A densely packed urban area with numerous buildings and a prominent tower on a hill.

Guayaquil Hotel Guide. Hotels in Puerto Santa Ana, Guayaquil, Ecuador

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Check prices for these dates

Next weekend
14 Aug - 16 Aug
In two weeks
21 Aug - 23 Aug

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Our top choices for Puerto Santa Ana hotels

2 bars/lounges, lobby lounge

1. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,008 reviews)
"Nice river view, clean room, nice staff and breakfast buffet great!!!"
United States
Nancy
The price is €107
23 Aug - 24 Aug
Wyndham Guayaquil Puerto Santa Ana
Outdoor spa tub

2. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (107 reviews)
"Lots of restaurants nearby"
Canada
kevin
The price is €75
12 Aug - 13 Aug
Luxury Suites Riverfront GYE
Rooftop terrace

3. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (60 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is €77
9 Aug - 10 Aug
River View suites Puerto Santa Ana gye
Lobby lounge

4. Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (143 reviews)
"Great place historical. Good service n breakfast. Great location"
United States
Mary Grant
The price is €57
9 Aug - 10 Aug
Mansión del Río
Lobby

5. Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (122 reviews)
"Good staff...great location"
United States
ALBERTO
The price is €82
15 Aug - 16 Aug
Doubletree By Hilton Guayaquil
Restaurant

6. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (324 reviews)
"Great location."
United States
George S
The price is €58
9 Aug - 10 Aug
Ibis Styles El Malecon Guayaquil
Free daily buffet breakfast

7. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,006 reviews)
"Great place to stay for any occasion!"
United States
Pedro
The price is €68
9 Aug - 10 Aug
Unipark by Oro Verde Hotels
Outdoor pool, open 8:00 AM to 9:00 PM, pool loungers

8. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,008 reviews)
"I enjoyed everything about this hotel."
United States
Maria Dorila
The price is €70
7 Sept - 8 Sept
Grand Hotel Guayaquil, Centro Histórico.
Lobby

9. Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (945 reviews)
"There’s a restaurant downstairs. Try the Encocado de camarón. Best food ever!"
United States
Marlaynna
The price is €58
9 Aug - 10 Aug
Hotel Palace Guayaquil
Food and drink

10. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very good, (158 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is €39
9 Aug - 10 Aug
Hotel Patrimonial by Greenfield
Lobby

11. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,009 reviews)
"Great locations and wonderful staff.!!"
Canada
Carlos
The price is €77
9 Aug - 10 Aug
Courtyard by Marriott Guayaquil
Indoor pool, open 8:00 AM to 10 PM, pool loungers

12. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very good, (408 reviews)
"Love the area where the hotel is located. Excellent breakfast. The pool area is beautiful where you can seat and relax "
United States
Sixto
The price is €55
29 Aug - 30 Aug
Hotel Ramada
Ecotours

13. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
8.4 out of 10, Very good, (8 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is €37
11 Aug - 12 Aug
Fortune Hotel
Terrace/patio

14. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 2.7 km from Puerto Santa Ana
8.4 out of 10, Very good, (250 reviews)
"👍"
United States
Marcos
The price is €63
9 Aug - 10 Aug
Hotel Marcelius
Gym

15. Hotel Cityzen Guayaquil

Hotel Cityzen Guayaquil
3.0 star property
Roca, 1.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (42 reviews)
"Great central location in Centro (Downtown) Guayaquil. The staff were very helpful and always there when I needed them."
United States
Tahmidul
The price is €44
16 Aug - 17 Aug
Hotel Cityzen Guayaquil
Suite, Jetted Tub

16. Hotel Varadero Internacional

Hotel Varadero Internacional
3.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
8.2 out of 10, Very good, (80 reviews)
"Overall a good place to stay and close to most destinations."
United States
Daniel
The price is €24
9 Aug - 10 Aug
Hotel Varadero Internacional
Children’s activities

17. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,009 reviews)
"Definitely the best and friendliest Hotel in Guayaquil!"
United States
Josef Walter
The price is €77
9 Aug - 10 Aug
Oro Verde Guayaquil
Lobby

18. Hotel GH Galeria

Hotel GH Galeria
3.5 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
8.4 out of 10, Very good, (411 reviews)
"So so experience."
United States
Daniel
The price is €57
29 Aug - 30 Aug
Hotel GH Galeria
Down duvets, desk, free WiFi, bed sheets

19. Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 1.8 km from Puerto Santa Ana
8.4 out of 10, Very good, (121 reviews)
"Great location, kind staff, would recommend"
United States
Melida
The price is €36
9 Aug - 10 Aug
Hotel Las Peñas
Property entrance

20. Hotel Presidente Internacional

Hotel Presidente Internacional
3.5 star property
Roca, 1.6 km from Puerto Santa Ana
6.6 out of 10, (35 reviews)
"Ok"
United States
Victor
The price is €38
4 Sept - 5 Sept
Hotel Presidente Internacional
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A golden statue of two figures forming a heart shape on a paved area with a modern building in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or Santa Ana Port.

Top Puerto Santa Ana Hotel Reviews

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

8/10 Good
"Everything was okay. I dropped something and learned under the bed was rather dusty, but the bathroom was spotless. I was charged 7.50 for the airport shuttle. Mind you, it’s a 3.00 taxi but I prefer a shuttle for safety sake. I asked for the shuttle to take me to the airport at 9 am the evening before, when I checked in, they immediately charged me. At 9am (after a really good breakfast buffet), I asked at the downstairs front desk about my airport shuttle. First they didn’t have it recorded. Then the man from the desk just went out and flagged down a random taxi to put me. I could’ve done that myself for half what they charged me! So much for my safety concerns. It was taxi with no AC, the windows didn’t function and the doors couldn’t be opened from inside. What I like to call a terror taxi."
Christina 1-night trip
Posted 2 hours ago
Unipark by Oro Verde Hotels

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 90 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.

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