Key West Hotel Guide - Florida Keys National Marine Sanctuary hotels in Key West, United States of America.

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Check prices for these dates

Tonight
8 Nov - 9 Nov
Tomorrow
9 Nov - 10 Nov
Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

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Our top choices for Florida Keys National Marine Sanctuary hotels

A breakfast table with various food items and drinks, a pool in the background, and a tiled wall.

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,006 reviews)
"We really enjoyed our stay! The staff were amazing and the room was perfect!"
United States
Teresa
The price is €293
includes taxes & fees
30 Nov - 1 Dec
Almond Tree Inn Hotel - Adults Only
A tropical outdoor area with palm trees, hanging plants, and string lights.

2. Douglas House - Adults Only

Douglas House - Adults Only
3.5 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (585 reviews)
"Loved our stay! I would definitely stay there again."
United States
Maricela
The price is €252
includes taxes & fees
17 Nov - 18 Nov
Douglas House - Adults Only
A covered entrance with a brick pathway leading to a gated area, surrounded by lush greenery and plants.

3. Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (279 reviews)
"Great location and very hospitable hotel owners"
United States
Margaret
The price is €272
includes taxes & fees
18 Nov - 19 Nov
Key West Villas
An outdoor seating area with a modern fire feature, surrounded by lush greenery and palm trees.

4. H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (674 reviews)
"Amazing stay! Loved the private pool!"
United States
Kimberly
The price is €423
includes taxes & fees
30 Nov - 1 Dec
H2O Suites - Adults Only
A pool area with lounge chairs and a table, surrounded by palm trees.

5. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,006 reviews)
"Fantastic property. Love staying here 💗"
United States
Jessica
The price is €282
includes taxes & fees
15 Nov - 16 Nov
Orchid Key Inn - Adults Only
A modern interior with a staircase, a sofa set, a wooden table, and a television.

6. Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"Staff was great rooms are older but quite charming. Would definitely stay again."
United States
William
The price is €302
includes taxes & fees
9 Nov - 10 Nov
Simonton Court Historic Inn & Cottages
A two-story house with a covered porch, a brick pathway, and a large tree.

7. The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,002 reviews)
"This is my favorite hotel in the world, and Key West"
United States
Josh
The price is €462
includes taxes & fees
29 Nov - 30 Nov
The Marquesa Hotel
A porch with a white railing, a bench, and a flag.

8. The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (198 reviews)
"We really enjoyed getting to know the staff. The breakfast was excellent and everything was in walking distance."
United States
Jennifer
The price is €337
includes taxes & fees
24 Nov - 25 Nov
The Conch House Heritage Inn
A wooden deck with a hammock, pool, and lounge chairs overlooking a tropical garden.

9. Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place with lots of character and perfect location."
United States
Elise
The price is €203
includes taxes & fees
1 Dec - 2 Dec
Island City House Hotel
A wooden deck with white railings, surrounded by lush greenery and a staircase leading to a building.

10. Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,138 reviews)
"Great stay!"
United States
Dennis
The price is €199
includes taxes & fees
18 Nov - 19 Nov
Duval House
A room with a bed, a ceiling fan, and a window with blinds.

11. The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (331 reviews)
"such a lovely location. nice and quiet for a restful stay. staff was attentive to all our needs. would definitely return"
United States
christine
The price is €319
includes taxes & fees
29 Nov - 30 Nov
The Mermaid & Alligator
A pool area with lounge chairs and palm trees.

12. Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,003 reviews)
"Great place for families"
United States
Anthony
The price is €443
includes taxes & fees
2 Dec - 3 Dec
Santa Maria Suites
A large, ornate hotel with a pool, palm trees, and a view of the ocean.

13. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,003 reviews)
"Such a wonderful peaceful place to stay! Great food close by and Duval Street"
United States
Edward Lance
The price is €325
includes taxes & fees
16 Nov - 17 Nov
Southernmost House - Adult Exclusive
A poolside area with lounge chairs and a clear blue pool surrounded by lush tropical vegetation.

