Lodging Image

Fort Pierce Hotel Guide. Hotels in Main Street Fort Pierce, Fort Pierce, United States of America

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
24 Jul - 26 Jul
Next weekend
31 Jul - 2 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Main Street Fort Pierce hotels

Outdoor spa tub

1. Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.2 out of 10, Very good, (1,394 reviews)
"Staff was very nice . Would come back again for sure"
United States
Jack
The price is €125
includes taxes & fees
30 Jul - 31 Jul
Hutchinson Island Hotel
Free WiFi, individually decorated, individually furnished, bed sheets

2. Redfinn Inn

Redfinn Inn
2.5 star property
0.7 km from Main Street Fort Pierce
6.4 out of 10, (410 reviews)
"Goog"
United States
Eric
The price is €66
includes taxes & fees
23 Jul - 24 Jul
Redfinn Inn
Lobby

3. Hampton Inn & Suites Ft. Pierce

Hampton Inn & Suites Ft. Pierce
2.5 star property
7.9 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1,000 reviews)
"Hotel was very beautiful and very clean Room was clean, breakfast was delicious"
United States
Karen
The price is €88
includes taxes & fees
9 Aug - 10 Aug
Hampton Inn & Suites Ft. Pierce
Restaurant

4. Days Inn & Suites by Wyndham Fort Pierce Midtown

Days Inn & Suites by Wyndham Fort Pierce Midtown
2.0 star property
4.5 km from Main Street Fort Pierce
7.0 out of 10, Good, (1,000 reviews)
"Quiet, clean, friendly staff"
United States
David
The price is €68
includes taxes & fees
26 Jul - 27 Jul
Days Inn & Suites by Wyndham Fort Pierce Midtown
On the beach

5. Oceanfront Inn II

Oceanfront Inn II
2.0 star property
4 km from Main Street Fort Pierce
8.0 out of 10, Very good, (69 reviews)
"Had a excellent stay"
United States
Dennis
The price is €161
includes taxes & fees
16 Aug - 17 Aug
Oceanfront Inn II
Lobby

6. Rodeway Inn Fort Pierce US Highway 1

Rodeway Inn Fort Pierce US Highway 1
2.0 star property
2.9 km from Main Street Fort Pierce
6.8 out of 10, (121 reviews)
"Clean room, convenient location"
United States
Natalia
The price is €75
includes taxes & fees
28 Jul - 29 Jul
Rodeway Inn Fort Pierce US Highway 1
Lobby

7. Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
3.0 star property
7.7 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1,000 reviews)
"This hotel was really good, the staff there were really helpful and the breakfast options were nice as well. The location was perfect and near major retailers and restaurants as well as not too far from the beach."
United States
Nilam
The price is €91
includes taxes & fees
18 Aug - 19 Aug
Fairfield Inn & Suites by Marriott Fort Pierce
Superior Room, 1 King Bed, Non Smoking | Property grounds

8. Red Roof Inn Ft Pierce

Red Roof Inn Ft Pierce
2.0 star property
4.6 km from Main Street Fort Pierce
7.2 out of 10, Good, (808 reviews)
"for me it was the location and friendly staff rooms were decent and clean for a motel bathroom fixtures area a little outdated but has improved from previous stays overall improvement"
United States
Michael
The price is €78
includes taxes & fees
29 Jul - 30 Jul
Red Roof Inn Ft Pierce
Terrace/patio

9. Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
7.8 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (257 reviews)
"Clean room great staff and amazing breakfast "
United States
Shaleek
The price is €112
includes taxes & fees
12 Aug - 13 Aug
Home2 Suites by Hilton Ft. Pierce I-95
Lobby

10. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
2.5 star property
8.3 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (869 reviews)
"Great place to stay."
United States
Melissa
The price is €97
includes taxes & fees
9 Aug - 10 Aug
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
Lobby

11. Sleep Inn Fort Pierce I-95

Sleep Inn Fort Pierce I-95
2.5 star property
7.9 km from Main Street Fort Pierce
7.6 out of 10, Good, (892 reviews)
"Parking was safe and easy ."
United States
Thomas
The price is €73
includes taxes & fees
9 Aug - 10 Aug
Sleep Inn Fort Pierce I-95
Front of property

