A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.

Hyannis Hotel Guide - Main Street Hyannis hotels in Hyannis, United States of America.

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Check prices for these dates

This weekend
10 Jul - 12 Jul
Next weekend
17 Jul - 19 Jul

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Our top choices for Main Street Hyannis hotels

Luxury King Room

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (46 reviews)
"Very nicely renovated small property with a fantastic breakfast."
United States
Paul
The price is €409
includes taxes & fees
15 Jul - 16 Jul
Sea Street Inn
Indoor pool, seasonal outdoor pool

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (204 reviews)
"Great place to stay and the staff members are amazing."
United States
Joseph
The price is €287
includes taxes & fees
14 Jul - 15 Jul
Uncommoner Hotel by Reverie Boutique Collection
Exterior

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (54 reviews)
"Great location, clean …we love it!!!!!"
United States
Aloisio
The price is €179
includes taxes & fees
2 Aug - 3 Aug
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Marina

Cape Cod Inn

Cape Cod Inn
2.0 star property
0.2 km from Main Street Hyannis
8.6 out of 10, Excellent, (523 reviews)
"Great stay in a nice location. We just stayed a night on the way up the Cape. It was just what we needed. Simple, clean, and good location."
United States
Jamie
The price is €142
includes taxes & fees
13 Jul - 14 Jul
Cape Cod Inn
Indoor pool

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.6 out of 10, Excellent, (98 reviews)
"Clean room staff was good hot tub was awesome and quiet place when we went"
United States
Jake
The price is €189
includes taxes & fees
12 Jul - 13 Jul
Courtyard Resort
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,540 reviews)
The price is €247
includes taxes & fees
9 Aug - 10 Aug
Bayside Resort Hotel
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,005 reviews)
"We loved to stay"
United States
Evelin
The price is €272
includes taxes & fees
2 Aug - 3 Aug
Hampton Inn & Suites Cape Cod-West Yarmouth
Free daily continental breakfast

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (1,008 reviews)
"Really nice room"
United States
Carl
The price is €179
includes taxes & fees
2 Aug - 3 Aug
Comfort Inn Hyannis - Cape Cod
Indoor pool, seasonal outdoor pool, pool loungers

Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod
2.0 star property
0.5 km from Main Street Hyannis
7.8 out of 10, Good, (1,007 reviews)
"It was nice place to stay"
United States
Celvin
The price is €129
includes taxes & fees
13 Jul - 14 Jul
Americas Best Value Inn & Suites Hyannis Cape Cod
Exterior

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,104 reviews)
"The location was very ideal nd central. Staff was helpful and the stay was affordable."
United States
Ronil
The price is €148
includes taxes & fees
13 Jul - 14 Jul
Cape Sands Inn
Reception

Hyannis Host Inn

Hyannis Host Inn
2.0 star property
1.6 km from Main Street Hyannis
7.8 out of 10, Good, (482 reviews)
"Stay was pleasant"
United States
Phyllis
The price is €120
includes taxes & fees
12 Jul - 13 Jul
Hyannis Host Inn
Exterior

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,004 reviews)
"Room was clean and spacious, we enjoy the outdoor pool and the hot tub, we had a great stay and would definitely come back"
United States
veronica
The price is €202
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Hyannis by IHG
Beach

Sunbird Cape Cod Resort

Sunbird Cape Cod Resort
2.5 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (575 reviews)
"Both pools were fantastic. Great breakfast. Air conditioner worked great. Friendly staff."
United States
Elizabeth
The price is €156
includes taxes & fees
14 Jul - 15 Jul
Sunbird Cape Cod Resort
Beach

Sunbird ANNEX Resort

Sunbird ANNEX Resort
2.0 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (865 reviews)
"Very clean ,great location, nice stuff!"
Canada
Tinka
The price is €171
includes taxes & fees
14 Jul - 15 Jul
Sunbird ANNEX Resort
Lobby

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.2 out of 10, Good, (1,017 reviews)
"Very friendly staff. Property was clean and a good value"
United States
brian
The price is €139
includes taxes & fees
12 Jul - 13 Jul
Hyannis Plaza Hotel
View from property

Ocean Street Inn on Hyannis Harbor

Ocean Street Inn on Hyannis Harbor
2.0 star property
0.4 km from Main Street Hyannis
7.0 out of 10, Good, (813 reviews)
"Close to being On the water with clean rooms. Lots of places to eat and the check in staff was awesome and plenty of parking"
United States
Greg
The price is €175
includes taxes & fees
13 Jul - 14 Jul
Ocean Street Inn on Hyannis Harbor
Lobby

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
2.0 star property
1.5 km from Main Street Hyannis
7.0 out of 10, Good, (1,008 reviews)
"This location is close to the ferry and"
United States
Gabriella
The price is €118
includes taxes & fees
12 Jul - 13 Jul
Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
Iron/ironing board, free WiFi, bed sheets

Relax Inn Cape Cod

Relax Inn Cape Cod
2.0 star property
1.4 km from Main Street Hyannis
6.4 out of 10, (786 reviews)
"We had an unexpected family emergency and the staff was very helpful and accommodating. Thankyou!"
United States
Jodi
The price is €119
includes taxes & fees
12 Jul - 13 Jul
Relax Inn Cape Cod
Seasonal outdoor pool

Econo Lodge West Yarmouth on Cape Cod

Econo Lodge West Yarmouth on Cape Cod
2.5 star property
1.5 km from Main Street Hyannis
6.2 out of 10, (516 reviews)
"Property needs to be updated especially tubs."
United States
Lisa
The price is €119
includes taxes & fees
12 Jul - 13 Jul
Econo Lodge West Yarmouth on Cape Cod
House

Water Access 5-bed 2-bath Retreat

Water Access 5-bed 2-bath Retreat
2.5 star property
0.6 km from Main Street Hyannis
The price is €1,060
includes taxes & fees
15 Jul - 16 Jul
Water Access 5-bed 2-bath Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Luxury King Room
Sea Street Inn
4.0 star property
9.8
Exceptional
46 reviews
View
Indoor pool, seasonal outdoor pool
Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
9.4
Exceptional
204 reviews
View
Exterior
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
8.8
Excellent
54 reviews
View
Marina
Cape Cod Inn
2.0 star property
8.6
Excellent
523 reviews
View
Indoor pool
Courtyard Resort
2.0 star property
8.6
Excellent
98 reviews
View

Top Main Street Hyannis Hotel Reviews

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

10/10 Excellent
"Everything was on point. Breakfast in morning and everything is close by. Plus, its affordable as well."
Vincent 2-night trip
Posted less than an hour ago
Comfort Inn Hyannis - Cape Cod

Hotels near other Main Street Hyannis attractions

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 199 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Heritage House Inn on Cape Cod, an Ascend Collection Hotel and Hyannis Harbor Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 199 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Cape Cod Maritime Museum and Whydah Pirate Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.