A brick-paved street lined with historic buildings and a yellow fire hydrant.

St. Louis Hotel Guide - Historic Main Street hotels in St. Louis, United States of America.

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Check prices for these dates

Tonight
8 Aug - 9 Aug
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9 Aug - 10 Aug
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14 Aug - 16 Aug
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21 Aug - 23 Aug

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Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
1.8 km from Historic Main Street
United States
Jamie
€140
includes taxes & fees
27 Aug - 28 Aug
Drury Plaza Hotel St. Louis St. Charles

2. Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
1.5 km from Historic Main Street
United Kingdom
Nicola
€105
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn & Suites St. Charles Old Town Area

3. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
2.1 km from Historic Main Street
United States
Denise
€146
includes taxes & fees
16 Aug - 17 Aug
Embassy Suites by Hilton St. Louis St. Charles

4. Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.1 km from Historic Main Street
United States
Terri
€96
includes taxes & fees
6 Sept - 7 Sept
Tru by Hilton St. Charles St. Louis, MO

5. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3 km from Historic Main Street
United States
WAYNE
€127
includes taxes & fees
16 Aug - 17 Aug
Hollywood Casino & Hotel St. Louis

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
1.4 km from Historic Main Street
United States
Tracey
€164
includes taxes & fees
7 Sept - 8 Sept
Ameristar Casino Resort and Spa

7. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
1.5 km from Historic Main Street
United States
Michelle
€84
includes taxes & fees
6 Sept - 7 Sept
Comfort Suites St Charles - St Louis

8. Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
1.5 km from Historic Main Street
United States
Melisa
€93
includes taxes & fees
31 Aug - 1 Sept
Best Western Plus The Charles Hotel

9. Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
3.1 km from Historic Main Street
United States
Brandi
€92
includes taxes & fees
30 Aug - 31 Aug
Elimwood Hotel, a Ramada by Wyndham

10. Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
2.9 km from Historic Main Street
United States
Brent
€101
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn St. Louis Arpt West-Earth City by IHG

11. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
1.6 km from Historic Main Street
United States
Tom
€90
includes taxes & fees
9 Aug - 10 Aug
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

12. Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
15.8 km from Historic Main Street
United States
Andrea T
€130
includes taxes & fees
7 Sept - 8 Sept
Drury Plaza Hotel St. Louis Chesterfield

13. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
15.9 km from Historic Main Street
United States
Taylor
€130
includes taxes & fees
30 Aug - 31 Aug
Hyatt Place St. Louis/Chesterfield

14. Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
15.1 km from Historic Main Street
United States
Tenisha
€191
includes taxes & fees
15 Aug - 16 Aug
Residence Inn by Marriott St. Louis Chesterfield

15. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
10.6 km from Historic Main Street
United States
Darren
€92
includes taxes & fees
17 Aug - 18 Aug
Pear Tree Inn St. Louis Airport

16. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
12 km from Historic Main Street
United States
Carlos
€125
includes taxes & fees
17 Aug - 18 Aug
Hyatt Select St. Louis Airport

17. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
10.7 km from Historic Main Street
United States
Gregory
€117
includes taxes & fees
2 Sept - 3 Sept
Wingate by Wyndham St. Louis Airport

18. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
11.3 km from Historic Main Street
United States
Ryan
€117
includes taxes & fees
16 Aug - 17 Aug
Drury Inn & Suites St. Louis Airport

19. Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
15.7 km from Historic Main Street
United States
Serah
€120
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express & Suites St Peters by IHG

20. Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
9.5 km from Historic Main Street
United States
Deoshae
€140
includes taxes & fees
16 Aug - 17 Aug
Fairfield Inn & Suites St Louis Westport
View all properties

Compare popular hotels close to Historic Main Street

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Plaza Hotel St. Louis St. Charles
9.6
Exceptional
1,015 reviews
View
Free daily buffet breakfast
Hampton Inn & Suites St. Charles Old Town Area
9.0
Wonderful
721 reviews
View
Lobby
Embassy Suites by Hilton St. Louis St. Charles
8.8
Excellent
1,005 reviews
View
Exterior
Tru by Hilton St. Charles St. Louis, MO
8.6
Excellent
851 reviews
View
Front of property – evening/night
Hollywood Casino & Hotel St. Louis
8.6
Excellent
2,202 reviews
View

Top Historic Main Street Hotel Reviews

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

8/10 Good
"Room was clean and comfortable. Did not care for the pillows, they were hard. Mini fridge in room but no microwave."
Amanda 1-night trip
Posted 14 hours ago
Hollywood Casino & Hotel St. Louis
Hearth & Harvest | Cozy Farmhouse-Inspired 2BDR

