A densely packed urban area with numerous buildings and a prominent tower on a hill.

Guayaquil Hotel Guide. Hotels in Puerto Santa Ana, Guayaquil, Ecuador

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Check prices for these dates

This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

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Our top choices for Puerto Santa Ana hotels

Bar (on property)

1. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (1,006 reviews)
"Great hotel to stay in! Staff was super friendly!"
United States
Isabel
The price is €111
13 Sept - 14 Sept
Wyndham Guayaquil Puerto Santa Ana
Outdoor spa tub

2. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (109 reviews)
"So clean and very nice people. I really recommend this facility, nice environment. My next trip lm booking in this apartment"
United States
Pedro
The price is €74
7 Sept - 8 Sept
Luxury Suites Riverfront GYE
Rooftop terrace

3. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (62 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is €93
7 Sept - 8 Sept
River View suites Puerto Santa Ana gye
Lobby lounge

4. Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (146 reviews)
"Great place historical. Good service n breakfast. Great location"
United States
Mary Grant
The price is €57
5 Oct - 6 Oct
Mansión del Río
Deluxe Room, 1 Double Bed with Sofa bed

5. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (336 reviews)
"Great location."
United States
George S
The price is €58
5 Sept - 6 Sept
Ibis Styles El Malecon Guayaquil
Pool

6. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
"Good service but just inconsistent Internet/wi-fi. Beautiful hotel."
United States
Maria
The price is €65
3 Oct - 4 Oct
Grand Hotel Guayaquil, Centro Histórico.
Food and drink

7. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very good, (163 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is €39
5 Sept - 6 Sept
Hotel Patrimonial by Greenfield
Breakfast meal

8. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,011 reviews)
"Excellent hotel"
United States
Monica
The price is €70
27 Sept - 28 Sept
Unipark by Oro Verde Hotels
Lobby

9. Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (124 reviews)
"Good staff...great location"
United States
ALBERTO
The price is €81
3 Oct - 4 Oct
Doubletree By Hilton Guayaquil
Ecotours

10. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
7.6 out of 10, Good, (9 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is €43
5 Oct - 6 Oct
Fortune Hotel
Lobby

11. Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (950 reviews)
"There’s a restaurant downstairs. Try the Encocado de camarón. Best food ever!"
United States
Marlaynna
The price is €63
19 Sept - 20 Sept
Hotel Palace Guayaquil
Lobby

12. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,000 reviews)
"Good staff, excelent food. I will defenetly will come back"
United States
Gloria E
The price is €77
19 Sept - 20 Sept
Courtyard by Marriott Guayaquil
Indoor pool

13. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very good, (410 reviews)
"Love the area where the hotel is located. Excellent breakfast. The pool area is beautiful where you can seat and relax "
United States
Sixto
The price is €55
24 Sept - 25 Sept
Hotel Ramada
Gym

14. Hotel Cityzen Guayaquil

Hotel Cityzen Guayaquil
3.0 star property
Roca, 1.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (43 reviews)
"Great central location in Centro (Downtown) Guayaquil. The staff were very helpful and always there when I needed them."
United States
Tahmidul
The price is €44
10 Sept - 11 Sept
Hotel Cityzen Guayaquil
Terrace/patio

15. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 2.7 km from Puerto Santa Ana
8.4 out of 10, Very good, (255 reviews)
"👍"
United States
Marcos
The price is €62
1 Oct - 2 Oct
Hotel Marcelius
Bar (on property)

16. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is €77
13 Sept - 14 Sept
Wyndham Garden Guayaquil
Comfort Double Room

17. Hotel GH Alexander

Hotel GH Alexander
3.5 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.6 out of 10, Excellent, (45 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
The price is €27
5 Sept - 6 Sept
Hotel GH Alexander
Children’s activities

18. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,001 reviews)
"Great breakfast, friendly and helpful staff."
United States
VICENTE
The price is €90
19 Sept - 20 Sept
Oro Verde Guayaquil
Room

19. Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 1.8 km from Puerto Santa Ana
8.4 out of 10, Very good, (122 reviews)
"Great location, kind staff, would recommend"
United States
Melida
The price is €27
5 Oct - 6 Oct
Hotel Las Peñas
Junior Suite, 1 Double Bed, Kitchenette

20. San Francisco Apart Hotel

San Francisco Apart Hotel
3.0 star property
La Atarazana, 1.4 km from Puerto Santa Ana
6.4 out of 10, (25 reviews)
"Nice place, nice amenities, nice staff, we'll back! "
United States
Giovanny
The price is €31
5 Sept - 6 Sept
San Francisco Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

A golden statue of two figures forming a heart shape on a paved area with a modern building in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

Top Puerto Santa Ana Hotel Reviews

Hilton Colon Guayaquil

Hilton Colon Guayaquil

10/10 Excellent
"This place is extremely nice and clean."
luis 1-night trip
Posted 9 hours ago
Hilton Colon Guayaquil

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 90 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Santa Ana Hill are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Numa Pompilio Llona Street and El Carmen Hill are a couple of additional sights to visit in Guayaquil.

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