What's it like in Puerto Santa Ana?

Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.

Where is the best hotel for a stay in Puerto Santa Ana?

Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE .

How many hotels should I expect to find in Puerto Santa Ana?

If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 89 Puerto Santa Ana hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?

Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.

What is there to do around this Guayaquil neighbourhood?

Emporium by The Point, Santa Ana Garden and Santa Ana Hill are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Numa Pompilio Llona Street and El Carmen Hill are a couple of additional sights to visit in Guayaquil.

Puerto Santa Ana hotels, Guayaquil, Ecuador: Guayaquil Hotel Guide

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Puerto Santa Ana hotels

A modern bar area with a bar counter, seating, and a large window.

1. Wyndham Guayaquil Puerto Santa Ana

Puerto Santa Ana

Isabel

25 Sept - 26 Sept

A rooftop terrace with outdoor seating, a pool, and a city view at sunset.

2. River View suites Puerto Santa Ana gye

Puerto Santa Ana

Aaliyah

23 Sept - 24 Sept

A grand room with ornate chandeliers, a large sofa, a round armchair, and a fireplace.

3. Mansión del Río

Las Peñas, 0.6 km from Puerto Santa Ana

Mary Grant

23 Sept - 24 Sept

A cocktail on a marble table with a pool in the background.

4. Hotel Patrimonial by Greenfield

Downtown Guayaquil, 1.4 km from Puerto Santa Ana

Julio

23 Sept - 24 Sept

A buffet setup with various food items, a modern chandelier, and a patterned floor.

5. Ibis Styles El Malecon Guayaquil

Downtown Guayaquil, 1.7 km from Puerto Santa Ana

Carmen

26 Sept - 27 Sept

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

6. Hotel Ramada

Downtown Guayaquil, 1.3 km from Puerto Santa Ana

Washington

24 Sept - 25 Sept

A modern lobby with large windows, a staircase, and comfortable seating areas.

7. Doubletree By Hilton Guayaquil

Downtown Guayaquil, 1.7 km from Puerto Santa Ana

ALBERTO

9 Oct - 10 Oct

A gym with various exercise equipment, including a stationary bike, an elliptical trainer, and a treadmill. There is a potted plant and a mirror on the wall.

8. Hotel Cityzen Guayaquil

Roca, 1.6 km from Puerto Santa Ana

Fred

23 Sept - 24 Sept

A hotel entrance with a sign reading "HOTEL Presidente."

9. Hotel Presidente Internacional

Roca, 1.6 km from Puerto Santa Ana

Victor

9 Oct - 10 Oct

A modern hotel lobby with a reception desk, seating area, and a large decorative plant.

10. Courtyard by Marriott Guayaquil

Kennedy, 2.5 km from Puerto Santa Ana

Carlos

25 Sept - 26 Sept

A hotel lobby with a modern design, featuring a reception desk, seating area, and decorative columns.

11. Hotel Palace Guayaquil

Rocafuerte, 1.9 km from Puerto Santa Ana

Marlaynna

27 Sept - 28 Sept

A hotel room with a bed, a nightstand, a desk, a chair, and a window with curtains.

12. Hotel Las Peñas

Rocafuerte, 1.8 km from Puerto Santa Ana

Melida

26 Sept - 27 Sept

An aerial view of a hotel with a swimming pool surrounded by lush greenery and a decorative garden.

13. Grand Hotel Guayaquil, Centro Histórico.

Rocafuerte, 2.2 km from Puerto Santa Ana

Edwin

27 Sept - 28 Sept

A breakfast table with various foods and a view of a park through a window.

14. Unipark by Oro Verde Hotels

Rocafuerte, 2 km from Puerto Santa Ana

Monica

11 Oct - 12 Oct

An outdoor cafe with tables and chairs, surrounded by trees and buildings.

15. Fortune Hotel

River City, 1 km from Puerto Santa Ana

MARIA

23 Sept - 24 Sept

A hotel with a modern facade, featuring a prominent vertical light installation.

16. Hotel Sada

Roca, 1.5 km from Puerto Santa Ana

Ligia

25 Sept - 26 Sept

An outdoor patio with wicker furniture, a stone wall, and a water feature.

17. Hotel Marcelius

Kennedy, 2.7 km from Puerto Santa Ana

Marcos

25 Sept - 26 Sept

A modern hotel room with a bed, bedside table, and a desk with a chair.

18. Hotel Varadero Internacional

Downtown Guayaquil, 1.7 km from Puerto Santa Ana

Daniel

28 Sept - 29 Sept

A couple in bed with a tray of breakfast including toast, fruit, and juice.

19. The Park Hotel

Rocafuerte, 2 km from Puerto Santa Ana

Isaiah

21 Oct - 22 Oct

A bedroom with a bed, pillows, a fan, and a painting on the wall.

20. Malecon Guesthouse

River City, 1 km from Puerto Santa Ana

JHANDRY JHAEL

23 Sept - 24 Sept

View all properties

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.

A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

See properties

A colorful outdoor installation with large letters spelling out a word.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Artisan Market while you're in town.

See properties

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

See properties

A densely packed hillside cityscape with colorful buildings and a prominent tower against a sunset sky.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or San Marino Mall.

See properties

A coastal cityscape at dusk with a prominent Ferris wheel, high-rise buildings, and a busy street.

Garzota

The restaurants and shopping are a few reasons travellers visit Garzota. Though there aren't many top sights in the neighbourhood, you can visit Mall del Sol Shopping Center and City Mall, a few notable attractions nearby.

See properties