Hotel Guide - Main Street hotels in , United States of America.

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street hotels

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
9.6 km from Main Street
9.4 out of 10, Exceptional, (1,000 reviews)
"Very nice stay"
United States
Robert
The price is €146
includes taxes & fees
18 Feb - 19 Feb
Anchor In Distinctive Waterfront Lodging

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
9.1 km from Main Street
8.8 out of 10, Excellent, (677 reviews)
"Excellent staff-clean rooms-great location"
United States
Patrice
The price is €119
includes taxes & fees
22 Feb - 23 Feb
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Sea Street Inn

Sea Street Inn
4.0 star property
8 km from Main Street
9.8 out of 10, Exceptional, (45 reviews)
"Very nicely renovated small property with a fantastic breakfast."
United States
Paul
The price is €222
includes taxes & fees
18 Feb - 19 Feb
Sea Street Inn

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
9.2 km from Main Street
8.8 out of 10, Excellent, (492 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is €131
includes taxes & fees
1 Mar - 2 Mar
Courtyard By Marriott Cape Cod Hyannis

The Club at New Seabury

The Club at New Seabury
3.5 star property
10.3 km from Main Street
9.0 out of 10, Wonderful, (350 reviews)
"Everything was superb, accommodations, check in service, check out service!!"
United States
Dianna
The price is €158
includes taxes & fees
19 Feb - 20 Feb
The Club at New Seabury

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
8.9 km from Main Street
8.2 out of 10, Very good, (989 reviews)
"Great place to stay "
United States
Lilian
The price is €110
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Hyannis by IHG

Courtyard Resort

Courtyard Resort
2.0 star property
8.8 km from Main Street
8.4 out of 10, Very good, (58 reviews)
"It was ok. Best part was it was near everything. "
United States
Kimberly
The price is €105
includes taxes & fees
18 Feb - 19 Feb
Courtyard Resort

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
11.2 km from Main Street
8.8 out of 10, Excellent, (1,546 reviews)
"The place was clean, staff very nice and a good breakfast! Nice pool and beach area."
United States
LisaAnn
The price is €100
includes taxes & fees
25 Feb - 26 Feb
Bayside Resort Hotel

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
10.9 km from Main Street
9.4 out of 10, Exceptional, (111 reviews)
"Clean, nice staff, good amenities, central location"
United States
Malbis
The price is €117
includes taxes & fees
27 Feb - 28 Feb
Uncommoner Hotel by Reverie Boutique Collection

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
9.4 km from Main Street
8.0 out of 10, Very good, (1,002 reviews)
"Nice hotel had a perfect stay"
United States
David
The price is €88
includes taxes & fees
26 Feb - 27 Feb
Comfort Inn Hyannis - Cape Cod

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
8.7 km from Main Street
8.8 out of 10, Excellent, (449 reviews)
"The interior of the rooms were clean, the staff was friendly. "
United States
Maria Luisa
The price is €169
includes taxes & fees
18 Feb - 19 Feb
Margaritaville Resort Cape Cod

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
10.7 km from Main Street
8.8 out of 10, Excellent, (1,000 reviews)
"They were excellent. Felt extremely comfortable. Their breakfast was amazing, staff were so friendly!"
United States
Linda
The price is €102
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn & Suites Cape Cod-West Yarmouth

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
9.8 km from Main Street
8.4 out of 10, Very good, (891 reviews)
"It was a decent stay I can’t complain "
United States
Rony
The price is €126
includes taxes & fees
1 Mar - 2 Mar
Doubletree by Hilton Cape Cod - Hyannis

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
12.4 km from Main Street
8.0 out of 10, Very good, (1,003 reviews)
"Great place "
United States
Lilian
The price is €79
includes taxes & fees
24 Feb - 25 Feb
Aiden by Best Western Cape Cod - West Yarmouth

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
9.3 km from Main Street
8.4 out of 10, Very good, (20 reviews)
"It was ok staff was nice"
United States
Troy
The price is €93
includes taxes & fees
23 Feb - 24 Feb
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Cape Sands Inn

Cape Sands Inn
2.5 star property
11 km from Main Street
8.2 out of 10, Very good, (1,022 reviews)
"Room was nice and spacious, very clean. Upstairs people was a little loud but other than that the stay was good. Would definitely stay again. "
United States
Celestina
The price is €72
includes taxes & fees
18 Feb - 19 Feb
Cape Sands Inn

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
9.1 km from Main Street
8.0 out of 10, Very good, (1,001 reviews)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is €155
includes taxes & fees
26 Feb - 27 Feb
Hyannis Harbor Hotel

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
7.9 km from Main Street
7.8 out of 10, Good, (193 reviews)
"Nice place to stay "
United States
Kevin
The price is €86
includes taxes & fees
18 Feb - 19 Feb
Sea Breeze Inn

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
11.2 km from Main Street
9.2 out of 10, Wonderful, (251 reviews)
"Was unaware that pool facilities were closed for 2 weeks of maintenance which was primary purpose of stay"
United States
Edward
The price is €124
includes taxes & fees
23 Feb - 24 Feb
The Cove at Yarmouth by Westgate Resorts

Cape Cod Hotel

Cape Cod Hotel
2.5 star property
8.8 km from Main Street
7.4 out of 10, Good, (1,000 reviews)
"Room was clean and what we needed. Very comfortable. Breakfast options were nice. Pancakes, scrambled eggs, potatoes and a variety of yogurt among a few other danishes. Enjoyed our stay. "
United States
Matthew
The price is €100
includes taxes & fees
23 Feb - 24 Feb
Cape Cod Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Main Street

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Interior entrance
Anchor In Distinctive Waterfront Lodging
3.0 star property
9.4
Exceptional
1,000 reviews
View
Lobby
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
8.8
Excellent
677 reviews
View
Dining
Sea Street Inn
4.0 star property
9.8
Exceptional
45 reviews
View
Indoor pool
Courtyard By Marriott Cape Cod Hyannis
3.0 star property
8.8
Excellent
492 reviews
View
Meeting facility
The Club at New Seabury
3.5 star property
9.0
Wonderful
350 reviews
View

Top Main Street Hotel Reviews

Hotels near other Main Street attractions

Frequently asked questions

What's the area like around Main Street?
If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, take a look at the 25 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Main Street?
Long Dell Inn is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. It's located 2.5 mi (4.1 km) from Main Street. Other good choices within 5 miles include The Ocean View and Captain David Kelley House Bed & Breakfast.
How many hotels will I be able to find near Main Street?
Expedia has 25 hotels and other accommodation options within a mile from Main Street.
If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best options available near Main Street.
What can I see and do near Main Street?
Study the collections at Centerville Historical Museum, Cahoon Museum of American Art or Toad Hall Classic Sports Car Museum. You can check out the local talent at Cotuit Center for the Arts, Cape Cod Melody Tent and Barnstable Performing Arts Center. Dip your toes in the water at Craigville Beach, Keyes Beach and Dowses Beach.