A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City Hotel Guide - Luxury Hotels in Panama City, Panamá Province

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Panama City Luxury Hotels

Tonight
10 Sept - 11 Sept
Tomorrow
11 Sept - 12 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Our top choices for Panama City luxury hotels

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
€387
includes taxes & fees
20 Sept - 21 Sept
Sofitel Legend Casco Viejo, Panama City

2. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
€264
includes taxes & fees
9 Oct - 10 Oct
Hotel La Compañía Casco Antiguo

3. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
€256
includes taxes & fees
26 Sept - 27 Sept
JW Marriott Panama

4. W Panama

W Panama
Bella Vista
  • Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
€211
includes taxes & fees
11 Oct - 12 Oct
W Panama

5. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
€239
includes taxes & fees
1 Oct - 2 Oct
Dreams Playa Bonita Panama - All Inclusive

6. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
  • Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
€252
includes taxes & fees
27 Sept - 28 Sept
Waldorf Astoria Panama

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
€254
includes taxes & fees
1 Oct - 2 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

8. Hilton Panama

Hilton Panama
Bella Vista
  • Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
€219
includes taxes & fees
3 Oct - 4 Oct
Hilton Panama

9. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
€173
includes taxes & fees
11 Oct - 12 Oct
Central Hotel Panama Casco Viejo

10. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
  • Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
€177
includes taxes & fees
19 Sept - 20 Sept
Hyatt Regency Panama City
View all properties

Find out more about Panama City

Panama Cityand its attractions for luxury travelers

For a luxurious escape in Panama City, indulge in the vibrant atmosphere of the Casco Viejo district, where historic architecture meets modern sophistication. Explore the beautifully restored historic buildings and enjoy fine dining at Michelin-starred restaurants like Manolo Caracol, offering a unique twist on traditional Panamanian cuisine. A stroll along the Amador Causeway provides stunning views of the Pacific Ocean and the iconic Panama City skyline, ideal for sunset cocktails at swanky rooftop bars like the Sky Bar at the Waldorf Astoria. Don’t miss the opportunity to visit the Panama Canal, where you can take a private yacht tour for an exclusive look at this engineering marvel while enjoying gourmet refreshments. For shopping enthusiasts, the upscale Multiplaza Pacific Mall offers high-end brands and bespoke boutiques, perfect for a day of indulgent retail therapy. Staying in the affluent Punta Pacifica area positions you in nearby top-tier hotels such as the JW Marriott Panama, where you can expect exceptional service, opulent amenities, and a serene, luxurious feel that caters to your every need, ensuring a truly pampered experience.

Find the best luxury hotels and resorts in Panama City

For those seeking an indulgent escape in Panama City, these luxurious hotels offer exceptional amenities and unparalleled service, ensuring a memorable stay for travelers.Plaza Paitilla Inn Hotel

  • Why it's great for a luxury retreat: With a stellar review rating of 9.4, the Plaza Paitilla Inn Hotel is a sophisticated choice for luxury seekers. This hotel captivates guests with its premium bedding and air-conditioned rooms, ensuring a restful stay. The popular / top / much-loved onsite spa offers relaxing treatments, including reflexology and Swedish massages, making it a haven for rejuvenation.
  • Other amenities: Guests can enjoy the outdoor pool with sun loungers, as well as a terrace perfect for unwinding. The hotel also provides secured valet parking, a delicious complimentary buffet breakfast, and various shopping options onsite. With early check-in and late check-out available, this hotel prioritises the convenience and comfort of its guests.
  • Neighborhood: Punta Paitilla
  • Nearby attractions: Avenida Balboa - 0.5 km, Cinta Costera - 0.8 km, Multicentro Panama - 1.4 km

Plaza Paitilla Inn Hotel

  • Why it's great for a luxury retreat: With an exceptional traveler review rating of 9.4, Plaza Paitilla Inn Hotel provides a luxurious experience that is both welcoming and relaxing. This upscale hotel features premium bedding and a secured valet parking service, ensuring that travelers feel pampered from the moment they arrive. The outdoor pool area is perfect for unwinding, while the hotel's spa offers a range of treatments for an indulgent experience.
  • Other amenities: Guests can enjoy a complimentary buffet breakfast each morning, along with an array of spa services including reflexology and Swedish massages. The hotel also features a terrace for relaxation, and various shopping options onsite for those looking to indulge during their stay. Fitness facilities and pool umbrellas add to the comfort, making this hotel a splendid spot for luxury seekers.
  • Neighborhood: Punta Paitilla
  • Nearby attractions: Avenida Balboa - 0.5 km, Cinta Costera - 0.8 km, Multicentro Panama - 1.4 km

