Springfield Hotel Guide - Lester E. Cox Medical Center South hotels in Springfield, United States of America.

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15 Dec - 16 Dec
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16 Dec - 17 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Lester E. Cox Medical Center South hotels

Terrace/patio
Homewood Suites by Hilton Springfield Medical District

Homewood Suites by Hilton Springfield Medical District

Homewood Suites by Hilton Springfield Medical District
3.0 star property
1.4 km from Lester E. Cox Medical Center South
9.4 out of 10, Exceptional, (457)
"Beautiful room and very friendly staff"
United States
Amanda
The price is €104
includes taxes & fees
21 Dec - 22 Dec
Homewood Suites by Hilton Springfield Medical District
Free daily buffet breakfast
Holiday Inn Express and Suites Springfield Medical District by IHG

Holiday Inn Express and Suites Springfield Medical District by IHG

Holiday Inn Express and Suites Springfield Medical District by IHG
3.0 star property
1.6 km from Lester E. Cox Medical Center South
9.4 out of 10, Exceptional, (949)
"Very clean, courteous staff, good breakfast!"
United States
Jason
The price is €107
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express and Suites Springfield Medical District by IHG
Lobby lounge
Hampton Inn Springfield-South

Hampton Inn Springfield-South

Hampton Inn Springfield-South
2.5 star property
Galloway Village, 2 km from Lester E. Cox Medical Center South
9.4 out of 10, Exceptional, (609)
"Breakfast and bed great."
United States
Gregory
The price is €92
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Springfield-South
In-room safe, desk, iron/ironing board, free WiFi
Candlewood Suites Springfield-Medical District

Candlewood Suites Springfield-Medical District

Candlewood Suites Springfield-Medical District
2.5 star property
0.9 km from Lester E. Cox Medical Center South
9.2 out of 10, Wonderful, (410)
"Ashley was so friendly and helpful. The room had everything I needed for the week. A lovely stay!"
United States
Kimberly Laine
The price is €107
includes taxes & fees
28 Dec - 29 Dec
Candlewood Suites Springfield-Medical District
Lobby
Element Springfield South

Element Springfield South

Element Springfield South
3.0 star property
Meador Park, 1.5 km from Lester E. Cox Medical Center South
9.2 out of 10, Wonderful, (97)
"Meticulously clean, comfortable, quiet, very friendly and helpful staff. I travel frequently and this was one of the best hotel stays. "
United States
Tonya
The price is €106
includes taxes & fees
4 Jan - 5 Jan 2026
Element Springfield South
Property amenity
Residence Inn by Marriott Springfield

Residence Inn by Marriott Springfield

Residence Inn by Marriott Springfield
3.0 star property
0.8 km from Lester E. Cox Medical Center South
9.0 out of 10, Wonderful, (956)
"Very friendly staff. Cleanliness of whole facility. Good breakfast. The bed was very firm, almost hard. Other than that it was great!"
United States
Becky
The price is €114
includes taxes & fees
20 Dec - 21 Dec
Residence Inn by Marriott Springfield
Lobby
MainStay Suites Springfield South - Battlefield Rd

MainStay Suites Springfield South - Battlefield Rd

MainStay Suites Springfield South - Battlefield Rd
2.0 star property
Bradford Park, 1.7 km from Lester E. Cox Medical Center South
9.0 out of 10, Wonderful, (82)
"Clean, friendly"
United States
joe
The price is €81
includes taxes & fees
1 Jan - 2 Jan 2026
MainStay Suites Springfield South - Battlefield Rd
Front of property
Hilton Garden Inn Springfield, MO

Hilton Garden Inn Springfield, MO

Hilton Garden Inn Springfield, MO
3.0 star property
2.7 km from Lester E. Cox Medical Center South
9.0 out of 10, Wonderful, (818)
"Comfortable beds, nice staff"
United States
Jennifer
The price is €101
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn Springfield, MO
Room, 2 Queen Beds, Non Smoking
La Quinta Inn & Suites by Wyndham Springfield South

La Quinta Inn & Suites by Wyndham Springfield South

La Quinta Inn & Suites by Wyndham Springfield South
3.0 star property
Seminole Holland, 2.8 km from Lester E. Cox Medical Center South
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay"
United States
Frank
The price is €87
includes taxes & fees
25 Dec - 26 Dec
La Quinta Inn & Suites by Wyndham Springfield South
Exterior
The Bradford Hotel, an Ascend Collection Hotel

The Bradford Hotel, an Ascend Collection Hotel

The Bradford Hotel, an Ascend Collection Hotel
2.5 star property
Bradford Park, 0.5 km from Lester E. Cox Medical Center South
8.6 out of 10, Excellent, (231)
"The room was clean and scent free. I would stay here again."
United States
Jordana
The price is €76
includes taxes & fees
25 Dec - 26 Dec
The Bradford Hotel, an Ascend Collection Hotel
Free daily full breakfast
Comfort Inn South - Springfield

Comfort Inn South - Springfield

Comfort Inn South - Springfield
2.5 star property
Galloway Village, 2.3 km from Lester E. Cox Medical Center South
8.6 out of 10, Excellent, (1010)
"Nice room, friendly staff "
United States
James
The price is €86
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn South - Springfield
Lobby
Sleep Inn Springfield South I60 near Medical District

