Florida Keys Hotel Guide - Luxury Hotels in Florida Keys, United States of America

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Luxury Hotels

This weekend
Next weekend

Our top choices for Florida Keys luxury hotels

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.4 out of 10, Very good, (171 reviews)
"Love their mattress. Happy stay. Everything is convenient. Will come back."
United States
Kexin
The price is €812
includes taxes & fees
26 Mar - 27 Mar
Villas At Hawks Cay Resort

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (71 reviews)
"Beautiful accommodations and location, very clean, many activities available at resort"
United States
Janet
The price is €925
includes taxes & fees
10 Mar - 11 Mar
The Islands of Islamorada

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1,004 reviews)
"The staff and management were super friendly and accommodating!"
United States
burton
The price is €633
includes taxes & fees
6 Apr - 7 Apr
Ocean Key Resort - A Noble House Resort

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,053 reviews)
"4th time staying, great staff, location "
United States
Jeffrey
Pier House Resort & Spa

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,101 reviews)
"great resort "
United States
Niki
The price is €588
includes taxes & fees
8 Mar - 9 Mar
Isla Bella Beach Resort & Spa

Santa Maria Suites

Santa Maria Suites
4.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,001 reviews)
"Great place to stay! Hope to come back!"
United States
Scott G.
The price is €813
includes taxes & fees
11 Mar - 12 Mar
Santa Maria Suites

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,300 reviews)
"Great staff and beautiful property "
United States
Julie
The price is €450
includes taxes & fees
12 Mar - 13 Mar
Cheeca Lodge & Spa

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (1,008 reviews)
"Hotel was very nice in all respects, but its location on the beach was the best."
United States
Stephen
The price is €542
includes taxes & fees
5 Apr - 6 Apr
The Reach Key West, Curio Collection by Hilton

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,067 reviews)
"Awsome resort. Great food and staff"
United States
Doug
The price is €542
includes taxes & fees
5 Apr - 6 Apr
Opal Key Resort & Marina, Key West

Southernmost House

Southernmost House
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,005 reviews)
"Excellent location, friendly staff, great amenities. Very happy we stayed there!"
United States
Gregory
The price is €632
includes taxes & fees
11 Mar - 12 Mar
Southernmost House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Florida Keysand its attractions for luxury travelers

The Florida Keys offer an exquisite playground for luxury travellers seeking both relaxation and adventure. Begin your journey in Key West, where you can explore the vibrant streets lined with historical architecture and indulge in exquisite dining at renowned establishments like Latitudes, known for its stunning sunset views and fresh seafood. Next, venture to the tranquil surroundings of Little Palm Island, a private resort accessible only by boat or seaplane, where you can unwind in a thatched-roof bungalow with unparalleled ocean views and a full-service spa. For those interested in marine life, a day trip to the Dry Tortugas National Park is a must; here, you can snorkel in crystal-clear waters, discovering vibrant coral reefs and diverse wildlife. The Keys also boast some of the finest fishing opportunities, with charter services available to take you out for a day on the water, targeting species like tarpon and bonefish. Finally, enjoy the laid-back elegance of Islamorada, where luxury resorts such as Cheeca Lodge offer lavish accommodations alongside activities like paddleboarding and sunset cruises. Staying in these luxurious settings ensures that every detail of your experience is catered to, allowing you to focus on making unforgettable memories.

Top Florida Keys Hotel Reviews