A densely packed urban area with numerous buildings and a prominent tower on a hill.

Guayaquil Hotel Guide. Hotels in Puerto Santa Ana, Guayaquil, Ecuador

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Check prices for these dates

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

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Our top choices for Puerto Santa Ana hotels

A modern living room with a large window, a flat-screen TV, a sofa, and a coffee table.

1. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (1,010 reviews)
"Love staying at this hotel!"
United States
Isabel
The price is €109
15 Nov - 16 Nov
Wyndham Guayaquil Puerto Santa Ana
A laptop on a glass table with a plate of food and a chair in a room with a view of the sea.

2. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (67 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is €80
16 Nov - 17 Nov
River View suites Puerto Santa Ana gye
A rooftop pool with a view of the city skyline.

3. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (112 reviews)
"So clean and very nice people. I really recommend this facility, nice environment. My next trip lm booking in this apartment"
United States
Pedro
The price is €78
16 Nov - 17 Nov
Luxury Suites Riverfront GYE
A grand room with ornate chandeliers, a large mirror, and a staircase leading to another level.

4. Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (152 reviews)
"The facility is very unique. Staff are very friendly. We have an early flight so did not get a chance to have breakfast."
United States
Shuyi
The price is €53
8 Nov - 9 Nov
Mansión del Río
A modern building with the Fortune Hotel sign, featuring a flat facade, large windows, and a gated entrance.

5. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
8.0 out of 10, Very good, (12 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is €45
20 Nov - 21 Nov
Fortune Hotel
An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

6. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very good, (422 reviews)
"Excelente atención, good service, sauna and pull in great condition, food very good"
United States
Pedro
The price is €57
8 Nov - 9 Nov
Hotel Ramada
A rooftop pool with a curved edge, lounge chairs, and potted plants.

7. Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (6 reviews)
"Outstanding staff - great property"
United States
septimiu
The price is €295
9 Nov - 10 Nov
Hotel Río Guayas by Art Hotels Ecuador
A hot tub surrounded by palm trees and a brick wall, with a metal railing in the foreground.

8. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,001 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is €72
13 Nov - 14 Nov
Wyndham Garden Guayaquil
A spacious living area with a sectional sofa, a round coffee table, and a large vase. There is a view of trees through the windows.

9. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,003 reviews)
"The best hotel ever"
United States
Monica
The price is €66
20 Nov - 21 Nov
Unipark by Oro Verde Hotels
A modern hotel lobby with a reception desk, seating area, and a large decorative plant.

10. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,003 reviews)
"Todo excelente!"
United States
Richard
The price is €76
20 Nov - 21 Nov
Courtyard by Marriott Guayaquil
A swimming pool with a tiled deck, surrounded by buildings with large windows and a balcony.

11. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very good, (169 reviews)
"Was ok"
United States
Juan
The price is €37
14 Nov - 15 Nov
Hotel Patrimonial by Greenfield
An indoor pool with a waterfall, surrounded by lush tropical plants.

12. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Great location, great breakfast buffet, adjacent to Iguana park, not far from airport."
Canada
Victor
The price is €84
8 Nov - 9 Nov
Grand Hotel Guayaquil, Centro Histórico.
A hotel lobby with a modern design, featuring a reception desk, seating area, and decorative columns.

13. Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (968 reviews)
"We have stayed at this hotel several times and it is consistently a good experience. Comfortable bed, good air conditioning, restaurant on site, farmacia nearby. The breakfast buffet is especially good."
United States
Bethany
The price is €58
20 Nov - 21 Nov
Hotel Palace Guayaquil
A room with a hammock, striped sofas, a stone floor, and a ceiling fan.

14. NCG SUITE ATARAZANA

NCG SUITE ATARAZANA
2.0 star property
La Atarazana, 0.8 km from Puerto Santa Ana
The price is €36
8 Nov - 9 Nov
NCG SUITE ATARAZANA
An outdoor seating area with tables and chairs, potted plants, and a view of trees through large windows.

15. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (360 reviews)
"Nice restaurant. Great location. Room was a good place to rest."
United States
Hector
The price is €60
27 Nov - 28 Nov
Ibis Styles El Malecon Guayaquil
A modern living room with a sectional sofa, a yellow armchair, and a wooden coffee table.

16. Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (761 reviews)
"Very helpful and accommodating airport shuttle service."
United States
Jerry
The price is €77
8 Nov - 9 Nov
Radisson Hotel Guayaquil
A rooftop pool area with lounge chairs, a bar, and a view of the city skyline.

17. Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (132 reviews)
"Good staff...great location"
United States
ALBERTO
The price is €87
20 Nov - 21 Nov
Doubletree By Hilton Guayaquil
A neatly made bed with a heart-shaped arrangement of red roses, a champagne bucket, and two wine glasses on a tray.

18. San Francisco Apart Hotel

San Francisco Apart Hotel
3.0 star property
La Atarazana, 1.4 km from Puerto Santa Ana
6.6 out of 10, (26 reviews)
"Nice place, nice amenities, nice staff, we'll back! "
United States
Giovanny
The price is €32
20 Nov - 21 Nov
San Francisco Apart Hotel
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

19. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,003 reviews)
"Very friendly staff, excellent breakfast, maintained and modern rooms. Was a great stay."
United States
ricardo
The price is €91
20 Nov - 21 Nov
Oro Verde Guayaquil
A reception desk with a marble top and a modern light fixture above it.

20. TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,000 reviews)
"Convenient near airport."
United States
MIGUEL A.
The price is €91
15 Nov - 16 Nov
TRYP by Wyndham Guayaquil Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Puerto Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern living room with a large window, a flat-screen TV, a sofa, and a coffee table.
Wyndham Guayaquil Puerto Santa Ana
4.5 star property
9.4
Exceptional
1,010 reviews
View
A rooftop pool with a view of the city skyline.
Luxury Suites Riverfront GYE
3.5 star property
9.4
Exceptional
112 reviews
View
A laptop on a glass table with a plate of food and a chair in a room with a view of the sea.
River View suites Puerto Santa Ana gye
3.0 star property
9.0
Wonderful
67 reviews
View
A rooftop pool with a curved edge, lounge chairs, and potted plants.
Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
10.0
Exceptional
6 reviews
View
A hotel with a modern facade, featuring a prominent vertical light installation.
Hotel Sada
3.0 star property
9.8
Exceptional
12 reviews
View

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

A colorful outdoor installation with large letters spelling out a word.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Artisan Market while you're in town.

A lizard on a metal fence.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A cityscape with a prominent skyscraper, a river, and a bridge.

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

Top Puerto Santa Ana Hotel Reviews

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

10/10 Excellent
"Sin duda, una excelente opción para quienes buscan comodidad, buena atención y una experiencia agradable en Guayaquil. ¡Recomiendo Unipark Hotel y volvería a hospedarme allí!"
Ab. Juan 1-night trip
Posted 9 hours ago
Unipark by Oro Verde Hotels

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 88 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Santa Ana Hill are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Numa Pompilio Llona Street and El Carmen Hill are a couple of additional sights to visit in Guayaquil.

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