Panama City Holidays

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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Top hotels in Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is €103 per night from 8 Sept to 9 Sept
€103
8 Sept - 9 Sept
includes taxes & fees
9/10 Wonderful! (4,200 reviews)
"Excelente Hotel en todos sus aspectos."

Reviewed on 25 Aug 2025

Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is €76 per night from 31 Aug to 1 Sept
€76
31 Aug - 1 Sept
includes taxes & fees
Waymore Hotel Spa & Casino
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is €126 per night from 7 Sept to 8 Sept
€126
7 Sept - 8 Sept
includes taxes & fees
Sheraton Grand Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Panama City

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.