Bristol Panama, a Registry Collection Hotel

  • Why it's great for a luxury retreat: Bristol Panama stands out with its remarkable traveler review rating of 9.2, showcasing an exquisite blend of luxury and sophistication. This hotel features an onsite art gallery, providing a unique cultural experience for travelers. The luxurious amenities include designer toiletries, bathrobes, and premium bedding, ensuring a restful and opulent stay. Valet parking and concierge services further enhance the level of service offered to travelers.
  • Other amenities: Additional features include a 24-hour room service, a spa complete with steam rooms and treatment areas, and an outdoor pool for relaxation. Guests can also enjoy a terrace, fitness facilities, and various dining options, including couples dining. The hotel’s strategic location in Bella Vista offers easy access to local attractions, making it a top choice for luxury travellers.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 0.6 km, Calle 50 - 0.7 km, Avenida Balboa - 0.7 km

Hotel Riu Plaza Panama

  • Why it's great for a luxury retreat: The Hotel Riu Plaza Panama stands out as a premier choice for luxury travelers, an impressive guest review rating of 9.0. Guests can enjoy refined amenities such as a Club Level Lounge providing complimentary refreshments and an outdoor pool for relaxation under the sun. The hotel’s concierge service further enhances the experience, ensuring every need is met with elegance and efficiency.
  • Other amenities: This upscale hotel features valet parking, an onsite shopping district, and a spa with treatment rooms for ultimate relaxation. Guests can indulge in a delightful buffet breakfast daily, while the poolside bar offers a perfect spot for refreshing drinks. With air conditioning and premium bedding, comfort is paramount in every room, making it an ideal retreat for luxury-seeking guests.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 1.5 km, Calle 50 - 0 km, Via Espana - 1 km

Hotel Riu Plaza Panama

  • Why it's great for a luxury retreat: Hotel Riu Plaza Panama is a pinnacle of luxury, featuring an impressive traveler review rating of 9.0. This hotel offers an array of upscale amenities, including a Club Level Room with exclusive lounge access, valet parking, and a refreshing outdoor pool complemented by a poolside bar. Guests can indulge in the convenience of concierge services and enjoy the vibrant shopping district right at their doorstep.
  • Other amenities: Alongside its luxurious offerings, the hotel boasts a serene spa with treatment rooms, a well-equipped fitness centre, and complimentary buffet breakfast. Guests can also take advantage of the air-conditioned rooms featuring minibars and daily housekeeping, ensuring a comfortable and straightforward stay. With additional services like self-parking and covered valet parking, every aspect of the visit is catered for, making it a top choice for discerning travellers.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 1.5 km, Calle 50 - 0 km, Via Espana - 1 km

Top Panama City Hotel Reviews

Decapolis Hotel Panama City

Decapolis Hotel Panama City

8/10 Good
"Decapolis hotel is in an excellent location, the breakfast buffet, the Bistro restaurant restaurant and gym are all nice. The rooms are clean and the bedding comfortable staff were friendly and helpful. However, the carpets especially on floor 19 need replacing or a deep clean. Floor 19 is also pretty loud I'm not sure what the cause is but I suspect it's the air-conditioning."
Alessandro Kamara 3-night trip
Posted 17 hours ago
Decapolis Hotel Panama City
Marriott Panama Hotel

Marriott Panama Hotel

10/10 Excellent
"Everything was good"
Andrew 5-night trip
Posted 1 day ago
Marriott Panama Hotel
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"The hotel is beautiful with really nice and spacious rooms. The pool area is unbelievable. Plus, a great location."
Geneva Smith 5-night trip
Posted 2 days ago
JW Marriott Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

8/10 Good
"Thanks"
natalia 3-night trip
Posted 2 days ago
Las Americas Golden Tower Panama
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

10/10 Excellent
"Excelente ubicación y precio"
Geiner 4-night trip
Posted 2 days ago
Hospedium Princess Hotel Panama
Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"Great location and very clean"
Reubin 6-night trip
Posted 3 days ago
Renaissance Panama City Hotel

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and Hyatt Regency Panama City are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Multicentro Panama.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina Station and Santo Tomás Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.

Explore a world of travel with Expedia