Sleep Inn Springfield South I60 near Medical District

Sleep Inn Springfield South I60 near Medical District
3.0 star property
1.8 km from Lester E. Cox Medical Center South
8.2 out of 10, Very good, (801)
"Staff was friendly, room was very clean."
United States
Barbara
The price is €85
includes taxes & fees
4 Jan - 5 Jan 2026
Sleep Inn Springfield South I60 near Medical District
Desk, free WiFi, bed sheets
Extended Stay America Select Suites Springfield South

Extended Stay America Select Suites Springfield South

Extended Stay America Select Suites Springfield South
2.5 star property
0.9 km from Lester E. Cox Medical Center South
6.6 out of 10, (1001)
"The kitchen was amazing "
United States
Brandy
The price is €77
includes taxes & fees
18 Dec - 19 Dec
Extended Stay America Select Suites Springfield South
Lobby
Hampton Inn Springfield-Southeast

Hampton Inn Springfield-Southeast

Hampton Inn Springfield-Southeast
2.5 star property
Galloway Village, 4.9 km from Lester E. Cox Medical Center South
9.4 out of 10, Exceptional, (797)
"The breakfast was very good and the area clean.Those Waffles are great."
United States
Janice
The price is €97
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Springfield-Southeast
Suite, 1 Queen Bed
Walnut Street Inn

Walnut Street Inn

Walnut Street Inn
3.5 star property
Walnut Street, 6.7 km from Lester E. Cox Medical Center South
9.4 out of 10, Exceptional, (207)
"Loved our stay here!"
United States
Mary
The price is €109
includes taxes & fees
16 Dec - 17 Dec
Walnut Street Inn
Front of property
TownePlace Suites Springfield

TownePlace Suites Springfield

TownePlace Suites Springfield
3.0 star property
Seminole Holland, 3.5 km from Lester E. Cox Medical Center South
9.2 out of 10, Wonderful, (603)
"Great place to stay"
United States
Amy
The price is €93
includes taxes & fees
26 Dec - 27 Dec
TownePlace Suites Springfield
Lobby
Tru by Hilton Springfield Downtown

Tru by Hilton Springfield Downtown

Tru by Hilton Springfield Downtown
2.5 star property
Downtown Springfield, 6.6 km from Lester E. Cox Medical Center South
9.2 out of 10, Wonderful, (891)
"Awesome stay! Will stay here again when traveling. "
United States
Jacqueline
The price is €100
includes taxes & fees
21 Dec - 22 Dec
Tru by Hilton Springfield Downtown
Room, 1 King Bed, Balcony
Hotel Vandivort

Hotel Vandivort

Hotel Vandivort
4.0 star property
Downtown Springfield, 6.8 km from Lester E. Cox Medical Center South
9.2 out of 10, Wonderful, (1001)
"Friendly staff. Great dining place close by. "
United States
Kathleen
The price is €164
includes taxes & fees
28 Dec - 29 Dec
Hotel Vandivort
Lobby
SpringHill Suites by Marriott Springfield North

SpringHill Suites by Marriott Springfield North

SpringHill Suites by Marriott Springfield North
2.5 star property
Parkwood, 11.6 km from Lester E. Cox Medical Center South
9.4 out of 10, Exceptional, (762)
"Nice hotel and good value"
United States
Robert
The price is €97
includes taxes & fees
21 Dec - 22 Dec
SpringHill Suites by Marriott Springfield North
Exterior
Holiday Inn Express & Suites Springfield North by IHG

Holiday Inn Express & Suites Springfield North by IHG

Holiday Inn Express & Suites Springfield North by IHG
2.5 star property
11.8 km from Lester E. Cox Medical Center South
9.4 out of 10, Exceptional, (1004)
"Very friendly front desk, clean room and guest areas. "
United States
armando
The price is €86
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Springfield North by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lester E. Cox Medical Center South Hotel Reviews

Comfort Inn South - Springfield

Comfort Inn South - Springfield

10/10 Excellent
"Nice,clean,friendly place.We always stay here when we go to Springfield."
Martha 2-night trip
Posted 4 days ago
Comfort Inn South - Springfield

Hotels near other Lester E. Cox Medical Center South attractions

Caption---- Springfield Nature Center

Springfield Conservation Nature Center

Enjoy a stop at Springfield Conservation Nature Center, an entertaining place to visit in Springfield. You can attend a sporting event while in the area.
See properties
A butterfly at the Butterfly Housr
Photo by Pat Long
Open Photo by Pat Long

Nathanael Greene/Close Memorial Park

4.7/5 (16 reviews)
Explore the great outdoors at Nathanael Greene/Close Memorial Park, a lovely green space in Springfield. Experience the area's entertainment choices or attend a sporting event.
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Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?
Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travellers like for its sporting events and opera houses. If you're looking for a convenient place to stay, take a look at the 13 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Lester E. Cox Medical Center South?
Residence Inn by Marriott Springfield is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Lester E. Cox Medical Center South. Other good choices close by include The Bradford Hotel, an Ascend Collection Hotel and Homewood Suites by Hilton Springfield Medical District.
How many hotels are there close to Lester E. Cox Medical Center South?
Expedia has 13 hotels and other accommodation options within a mile from Lester E. Cox Medical Center South.
If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to review the best deals available near Lester E. Cox Medical Center South.
What can I see and do near Lester E. Cox Medical Center South?
You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

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