La Mesa Guest Houses

A sunset over a mountainous landscape with scattered clouds.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Our top choices for La Mesa guest houses

1. El Primero Hotel

Downtown Chula Vista

Nancy

includes taxes & fees

7 Sept - 8 Sept

2. Vineyard Hacienda

Jamul

Michele

Coffee/tea maker, fridge, microwave, oven

3. Heart of SD | Zoo Nearby | Private Patio | Central

Mid-City

Bronson M.

includes taxes & fees

23 Sept - 24 Sept

4. Somerset

Downtown San Diego

Tyler

1 bedroom, iron/ironing board, free WiFi, bed sheets

5. Modern AC Loft – Private Entry, Free Parking

North Park

Ty S.

includes taxes & fees

22 Sept - 23 Sept

6. Secluded Garden Cottage Walk to Shops + 55” TV

University City

noel o.

includes taxes & fees

1 Sept - 2 Sept

7. Cottage On The Greens - Stunning Golf Course Views

Rancho Bernardo

Janet R.

includes taxes & fees

16 Sept - 17 Sept

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top La Mesa Hotel Reviews

Manchester Grand Hyatt San Diego

10/10 Excellent

"Beautiful hotel impeccably maintained. Excellent service. Pool is being refurbished so didn’t use. Roof top bar was really fun and relaxed."

Handlery Hotel

10/10 Excellent

"We were super impressed with our stay at this Resort. The rooms were a little outdated but you can't beat the price for what you get. The pool music was a bit loud and started playing early in the morning, but we were there to drink, eat and enjoy the pool and not spend all day sleeping. The lounge bar beside the pool was a bit over priced but convenience and excellent. The happy hour specials were a bonus that we took full advantage of. Food was excellent and make sure you try the sushi which was a hit with the whole family. Would definitely stay here again."

The Sofia Hotel

10/10 Excellent

"Our room was very clean and comfortable. The hotel itself is very charming. The staff was incredibly helpful and friendly. They have a large carafe of complementary flavored water at the desk. One day it was watermelon another day it was cucumber celery. I like the location of the hotel also, it's not too far from a grocery store. There are different restaurants and places to eat very close."

Find out more about La Mesa