The entrance to the Kentucky Science Center with a large circular structure in the foreground.

Louisville Hotel Guide - Louisville Science Center hotels in Louisville, United States of America.

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Check prices for these dates

Tonight
10 Oct - 11 Oct
Tomorrow
11 Oct - 12 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

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Our top choices for Louisville Science Center hotels

A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand lobby with ornate ceiling, large windows, and classic furniture.

1. The Brown Hotel

The Brown Hotel
Downtown Louisville, 1.2 km from Louisville Science Center
United States
John
€132
includes taxes & fees
28 Oct - 29 Oct
The Brown Hotel
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.
A room with a red velvet sofa, a blue armchair, and a small round table with books.
A living room with a sofa, a fireplace, a staircase, and a chandelier.

2. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
Old Louisville, 2.8 km from Louisville Science Center
United States
Casey
€189
includes taxes & fees
14 Oct - 15 Oct
DuPont Mansion Bed & Breakfast
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.
A bar with shelves of liquor bottles and a bartender preparing drinks.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

3. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Anthony
€249
includes taxes & fees
29 Oct - 30 Oct
Hotel Distil, Autograph Collection
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.
A spacious lobby with a large seating area, a chandelier, and a patterned rug.
A swimming pool with lounge chairs and a view of the city.

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville, 0.2 km from Louisville Science Center
United States
Kelly
€129
includes taxes & fees
29 Oct - 30 Oct
Homewood Suites by Hilton Louisville Downtown, KY
A modern bar area with a circular bar, multiple seating options, and a large screen.
A modern lobby with a fireplace, seating area, and a reception desk.
A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.
A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.

5. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
Downtown Louisville, 1.2 km from Louisville Science Center
United States
Gordon
€113
includes taxes & fees
9 Nov - 10 Nov
Cambria Hotel Louisville Downtown-Whiskey Row
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A building with a sign reading "THE GRADY" at the entrance.
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

6. The Grady

The Grady
Downtown Louisville, 0.2 km from Louisville Science Center
United States
Donna
€195
includes taxes & fees
18 Oct - 19 Oct
The Grady
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.
A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

7. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
Phoenix Hill, 2.1 km from Louisville Science Center
United States
Addison
€128
includes taxes & fees
25 Oct - 26 Oct
Tempo By Hilton Louisville Downtown Nulu
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A steam fountain in a brick alleyway.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville, < 0.1 km from Louisville Science Center
United States
Matt
€173
includes taxes & fees
8 Nov - 9 Nov
21c Museum Hotel Louisville
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern interior with a fireplace, bookshelves, and seating areas.

9. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Samantha
€267
includes taxes & fees
30 Oct - 31 Oct
Omni Louisville Hotel
A covered patio with a stone wall, a glass table, and a bench.
A stone house with a balcony, a front door, and a staircase leading to the entrance.
A grand room with a fireplace, a staircase, and a chandelier.
Staircase

10. Central Park Bed & Breakfast

Central Park Bed & Breakfast
Old Louisville, 3 km from Louisville Science Center
United States
Brittany
€177
includes taxes & fees
11 Oct - 12 Oct
Central Park Bed & Breakfast
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

11. Stellar Suites

Stellar Suites
East Market District, 2.2 km from Louisville Science Center
United States
Kevin
€169
includes taxes & fees
18 Oct - 19 Oct
Stellar Suites
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Cameron
€189
includes taxes & fees
18 Oct - 19 Oct
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
An outdoor seating area with wicker furniture and a fire pit.
A modern living room with a sofa, armchairs, a coffee table, and a TV.
An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.
A modern lounge area with seating, tables, and a view of the city through large windows.

13. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
Downtown Louisville, 0.3 km from Louisville Science Center
United States
Derek
€110
includes taxes & fees
5 Nov - 6 Nov
Towneplace Suites By Marriott Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.
A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.
A modern bar area with sofas, tables, and a bar stocked with bottles.
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

14. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Dolores
€142
includes taxes & fees
8 Nov - 9 Nov
Aloft by Marriott Louisville Downtown
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.
A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.
A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

15. Moxy Louisville Downtown

Moxy Louisville Downtown
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Bryan
€134
includes taxes & fees
25 Oct - 26 Oct
Moxy Louisville Downtown
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.
A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.
A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.

16. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
East Market District, 2.1 km from Louisville Science Center
United States
Jen
€150
includes taxes & fees
25 Oct - 26 Oct
AC Hotel Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A balcony with a view of a river, a bridge, and a cityscape.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

17. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville, 0.5 km from Louisville Science Center
United States
Saud
€152
includes taxes & fees
25 Oct - 26 Oct
Galt House Hotel Trademark Collection by Wyndham
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A brightly lit grocery store with yellow shelving and a central checkout counter.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.
A bedroom with a bed, a chair, a TV, and a window with curtains.

18. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
East Market District, 2.1 km from Louisville Science Center
United States
Tyler
€152
includes taxes & fees
26 Oct - 27 Oct
Hotel Genevieve part of JdV by Hyatt
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A hotel dining area with long tables, booths, and a bar.

19. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Frances
€154
includes taxes & fees
29 Oct - 30 Oct
Embassy Suites Louisville Downtown
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A reception area with marble counters, modern pendant lighting, and potted orchids.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

20. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Veronica
€234
includes taxes & fees
7 Nov - 8 Nov
Louisville Marriott Downtown
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Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
9.4
Exceptional
1,358 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
9.6
Exceptional
148 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
9.6
Exceptional
508 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
9.4
Exceptional
1,002 reviews
View
A modern bar area with a circular bar, multiple seating options, and a large screen.
Cambria Hotel Louisville Downtown-Whiskey Row
9.4
Exceptional
1,004 reviews
View

Top Louisville Science Center Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"The staff was very friendly and acknowledged us at the front desk and while walking through the hotel. Breakfast was cooked to order and hot. Very friendly dining room staff. Bedroom and bathroom were clean and very nicely organized and decorated."
Thomas 2-night trip
Posted 3 hours ago
Galt House Hotel Trademark Collection by Wyndham
Moxy Louisville Downtown

Moxy Louisville Downtown

8/10 Good
"Loved the location and street parking options…"
Alicia 5-night trip
Posted 3 hours ago
Moxy Louisville Downtown
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

8/10 Good
"Great location in downtown Louisville. Close to Whiskey Row and many restaurants. We did not have a car so did not use parking. Breakfast was fine for a free hotel breakfast. Had a light bulb that was out and they promote put a new one in. Room size was great."
Kathy 3-night trip
Posted 4 hours ago
Holiday Inn Express & Suites Louisville Downtown by IHG
The Brown Hotel

The Brown Hotel

10/10 Excellent
"Arrived after early flight and were able to go straight to our room even though it was still morning. Hotel service was spot on including a great ride in airport shuttle with Doug. Definitely would stay here again."
Patrick 1-night trip
Posted 4 hours ago
The Brown Hotel
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

10/10 Excellent
"Great hotel!"
Gordon 1-night trip
Posted 1 day ago
Cambria Hotel Louisville Downtown-Whiskey Row
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

8/10 Good
"Staff were great. Breakfast was good. Only is was the fan in the bathroom. It had a banging noise coming from it and if you left the door open it would keep you awake."
Robert 6-night trip
Posted 1 day ago
Towneplace Suites By Marriott Louisville Downtown
Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG

8/10 Good
"The room was very small. Had hoped that myself and husband could work remote in room, but that was impossible due to tiny space. He was able to work downstairs in lobby, but not ideal. Unable to get served at on-site restaurant. One person taking orders, cooking and serving during busy time of day. The person's working at checking and in on-site bar area were very helpful. Coffee and water were not kept filled in lobby area. A little disappointed in this. Good location near 4th Street Live area. Parking location is across the street if you don't want to pay valet fee."
Tracy 1-night trip
Posted 1 day ago
Holiday Inn Louisville Downtown by IHG
The Reserve on Main

The Reserve on Main

10/10 Excellent
"All good."
Jason 2-night trip
Posted 12 days ago
The Reserve on Main
4 Bed, 3 Bath Loft in Downtown Louisville! Amazing River Views! Private Deck!

4 Bed, 3 Bath Loft in Downtown Louisville! Amazing River Views! Private Deck!

8/10 Good
"Clean, great space, spacious. The room in the loft can be hot if it’s hot and sunny outside and there is no bathroom on that level. Otherwise, highly recommend, especially for adults where rooms are separated which gives a little privacy."
Suzette R. 3-night trip
Posted 3 weeks ago
4 Bed, 3 Bath Loft in Downtown Louisville! Amazing River Views! Private Deck!

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)
Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.
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The Kentucky Center for the Performing Arts building facade with large glass windows and a prominent sign.

Kentucky Center for the Performing Arts

8.8/10 (49 reviews)
Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.
See properties

Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.
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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.