Hearth & Harvest | Cozy Farmhouse-Inspired 2BDR

10/10 Excellent
"This is one place that I would book again and again. Yes, however, the one-bedroom is on the main street, so there's outside noise, but I'm thankful to have a TV to drown out some of the chatter and music from outside. High ceilings great vibes."
George G. 2-night trip
Posted 1 day ago
Hearth & Harvest | Cozy Farmhouse-Inspired 2BDR
The Driftwood Den | Boho-Inspired 2-Bedroom

The Driftwood Den | Boho-Inspired 2-Bedroom

10/10 Excellent
"Great for a family trip. Right on the Main Street for eazy access. Clean and cozy. Will definitely stay again"
Ben E. 3-night trip
Posted 5 days ago
The Driftwood Den | Boho-Inspired 2-Bedroom
The Rustic Revival | Charming 2BR Retreat

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent
"The property was exactly as listed. We enjoyed our stay! We had a question about the battery in the lock and they answered back right away! Definitely recommend!"
Emily Z. 1-night trip
Posted 7 days ago
The Rustic Revival | Charming 2BR Retreat
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

10/10 Excellent
"Beautiful home and was a perfect fit for us. Loved the location so close to the restaurants and shopping. I was surprised there was no oven but we made do. Also came across some small ants. They weren’t really a problem for us but some people may not like them. Just for you to be aware. I would recommend this home to anyone interested in visiting St. Charles. Loved it!!"
Norma R. 3-night trip
Posted 3 weeks ago
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

10/10 Excellent
"The cottage was perfect for my granddaughter and me. It was comfortable, It was nice to have brochures and travel books of the area. Would stay here again"
julie e. 2-night trip
Posted 1 month ago
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
The Oak & Aura Retreat

The Oak & Aura Retreat

10/10 Excellent
"Great location, and very clean! Would stay here again!"
Rachel B. 1-night trip
Posted 2 months ago
The Oak & Aura Retreat
Stylish 2BR Retreat | Concrete & Canopy

Stylish 2BR Retreat | Concrete & Canopy

10/10 Excellent
"The property was very nice and clean. We had issues with checking in due to we had the property address but not a room number. When I called the phone number on the property information sheet the person that answered the phone said the this was no longer the number for the host. My daughter found information on the website with the room number on it. We talked to a couple of other people staying at the same location that had the same problem. Right address with no room number issued. They also had to call with delays checking in. Other than that the property itself was great, Close to everything downtown Old St. Charles. Would stay again, but would like the room number before we arrive at the location."
William T. 2-night trip
Posted 3 months ago
Stylish 2BR Retreat | Concrete & Canopy
The Bourbon & Brass | Speakeasy-Inspired 2BDR

The Bourbon & Brass | Speakeasy-Inspired 2BDR

8/10 Good
"Room was fantastic! The grounds need to be cleaned up a bit."
Marilyn 2-night trip
Posted 4 months ago
The Bourbon & Brass | Speakeasy-Inspired 2BDR

Other attractions near Historic Main Street

A person holding a guitar.
Photo by HA

Frontier Park

You can find out about the history of St. Charles with a stop at Frontier Park. Visit the shops and top-notch restaurants in this family-friendly area.
See properties
A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the acclaimed theatre scene and great live music in this family-friendly area.
See properties

First Missouri State Capitol Historic Site

8.2/10 (25 reviews)
You can learn about the history of St. Charles with a stop at First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theatre scene in this family-friendly area.
See properties

Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Visit the shops and top-notch restaurants in this family-friendly area.
See properties

Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)
You can spend time studying the exhibits at Lewis & Clark Boathouse and Nature Center during your trip to St. Charles. Experience the acclaimed theatre scene and great live music in this family-friendly area.
See properties

Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Visit the shops and top-notch restaurants in this family-friendly area.
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Lindenwood University

8.6/10 (183 reviews)
Enjoy the student vibe at Lindenwood University during your stay in St. Charles. Experience the great live music and acclaimed theatre scene in this family-friendly area.
See properties

St Charles Convention Center

8.4/10 (223 reviews)
After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 108 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Historic Main Street?
Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Hollywood Casino & Hotel St. Louis, located 1.8 mi (3 km) away.
How many hotels are there near Historic Main Street?
Expedia has 108 hotels and other accommodation options within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best options available near Historic Main Street.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main and Historic Aircraft Restoration Museum, you'll experience some of the local culture.