
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- 3 Star Hotels in Panama City
- 4 Star Hotels in Panama City
- 5 Star Hotels in Costa del Este
- Hotels near ATLAPA Conventions Center
- Beach Hotels in Bella Vista
- Bella Vista Hotels
- Bethania Hotels
- Calidonia Hotels
- Boutique Hotels in Casco Viejo
- Casino Hotels in Casco Viejo
- Wedding Hotels in Casco Viejo
- Casco Viejo Hotels
- Hotels near Cinta Costera
- Hotels near Club de Clases y Tropas
- Panamá Province Hotels
- Casino Hotels in El Cangrejo
- Hotels with Bar in El Cangrejo
- Lgbt-Friendly Hotels in El Cangrejo
- Hotels with Spa in El Cangrejo
- El Cangrejo Hotels
- Avalon Resorts in Marbella
- Hilton Hotels in Marbella
- Marbella Hotels
- Hotels near Marcos A. Gelabert Intl.
- Aparthotels in Panama City
- Apartments in Panama City
- B&B in Panama City
- Condo Rentals in Panama City
- Hostels in Panama City
- All Inclusive Hotels in Panama City
- Boutique Hotels in Panama City
- Casino Hotels in Panama City
- Hotels with Bar in Panama City
- Hotels with Restaurant in Panama City
- Hotels with Pool in Panama City
- Lgbt-Friendly Hotels in Panama City
- Luxury Hotels in Panama City
- Pet Friendly Hotels in Panama City
- Hotels with Spa in Panama City
- Wedding Hotels in Panama City
- Panama City Hotels
- Hostels in Panamá Province
- Punta Pacifica Hotels
- Casino Hotels in San Francisco
- Flights to Panama City
- Flights from Marcos A. Gelabert Intl.
- Flights from Aioun el Atrouss (AEO) to Panama City (PAC)
- Flights from Aniwa Island (AWD) to Panama City (PAC)
- Flights from The Valley (AXA) to Panama City (PAC)
- Flights from Bikini (BII) to Panama City (PAC)
- Flights from Bogotá (BOG) to Panama City (PAC)
- Flights from Bamenda (BPC) to Panama City (PAC)
- Flights from Akron (CAK) to Panama City (PAC)
- Flights from Paris (CDG) to Panama City (PAC)
- Flights from Clermont-Ferrand (CFE) to Panama City (PAC)
- Flights from Chambery (CMF) to Panama City (PAC)
- Flights from Delhi (DEL) to Panama City (PAC)
- Flights from Saint-Etienne (EBU) to Panama City (PAC)
- Flights from Fort Pierce (FPR) to Panama City (PAC)
- Flights from Gore (GOR) to Panama City (PAC)
- Flights from Gatokae (GTA) to Panama City (PAC)
- Flights from Haikou (HAK) to Panama City (PAC)
- Flights from Xalapa (JAL) to Panama City (PAC)
- Flights from New York (JFK) to Panama City (PAC)
- Flights from Kiffa (KFA) to Panama City (PAC)
- Flights from Kayes (KYS) to Panama City (PAC)
- Flights from Macon (MCN) to Panama City (PAC)
- Flights from Medellín (MDE) to Panama City (PAC)
- Flights from Miami (MIA) to Panama City (PAC)
- Flights from Morelia (MLM) to Panama City (PAC)
- Flights from Chicago (ORD) to Panama City (PAC)
- Flights from Phoenix (PHX) to Panama City (PAC)
- Flights from Resende (REZ) to Panama City (PAC)
- Flights from London (SEN) to Panama City (PAC)
- Flights from San José del Cabo (SJD) to Panama City (PAC)
- Flights from Santa Cruz de Tenerife (TFN) to Panama City (PAC)
- Flights from Uberlandia (UDI) to Panama City (PAC)
- Flights from Yap (YAP) to Panama City (PAC)
- Flights from Geraldton (YGQ) to Panama City (PAC)
- Flights from Wemindji (YNC) to Panama City (PAC)
- Flights from Bella Bella (ZEL) to Panama City (PAC)
- Flights from Nanaimo (ZNA) to Panama City (PAC)