A water feature with multiple tiers and a circular viewing platform at the top.

Houston Hotel Guide. Hotels in South Central Houston, Houston, United States of America

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Check prices for these dates

This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

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Our top choices for South Central Houston hotels

A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

1. Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (264 reviews)
"Great place and close to downtown."
United States
Israel
The price is €100
includes taxes & fees
25 Oct - 26 Oct
Downtowner Inns - Houston Downtown
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

2. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.6 out of 10, Excellent, (2,204 reviews)
"The bar/restaurant and staff was excellent."
United States
Stephen
The price is €93
includes taxes & fees
22 Nov - 23 Nov
Hilton Houston Plaza/Medical Center
A modern kitchen with dark wood cabinets, a granite countertop, and a built-in island with a glass enclosure.

3. Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,000 reviews)
"Great Stay"
United States
Randy
The price is €103
includes taxes & fees
23 Oct - 24 Oct
Americas Best Value Inn Medical Center Downtown
A spacious living area with a dining table, chairs, and a chandelier.

4. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place!"
United States
Madiha
The price is €315
includes taxes & fees
29 Oct - 30 Oct
Hotel Zaza Houston Museum District
A multi-story hotel with a brick facade, balconies, and a well-lit entrance.

5. La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (604 reviews)
"Lovely welcoming staff, beautiful building with wonderful communal areas. We enjoyed the outside verandah. It's in a fairly noisy location but this didn't bother us. Walking distance to local bars/restaurants, 10 minutes drive to Downtown. Oh and let's not forget the lovely breakfast!"
United Kingdom
Joanna
The price is €186
includes taxes & fees
8 Nov - 9 Nov
La Maison in Midtown an urban B&B
A hotel room with a bed, a desk, a chair, a mirror, a television, and a heater.

6. Scott Inn Suites - Downtown Houston

Scott Inn Suites - Downtown Houston
2.0 star property
South Central Houston
8.4 out of 10, Very good, (47 reviews)
"Nice staff, good clean room and close to public transportation"
United States
Sergio
The price is €70
includes taxes & fees
25 Oct - 26 Oct
Scott Inn Suites - Downtown Houston
A modern restaurant with a bar area, featuring a patterned floor, multiple dining tables, and contemporary lighting fixtures.

7. Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,001 reviews)
"Was best location to Houston Methodist"
United States
John
The price is €187
includes taxes & fees
22 Nov - 23 Nov
Houston Marriott Medical Center/Museum District
A spacious lobby with modern furniture, large windows, and indoor plants.

8. InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.4 out of 10, Exceptional, (1,004 reviews)
"Great stay!"
United States
Luke
The price is €179
includes taxes & fees
22 Nov - 23 Nov
InterContinental Houston by IHG
A bedroom with a bed, a closet, and a door leading to another room.

9. 2824 Aeon Living

2824 Aeon Living
3.0 star property
South Central Houston
The price is €120
includes taxes & fees
28 Oct - 29 Oct
2824 Aeon Living
A modern building with a glass facade and a metal roof structure.

10. Fifa Stay 2BR Near NRG DT Med Center -1

Fifa Stay 2BR Near NRG DT Med Center -1
2.0 star property
South Central Houston
Fifa Stay 2BR Near NRG DT Med Center -1
A high-rise hotel with a rooftop pool, multiple floors, and a cityscape view.

11. Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (93 reviews)
"Great place to stay!"
United States
Keeshaun
The price is €213
includes taxes & fees
8 Nov - 9 Nov
Sentral Forme Houston
A spacious lobby with a large sectional sofa, a coffee table, and a reception desk.

12. Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (990 reviews)
"Wonderful hotel located on UH campus. Friendly staff and good food on the restaurant"
United States
Diane
The price is €161
includes taxes & fees
28 Oct - 29 Oct
Hilton University of Houston
A modern kitchen with a large island, bar stools, and a stainless steel refrigerator.

13. Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (80 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
United States
Sharon
The price is €132
includes taxes & fees
9 Nov - 10 Nov
Wanderstay Boutique Hotel
A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

14. DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (707 reviews)
"Great place to stay. Convenient to Medical center, clean, quiet, comfortable"
United States
Danny
The price is €119
includes taxes & fees
22 Nov - 23 Nov
DoubleTree by Hilton Houston Medical Center Hotel & Suites
A rooftop pool area with lounge chairs and a view of a tall building at night.

15. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,260 reviews)
"Great place"
United States
Matthew
The price is €189
includes taxes & fees
8 Nov - 9 Nov
The Westin Houston Medical Center/Museum District
A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.

16. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (221 reviews)
"The room was very clean, the staff was just great and the breakfast was very good! The Parking was a little difficult, but it was very safe!"
United States
Walter
The price is €229
includes taxes & fees
27 Oct - 28 Oct
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
A hotel room with a bed, bedside table, desk, and a mirror.

17. Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (245 reviews)
"Very sweet lady I will be back"
United States
LaKeara
The price is €61
includes taxes & fees
22 Nov - 23 Nov
Southmore Boulevard Motel
A spacious lobby with a high ceiling, a central seating area with sofas and armchairs, a staircase leading to an upper level, and a flat-screen TV mounted on the wall.

18. Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
6.2 out of 10, (1,000 reviews)
"The perfect place to stay!"
Mexico
Maria Fernanda
The price is €81
includes taxes & fees
12 Nov - 13 Nov
Extended Stay America Suites Houston Med Ctr Braeswood Bl
A modern reception area with a blackboard, a blue sofa, a yellow armchair, and a colorful rug.

19. Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (218 reviews)
"Excellent stay experience"
United States
Binkeung
The price is €65
includes taxes & fees
23 Oct - 24 Oct
Wanderstay Houston Hostel
A basketball court with a wooden floor and red lines, large windows, and a high ceiling with visible ductwork.

20. 2BR Near TSU and Med Center I Assigned Parking 4

2BR Near TSU and Med Center I Assigned Parking 4
2.0 star property
South Central Houston
The price is €213
includes taxes & fees
25 Oct - 26 Oct
2BR Near TSU and Med Center I Assigned Parking 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in South Central Houston

A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

Downtowner Inns - Houston Downtown

2.0 star property
South Central Houston
View
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

Hilton Houston Plaza/Medical Center

4.5 star property
South Central Houston
View
A modern kitchen with dark wood cabinets, a granite countertop, and a built-in island with a glass enclosure.

Americas Best Value Inn Medical Center Downtown

2.0 star property
South Central Houston
View
A spacious living area with a dining table, chairs, and a chandelier.

Hotel Zaza Houston Museum District

4.5 star property
South Central Houston
View
A multi-story hotel with a brick facade, balconies, and a well-lit entrance.

La Maison in Midtown an urban B&B

3.5 star property
South Central Houston
View
9.2
Wonderful
264 reviews
8.6
Excellent
2,204 reviews
8.0
Very good
1,000 reviews
9.2
Wonderful
1,000 reviews
9.8
Exceptional
604 reviews
The price is €100
includes taxes & fees
25 Oct - 26 Oct
The price is €93
includes taxes & fees
22 Nov - 23 Nov
The price is €103
includes taxes & fees
23 Oct - 24 Oct
The price is €315
includes taxes & fees
29 Oct - 30 Oct
The price is €186
includes taxes & fees
8 Nov - 9 Nov
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families in South Central Houston

A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
Houston Central Business District
9.2 out of 10, Wonderful, (264)
The price is €100
includes taxes & fees
25 Oct - 26 Oct
Downtowner Inns - Houston Downtown

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Sentral Forme Houston

Sentral Forme Houston

10/10 Excellent
"Very clean, room w/kirchen, friendly and helpful staff, awesome gym, walking distance to museums. Loved it!"
Francisco 1-night trip
Posted 17 hours ago
Sentral Forme Houston

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit TDECU Stadium and Children's Museum of Houston as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveller data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel is a short 6-minute walk from Rice University, and it offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and The Westin Houston Medical Center/Museum District.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1272 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Twilight Epiphany Skyspace. TDECU Stadium and Children's Museum of Houston are some other stops worth a visit in the neighbourhood. Daikin Park and Toyota Center are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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