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Key West Hotel Guide - Florida Keys National Marine Sanctuary hotels in Key West, United States of America.

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Check prices for these dates

This weekend
31 Jul - 2 Aug
Next weekend
7 Aug - 9 Aug

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Our top choices for Florida Keys National Marine Sanctuary hotels

Queen Deluxe ADA

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,015 reviews)
"Staff was great,very helpful with suggestions different places to eat and site see.I would stay there again."
United States
Jonathan
The price is €202
includes taxes & fees
3 Aug - 4 Aug
Almond Tree Inn Hotel - Adults Only
Queen with Pool View

2. Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"Always a great stay!!"
United States
Robin
The price is €175
includes taxes & fees
4 Aug - 5 Aug
Simonton Court Historic Inn & Cottages
Exterior detail

3. The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"It was a great stay."
United States
Salvatore
The price is €196
includes taxes & fees
11 Aug - 12 Aug
The Gardens Hotel
Outdoor pool, open 8:00 AM to 7:00 PM, pool umbrellas, pool loungers

4. Tranquility Guest House

Tranquility Guest House
2.0 star property
Bahama Village, 0.5 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (9 reviews)
"It was a great property, very clean room and excellent price. Staff was great."
United States
Hector
The price is €158
includes taxes & fees
30 Aug - 31 Aug
Tranquility Guest House
Deluxe Suite, 1 King Bed, Private Pool | View from room

5. H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (629 reviews)
"Our favorite hotel there is! Amazing rooms and an even better staff. Best turn down service we have ever experienced with yummy muffins and dove bars, housekeeping is amazing! Roof top pool is first class and the bar tender Angie makes you feel at home!"
United States
James
The price is €342
includes taxes & fees
16 Aug - 17 Aug
H2O Suites - Adults Only
Property grounds

6. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,010 reviews)
"Wonderful place and staff!"
United States
William
The price is €201
includes taxes & fees
4 Aug - 5 Aug
Orchid Key Inn - Adults Only
Exterior

7. The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,001 reviews)
"Great location and beautiful property. I appreciate the parking which comes at a premium in Key West and the two swimming pools. Just enough off the beaten path to feel comfortable."
United States
Darrell
The price is €269
includes taxes & fees
16 Aug - 17 Aug
The Marquesa Hotel
Cigar House King Suite w/ Poolside porch | Balcony view

8. Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (999 reviews)
"Love this place!"
United States
Sean
The price is €167
includes taxes & fees
4 Aug - 5 Aug
Island City House Hotel
Exterior

9. Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (468 reviews)
"Gorgeous property with beautiful grounds!"
United States
Kevin
The price is €125
includes taxes & fees
3 Aug - 4 Aug
Douglas House - Adults Only
Courtyard

10. The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,001 reviews)
"Great location and fast internet"
United States
Travis
The price is €181
includes taxes & fees
31 Aug - 1 Sept
The Grand Guesthouse
Audubon Room - Adult Exclusive | Terrace/patio

11. The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (310 reviews)
"Beautiful property, the staff were so friendly! Loved the complimentary breakfast and happy hour. We can’t wait to come back."
United States
Kayla
The price is €218
includes taxes & fees
2 Aug - 3 Aug
The Mermaid & Alligator
2 outdoor pools, pool loungers

12. Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,014 reviews)
"Great location. Friendly staff and clean property"
United States
Veronica
The price is €311
includes taxes & fees
30 Aug - 31 Aug
Santa Maria Suites
Outdoor pool

13. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
3.5 star property
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,044 reviews)
"Nice staff and close to everything. I would stay there again"
United States
Alex
The price is €136
includes taxes & fees
18 Aug - 19 Aug
Silver Palms Inn & Historic Homes
Exterior

14. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,001 reviews)
"Great place, great location!"
United States
Mark
The price is €246
includes taxes & fees
26 Aug - 27 Aug
Southernmost House - Adult Exclusive
Exterior

15. Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (552 reviews)
"Perfect stay, we will be back!"
United States
Jake
The price is €175
includes taxes & fees
17 Aug - 18 Aug
Coco Plum Inn
3 outdoor pools, a heated pool, pool loungers

16. Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,000 reviews)
"Love the overall vibe. Private porch was nice. Pool was relaxing. Location was convenient for our needs."
United States
Jenina
The price is €184
includes taxes & fees
2 Aug - 3 Aug
Ambrosia Key West
Outdoor pool, open 8:00 AM to 10:00 PM, pool loungers

17. Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (489 reviews)
"Beautiful, boutique little gem with a wonderful staff!"
United States
Karri
The price is €242
includes taxes & fees
13 Aug - 14 Aug
Ella's Cottages - Key West Historic Inns
Terrace/patio

18. Marrero's Guest Mansion

Marrero's Guest Mansion
3.5 star property
Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (338 reviews)
"Just the right amount of perfect!"
United States
Dane
The price is €243
includes taxes & fees
11 Aug - 12 Aug
Marrero's Guest Mansion
Lobby

19. Authors of Key West Guest House

Authors of Key West Guest House
3.0 star property
The Meadows, 1.8 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,028 reviews)
"Wonderful place, great time!"
United States
Kasi
The price is €105
includes taxes & fees
18 Aug - 19 Aug
Authors of Key West Guest House
City view

20. Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place. Just wish they had a dock for fishing."
United States
Marcia
The price is €168
includes taxes & fees
9 Aug - 10 Aug
Paradise Inn Key West - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Queen Deluxe ADA
Almond Tree Inn Hotel - Adults Only
3.5 star property
10.0
Exceptional
1,015 reviews
View
Queen with Pool View
Simonton Court Historic Inn & Cottages
2.5 star property
9.8
Exceptional
1,000 reviews
View
Exterior detail
The Gardens Hotel
4.0 star property
9.8
Exceptional
1,000 reviews
View
Outdoor pool, open 8:00 AM to 7:00 PM, pool umbrellas, pool loungers
Tranquility Guest House
2.0 star property
9.8
Exceptional
9 reviews
View
Deluxe Suite, 1 King Bed, Private Pool | View from room
H2O Suites - Adults Only
3.5 star property
9.8
Exceptional
629 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

10/10 Excellent
"Everting super good"
Dayri 2-night trip
Posted 12 hours ago
The Reach Key West, Curio Collection by Hilton

Other attractions near Florida Keys National Marine Sanctuary

A yellow exhibit labeled 'NOAA's AQUARIUS UNDERSEA LAB' with a circular window and a door.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
See properties

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1522 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Caribbean House is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and private balconies. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1522 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Key West Historic Seaport are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Coffee Butler Amphitheater and Key West Film Society if you're interested in local theatre.