12. At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.0 out of 10, Very good, (1,218 reviews)
"Perfect quick stay!"
United States
Catherine
The price is €69
includes taxes & fees
26 Jul - 27 Jul
At Home Inn
Pillow-top beds, desk, blackout curtains, iron/ironing board

13. Comfort Suites Fort Pierce I-95

Comfort Suites Fort Pierce I-95
2.5 star property
7.7 km from Main Street Fort Pierce
7.8 out of 10, Good, (946 reviews)
"Perfect breakfast and room"
United States
Nair
The price is €85
includes taxes & fees
26 Jul - 27 Jul
Comfort Suites Fort Pierce I-95
Lobby

14. Days Inn & Suites by Wyndham Fort Pierce I-95

Days Inn & Suites by Wyndham Fort Pierce I-95
2.5 star property
7.8 km from Main Street Fort Pierce
7.4 out of 10, Good, (1,001 reviews)
"Clean rooms - great hotel to stay at!"
United States
Richard
The price is €78
includes taxes & fees
26 Jul - 27 Jul
Days Inn & Suites by Wyndham Fort Pierce I-95
On the beach

15. Oceanfront Inn

Oceanfront Inn
2.0 star property
4 km from Main Street Fort Pierce
8.0 out of 10, Very good, (38 reviews)
"Always enjoy staying here! Will be back soon..."
United States
Thomas
The price is €182
includes taxes & fees
6 Aug - 7 Aug
Oceanfront Inn
Outdoor pool, pool loungers

16. Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
14 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,000 reviews)
"Pleasantly surprised nice room for our stop over"
United States
Michael
The price is €84
includes taxes & fees
10 Aug - 11 Aug
Best Western Port St. Lucie
Exterior

17. Oceanfront Inn

Oceanfront Inn
2.0 star property
4 km from Main Street Fort Pierce
6.0 out of 10, (6 reviews)
"Room was a bit dated but spotless, the staff excellent, fabulous location and views. Only drawback was the beach had suffered storm erosion and it and the beach bar was closed. Jetty park and beautiful beaches very close by. The restaurant, a separate attached business, was always hopping with great food and extensive bar with excellent staff. I expect to return many times. "
United States
George
The price is €151
includes taxes & fees
4 Aug - 5 Aug
Oceanfront Inn
Free daily on-the-go breakfast

18. Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West
2.5 star property
17.4 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1,004 reviews)
"Great stay 10/10!"
United States
Lauren
The price is €76
includes taxes & fees
21 Aug - 22 Aug
Hampton Inn & Suites Port St. Lucie, West
Reception

19. Crossroads Inn

Crossroads Inn
8.1 km from Main Street Fort Pierce
8.0 out of 10, Very good, (5 reviews)
"Good"
United States
Sirjames
The price is €62
includes taxes & fees
23 Jul - 24 Jul
Crossroads Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas for the activities you enjoy most.
A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

When in Lakewood Park, you can plan a visit to Lakewood Park Regional Park / Pool and McKee Botanical Garden, some noteworthy sights in the nearby area.

Spanish Lakes Country Club Village

While Spanish Lakes Country Club Village isn't home to many top sights, Lakewood Park Regional Park / Pool and Harbor Branch Ocean Discovery Center are some notable places to visit nearby.

A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While there might not be top attractions in Spanish Lakes Fairways, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

While Meadowood isn't home to many top sights, Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery are some notable places to visit nearby.

A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

While Panther Woods may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Endless Summer Vineyard & Winery.

Top Main Street Fort Pierce Hotel Reviews

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

8/10 Good
"Professional"
Jude 3-night trip
Posted 10 hours ago
Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighbourhood that travellers like for its waterfront, art and shopping. Make sure that you visit Sunrise Theater and Fort Pierce City Marina as part of your Main Street Fort Pierce travel plans.
How many hotels will I find in Main Street Fort Pierce?
Book one of Expedia's 7 hotels and other accommodation options in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best options available in Main Street Fort Pierce.
What is there to do in this Fort Pierce neighbourhood?
Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce City Marina and Fort Pierce Farmer's Market are also a couple of places to visit in the neighbourhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.