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Houston Hotel Guide. Hotels in South Central Houston, Houston, United States of America

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Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for South Central Houston hotels

A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

1. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.6 out of 10, Excellent, (2,226 reviews)
"The bar/restaurant and staff was excellent."
United States
Stephen
The price is €92
includes taxes & fees
6 Nov - 7 Nov
Hilton Houston Plaza/Medical Center
A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

2. Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (272 reviews)
"Great place and close to downtown."
United States
Israel
The price is €100
includes taxes & fees
29 Oct - 30 Oct
Downtowner Inns - Houston Downtown
A rooftop pool area with lounge chairs and a view of a tall building at night.

3. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,266 reviews)
"Great place"
United States
Matthew
The price is €140
includes taxes & fees
7 Nov - 8 Nov
The Westin Houston Medical Center/Museum District
A modern kitchen with dark wood cabinets, a granite countertop, and a built-in island with a glass enclosure.

4. Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,001 reviews)
"Great Stay"
United States
Randy
The price is €91
includes taxes & fees
28 Oct - 29 Oct
Americas Best Value Inn Medical Center Downtown
A multi-story hotel with a brick facade, balconies, and a well-lit entrance.

5. La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (605 reviews)
"The breakfast was fantastic. Property was clean. Staff is awesome"
United States
Justin
The price is €187
includes taxes & fees
9 Nov - 10 Nov
La Maison in Midtown an urban B&B
A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

6. DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (715 reviews)
"Great place to stay. Convenient to Medical center, clean, quiet, comfortable"
United States
Danny
The price is €119
includes taxes & fees
22 Nov - 23 Nov
DoubleTree by Hilton Houston Medical Center Hotel & Suites
A modern restaurant with a bar area, featuring a patterned floor, multiple dining tables, and contemporary lighting fixtures.

7. Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,004 reviews)
"Was best location to Houston Methodist"
United States
John
The price is €188
includes taxes & fees
22 Nov - 23 Nov
Houston Marriott Medical Center/Museum District
A modern kitchen with a large island, bar stools, and a stainless steel refrigerator.

8. Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (81 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
United States
Sharon
The price is €133
includes taxes & fees
16 Nov - 17 Nov
Wanderstay Boutique Hotel
A modern hotel building with a prominent entrance, large windows, and a visible name sign.

9. InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.4 out of 10, Exceptional, (1,006 reviews)
"Great stay!"
United States
Luke
The price is €186
includes taxes & fees
22 Nov - 23 Nov
InterContinental Houston by IHG
A spacious living area with a dining table, chairs, and a chandelier.

10. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,011 reviews)
"Love this hotel. Been here 4 times. Great pool area, great restaurant, upbeat ambiance. Location is superb for museums and gardens."
United States
Cathy
The price is €318
includes taxes & fees
29 Oct - 30 Oct
Hotel Zaza Houston Museum District
A spacious lobby with a large sectional sofa, a coffee table, and a reception desk.

11. Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (992 reviews)
"Wonderful hotel located on UH campus. Friendly staff and good food on the restaurant"
United States
Diane
The price is €154
includes taxes & fees
23 Nov - 24 Nov
Hilton University of Houston
A hotel room with a bed, a desk, a chair, a mirror, a television, and a heater.

12. Scott Inn Suites - Downtown Houston

Scott Inn Suites - Downtown Houston
2.0 star property
South Central Houston
8.4 out of 10, Very good, (48 reviews)
"great value for money"
United States
Abdulmuiz
The price is €68
includes taxes & fees
29 Oct - 30 Oct
Scott Inn Suites - Downtown Houston
A spacious lobby with a high ceiling, a central seating area with sofas and armchairs, a staircase leading to an upper level, and a flat-screen TV mounted on the wall.

13. Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
6.2 out of 10, (1,006 reviews)
"The perfect place to stay!"
Mexico
Maria Fernanda
The price is €81
includes taxes & fees
29 Oct - 30 Oct
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Private kitchen

14. 2824 Aeon Living

2824 Aeon Living
3.0 star property
South Central Houston
The price is €117
includes taxes & fees
4 Nov - 5 Nov
2824 Aeon Living
A high-rise hotel with a rooftop pool, multiple floors, and a cityscape view.

15. Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (94 reviews)
"Great place to stay!"
United States
Keeshaun
The price is €213
includes taxes & fees
8 Nov - 9 Nov
Sentral Forme Houston
A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.

16. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (221 reviews)
"The room was very clean, the staff was just great and the breakfast was very good! The Parking was a little difficult, but it was very safe!"
United States
Walter
The price is €230
includes taxes & fees
8 Nov - 9 Nov
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
A large outdoor swimming pool with a slide and multiple lanes, surrounded by a modern building with large windows.

17. Fifa Stay 2BR Near NRG DT Med Center -1

Fifa Stay 2BR Near NRG DT Med Center -1
2.0 star property
South Central Houston
Fifa Stay 2BR Near NRG DT Med Center -1
A hotel room with a bed, bedside table, desk, and a mirror.

18. Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (245 reviews)
"Very sweet lady I will be back"
United States
LaKeara
The price is €61
includes taxes & fees
9 Nov - 10 Nov
Southmore Boulevard Motel
A modern reception area with a blackboard, a blue sofa, a yellow armchair, and a colorful rug.

19. Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (219 reviews)
"Excellent stay experience"
United States
Binkeung
The price is €65
includes taxes & fees
28 Oct - 29 Oct
Wanderstay Houston Hostel
A modern kitchen with stainless steel appliances, a granite countertop, and a dining area with a glass table and metal chairs.

20. Walkable Eado Condo Near Dtwn: Modern + Chic!

Walkable Eado Condo Near Dtwn: Modern + Chic!
3.0 star property
South Central Houston
The price is €367
includes taxes & fees
29 Oct - 30 Oct
Walkable Eado Condo Near Dtwn: Modern + Chic!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in South Central Houston

A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

Hilton Houston Plaza/Medical Center

4.5 star property
South Central Houston
View
A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

Downtowner Inns - Houston Downtown

2.0 star property
South Central Houston
View
A rooftop pool area with lounge chairs and a view of a tall building at night.

The Westin Houston Medical Center/Museum District

4.0 star property
South Central Houston
View
A modern kitchen with dark wood cabinets, a granite countertop, and a built-in island with a glass enclosure.

Americas Best Value Inn Medical Center Downtown

2.0 star property
South Central Houston
View
A multi-story hotel with a brick facade, balconies, and a well-lit entrance.

La Maison in Midtown an urban B&B

3.5 star property
South Central Houston
View
8.6
Excellent
2,226 reviews
9.2
Wonderful
272 reviews
9.2
Wonderful
1,266 reviews
8.0
Very good
1,001 reviews
9.8
Exceptional
605 reviews
The price is €92
includes taxes & fees
6 Nov - 7 Nov
The price is €100
includes taxes & fees
29 Oct - 30 Oct
The price is €140
includes taxes & fees
7 Nov - 8 Nov
The price is €91
includes taxes & fees
28 Oct - 29 Oct
The price is €187
includes taxes & fees
9 Nov - 10 Nov
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • No WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families in South Central Houston

A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.6 out of 10, Excellent, (2,226)
The price is €92
includes taxes & fees
6 Nov - 7 Nov
Hilton Houston Plaza/Medical Center

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

10/10 Excellent
"This is probably the cleanest hotel I’ve ever stayed in. Typically, even in a $200 per night hotel the linens on the bed make me feel itchy. Not once did I feel itchy at this hotel."
Julie 1-night trip
Posted 15 hours ago
Downtowner Inns - Houston Downtown

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit TDECU Stadium and Children's Museum of Houston as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveller data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel is a short 6-minute walk from Rice University, and it offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and The Westin Houston Medical Center/Museum District.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1272 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Twilight Epiphany Skyspace. TDECU Stadium and Children's Museum of Houston are some other stops worth a visit in the neighbourhood. Daikin Park and Toyota Center are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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