Panama City Holidays

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to €185 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
Default Image

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Top hotels in Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is €102 per night from 26 Aug to 27 Aug
€102
26 Aug - 27 Aug
includes taxes & fees
9/10 Wonderful! (4,188 reviews)
Great stay
"This hotel gave me one of the most luxurious hotel experiences I’ve ever had. It is centrally located with easy access to all your daily social and business needs. The room was brilliantly designed to ensure for the customer luxury feel, comfort, convenience, and ample space. The staff were very ..."

Reviewed on 23 Aug 2025

Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is €76 per night from 24 Aug to 25 Aug
€76
24 Aug - 25 Aug
includes taxes & fees
9/10 Wonderful! (424 reviews)
"The Superior room was awesome"

Reviewed on 21 Aug 2025

Waymore Hotel Spa & Casino
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is €126 per night from 1 Sept to 2 Sept
€126
1 Sept - 2 Sept
includes taxes & fees
8.4/10 Very Good! (932 reviews)
"Everyone was very nice and accommodating. The staff was primarily bilingual, offered to help with anything needed, and offered water bottles as part of the service."

Reviewed on 21 Aug 2025

Sheraton Grand Panama
See all 1,453 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Panama City

Slingshot Tour Panama

Slingshot Tour Panama

€100
per adult
76% of travellers recommend
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

€129
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

€28
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City

Frequently asked questions

How much does a Panama City holiday package cost?
You can pick up a holiday package to this destination on Expedia. However, how much your holiday to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
You're likely to find lower rates and better availability in September, October and November. Take a look at our cheap Panama City holiday packages and you could get some great off-season discounts.
How many days is enough for Panama City?
Dedicate around 3 days for your Panama City holiday in order to discover everything that makes this destination special. Stroll around popular areas, including San Francisco and Campo Alegre. Then check out major sights such as Metropolitan Cathedral of Panama and National Theatre. With a good itinerary, you can keep busy with room for some rest time too. Want to travel beyond Panama City? Consider squeezing in an excursion or two.
Is it worth booking a holiday package to Panama City?
Popular for its nature, nightlife and culture, a Panama City holiday is a hit with all types of travellers. Be sure to visit leading sights like Albrook Shopping Mall and Cinta Costera, and consider renting a car for day trips to explore even more.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveller experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider travelling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City holiday as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalised holiday package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a holiday package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?

  1. Choose when to go: Check your schedule and get your bags packed. Your preferred time of year and the available activities will also help you decide when to visit Panama City.
  2. Plan your budget wisely: As well as the cost of your stay, you'll need to factor in other expenses too. These include food, flights and transportation. Also, put aside a little extra for unexpected costs that could arise during your trip to Panama City.
  3. Work out your trip length: Think about how long you want to spend exploring Panama City. Plan your itinerary so you can get to all the attractions and activities you're interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customised Panama City holiday package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.