A densely packed urban area with numerous buildings and a prominent tower on a hill.

Guayaquil Hotel Guide. Hotels in Puerto Santa Ana, Guayaquil, Ecuador

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Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Puerto Santa Ana hotels

A modern bar area with a bar counter, seating, and a large window.

1. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (1,001 reviews)
"Excelente hotel"
United States
Juan
The price is €106
8 Nov - 9 Nov
Wyndham Guayaquil Puerto Santa Ana
A rooftop pool with a view of the city skyline.

2. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (111 reviews)
"So clean and very nice people. I really recommend this facility, nice environment. My next trip lm booking in this apartment"
United States
Pedro
Luxury Suites Riverfront GYE
A rooftop terrace with outdoor seating, a pool, and a city view at sunset.

3. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (65 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is €80
1 Nov - 2 Nov
River View suites Puerto Santa Ana gye
A grand room with ornate chandeliers, a large sofa, a round armchair, and a fireplace.

4. Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (148 reviews)
"Great place historical. Good service n breakfast. Great location"
United States
Mary Grant
The price is €59
14 Oct - 15 Oct
Mansión del Río
An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

5. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very good, (418 reviews)
"👍"
United States
Washington
The price is €57
19 Oct - 20 Oct
Hotel Ramada
An outdoor cafe with tables and chairs, surrounded by trees and buildings.

6. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
7.6 out of 10, Good, (10 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is €38
13 Oct - 14 Oct
Fortune Hotel
A modern hotel lobby with a reception desk, seating area, and a large decorative plant.

7. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,002 reviews)
"Great locations and wonderful staff.!!"
Canada
Carlos
The price is €76
30 Oct - 31 Oct
Courtyard by Marriott Guayaquil
A breakfast table with various foods and a view of a park through a window.

8. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Clean hospitality excellent place to stay. Would come again ."
United States
silvia
The price is €63
1 Nov - 2 Nov
Unipark by Oro Verde Hotels
A bathroom with a bathtub, a stone wall, a window with a view, and a table with chairs.

9. Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (5 reviews)
"Outstanding staff - great property"
United States
septimiu
Hotel Río Guayas by Art Hotels Ecuador
A cocktail on a marble table with a pool in the background.

10. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very good, (166 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is €42
1 Nov - 2 Nov
Hotel Patrimonial by Greenfield
A modern lobby with large windows, a staircase, and comfortable seating areas.

11. Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (130 reviews)
"Good staff...great location"
United States
ALBERTO
The price is €87
18 Oct - 19 Oct
Doubletree By Hilton Guayaquil
An aerial view of a hotel with a swimming pool surrounded by lush greenery and a decorative garden.

12. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Great location, great breakfast buffet, adjacent to Iguana park, not far from airport."
Canada
Victor
The price is €77
18 Oct - 19 Oct
Grand Hotel Guayaquil, Centro Histórico.
A buffet setup with various food items, a modern chandelier, and a patterned floor.

13. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (348 reviews)
"Nice restaurant. Great location. Room was a good place to rest."
United States
Hector
The price is €63
23 Oct - 24 Oct
Ibis Styles El Malecon Guayaquil
A room with a hammock, striped sofas, a stone floor, and a ceiling fan.

14. NCG SUITE ATARAZANA

NCG SUITE ATARAZANA
2.0 star property
La Atarazana, 0.8 km from Puerto Santa Ana
The price is €36
13 Oct - 14 Oct
NCG SUITE ATARAZANA
A buffet setup with pastries and various food items in jars.

15. Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (690 reviews)
"Breakfast lots of variety, service is good, free shuttle from airport"
Canada
Victoria
The price is €97
30 Oct - 31 Oct
Sheraton Guayaquil Hotel
A bedroom with a large bed, a desk, a chair, and a mural on the wall.

16. HOTEL PERLA CENTRAL MALECON

HOTEL PERLA CENTRAL MALECON
2.5 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
7.2 out of 10, Good, (30 reviews)
"Great location and friendly staff. We had a great stay."
Australia
Ashleigh
The price is €28
14 Oct - 15 Oct
HOTEL PERLA CENTRAL MALECON
A modern bar area with a bar counter, stools, and a seating area with a table and chairs.

17. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is €84
30 Oct - 31 Oct
Wyndham Garden Guayaquil
A person in a swimsuit and red hat sitting on a green inflatable ring in a pool.

18. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,004 reviews)
"Easy check in and staff very friendly"
United States
Michael
The price is €95
18 Oct - 19 Oct
Oro Verde Guayaquil
A neatly made bed with a heart-shaped arrangement of red roses, a champagne bucket, and two wine glasses on a tray.

19. San Francisco Apart Hotel

San Francisco Apart Hotel
3.0 star property
La Atarazana, 1.4 km from Puerto Santa Ana
6.6 out of 10, (26 reviews)
"Nice place, nice amenities, nice staff, we'll back! "
United States
Giovanny
The price is €32
18 Oct - 19 Oct
San Francisco Apart Hotel
A hotel room with a bed, a nightstand, a desk, a chair, and a window with curtains.

20. Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 1.8 km from Puerto Santa Ana
8.4 out of 10, Very good, (124 reviews)
"Great location, kind staff, would recommend"
United States
Melida
The price is €25
16 Oct - 17 Oct
Hotel Las Peñas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

A colorful outdoor installation with large letters spelling out a word.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Artisan Market while you're in town.

A lizard on a metal fence.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A cityscape with a prominent skyscraper, a river, and a bridge.

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

A densely packed hillside cityscape with colorful buildings and a prominent tower against a sunset sky.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Alban Borja Commercial Center.

Top Puerto Santa Ana Hotel Reviews

Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil

10/10 Excellent
"Excelente"
diana 1-night trip
Posted 9 hours ago
Courtyard by Marriott Guayaquil

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 88 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Santa Ana Hill are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Numa Pompilio Llona Street and El Carmen Hill are a couple of additional sights to visit in Guayaquil.

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