14. Westwinds Inn

Westwinds Inn
3.5 star property
Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,006 reviews)
"Breakfast was great . Pools were great and easy walk or bike ride to Duval street"
United States
Shari
The price is €218
includes taxes & fees
29 Nov - 30 Nov
Westwinds Inn
A green house with a white porch, a flag, and a sign advertising a property for sale.

15. L'Habitation Guest House - Adults Only

L'Habitation Guest House - Adults Only
2.5 star property
Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,003 reviews)
"A very cute, cozy and comfortable place to stay especially for old Key West charm. Will definitely stay here again."
United States
Callie
The price is €172
includes taxes & fees
1 Dec - 2 Dec
L'Habitation Guest House - Adults Only
A rectangular pool with a white deck, surrounded by lush greenery and a gazebo.

16. Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,002 reviews)
"Great location beautiful property we enjoyed our stay !"
United States
daniela
The price is €248
includes taxes & fees
30 Nov - 1 Dec
Ambrosia Key West
A swimming pool with lounge chairs, a covered deck, and a view of lush greenery.

17. Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (578 reviews)
"Location was perfect"
United States
August
The price is €268
includes taxes & fees
16 Nov - 17 Nov
Coco Plum Inn
A poolside area with lounge chairs, umbrellas, and a pergola.

18. Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (520 reviews)
"Clean room, comfortable bed, friendly staff, good amenities!"
United States
Lisa and David
The price is €268
includes taxes & fees
30 Nov - 1 Dec
Ella's Cottages - Key West Historic Inns
A swimming pool with water splashing, surrounded by palm trees and a building in the background.

19. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
3.5 star property
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,036 reviews)
"Great location Beautiful property very clean and quiet. Great omelet station w breakfast."
United States
Carleen
The price is €214
includes taxes & fees
1 Dec - 2 Dec
Silver Palms Inn & Historic Homes
A room with a door featuring horizontal blinds, a visible outdoor view through the window, and a patterned carpet.

20. Alexander Palms Court

Alexander Palms Court
2.5 star property
Casa Marina, 1.4 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,006 reviews)
"We love staying at Alexander’s!!!"
United States
Brenda
The price is €200
includes taxes & fees
9 Dec - 10 Dec
Alexander Palms Court
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A breakfast table with various food items and drinks, a pool in the background, and a tiled wall.
Almond Tree Inn Hotel - Adults Only
3.5 star property
10.0
Exceptional
1,006 reviews
View
A tropical outdoor area with palm trees, hanging plants, and string lights.
Douglas House - Adults Only
3.5 star property
9.8
Exceptional
585 reviews
View
A covered entrance with a brick pathway leading to a gated area, surrounded by lush greenery and plants.
Key West Villas
3.5 star property
9.8
Exceptional
279 reviews
View
An outdoor seating area with a modern fire feature, surrounded by lush greenery and palm trees.
H2O Suites - Adults Only
3.5 star property
9.8
Exceptional
674 reviews
View
A pool area with lounge chairs and a table, surrounded by palm trees.
Orchid Key Inn - Adults Only
3.5 star property
9.8
Exceptional
1,006 reviews
View

Other attractions near Florida Keys National Marine Sanctuary

An aquarium exhibit with fish tanks and informational displays.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
See properties

Top Florida Keys National Marine Sanctuary Hotel Reviews

A pool area with lounge chairs and a table, surrounded by palm trees.
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Old Town Key West

10/10 Excellent

FABULOUS! Friendly and efficient mgmt & staff. Beautiful renovations and decorating. Property and amenities well-maintained and working wonderfully. Superb location. Great bar/lounge on property. Will be back. Thank you.
Ireland
Deborah
Reviewed December 11, 2020
Orchid Key Inn - Adults Only

Frequently Asked Questions

What's the area like around Florida Keys National Marine Sanctuary?

Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1487 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Florida Keys National Marine Sanctuary?

Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveller data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.

How many hotels will I find near Florida Keys National Marine Sanctuary?

Expedia has 1487 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.

If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the hotel’s cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.

What can I see and do near Florida Keys National Marine Sanctuary?

Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Fort East Martello Museum and Gallery are some of the notable landmarks to see in the area. You can watch performances at Red Barn Theater, Coffee Butler Amphitheater and Key West Film Society if you're interested in local theatre.