Hyannis Hotel Guide - Main Street Hyannis hotels in Hyannis, United States of America.

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Our top choices for Main Street Hyannis hotels

Hyannis Travel Inn

Hyannis Travel Inn
2.5 star property
0.2 km from Main Street Hyannis
9.6 out of 10, Exceptional, (1,002 reviews)
"Easy to get to...helpful, courteous check-in...it feels like the good ol' Cape Cod my wife knew back in the day. Friendly and grateful we chose Hyannis Travel Inn..."
United States
Carlo
The price is €97
includes taxes & fees
12 Apr - 13 Apr
Hyannis Travel Inn

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice view of Hyannis Harbor. Short drive to shopping and restaurants."
United States
Maureen
The price is €155
includes taxes & fees
14 Apr - 15 Apr
Anchor In Distinctive Waterfront Lodging

Cape Cod Harbor House Inn

Cape Cod Harbor House Inn
2.5 star property
0.4 km from Main Street Hyannis
9.2 out of 10, Wonderful, (309 reviews)
"Great location in downtown Hyannis. "
United States
Greg
The price is €97
includes taxes & fees
3 May - 4 May
Cape Cod Harbor House Inn

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45 reviews)
"The Sea Street Inn run by the exceptional chef Adrian far exceeded our expectations. The inn has an artistic flair and is serenely comfortable. What will keep us coming back is the four course breakfast prepared by Adrian each morning. If you love fine food and relaxed comfort the Sea Street Inn in Hyannis should be your next Cape Cod destination."
United States
Frank
The price is €269
includes taxes & fees
12 Apr - 13 Apr
Sea Street Inn

Cape Cod Inn

Cape Cod Inn
2.0 star property
0.2 km from Main Street Hyannis
8.8 out of 10, Excellent, (506 reviews)
"Excellent stay in this motel, located in Hyannis downtown. "
United States
Corinne
The price is €101
includes taxes & fees
21 Apr - 22 Apr
Cape Cod Inn

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
1.9 km from Main Street Hyannis
9.2 out of 10, Wonderful, (125 reviews)
"So clean and gorgeous rooms and property. Heated pool was amazing for early fall and the bonfires were so fun. Perfect location to get to West Yarmouth Favorites , and 4 minutes away from Hyannis Mainstreet. Already have our next trip booked"
United States
Olivia
The price is €122
includes taxes & fees
13 Apr - 14 Apr
Uncommoner Hotel by Reverie Boutique Collection

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (688 reviews)
"clean room. nice location "
United States
Tracey
The price is €131
includes taxes & fees
26 Apr - 27 Apr
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,548 reviews)
"Friendly and helpful staff. Breakfast is perfect to start your day. It's a quiet and beautiful place with a view of marshland and the bay. It's not far from the Cape Cod -Hyannis ferry to Nantucket and Martha’s Vineyard. "
United States
Noemi
The price is €127
includes taxes & fees
13 Apr - 14 Apr
Bayside Resort Hotel

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,000 reviews)
"Good location near Hyannis Port restaurants, clean, quiet."
United States
Tracy
The price is €131
includes taxes & fees
3 May - 4 May
Hampton Inn & Suites Cape Cod-West Yarmouth

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (72 reviews)
"This was my 4th time and I will continue staying here anytime I vacation in Hyannis. Staff is helpful with easy checkin and checkout. It’s clean, comfortable, and a very short walk to main st. which is so convenient. I really enjoy spending time in the indoor hot tub and pool "
United States
Karin
The price is €106
includes taxes & fees
12 Apr - 13 Apr
Courtyard Resort

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (496 reviews)
"Great place to stay in Hyannis. Friendly staff and clean."
United States
Alexis
The price is €140
includes taxes & fees
19 Apr - 20 Apr
Courtyard By Marriott Cape Cod Hyannis

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (20 reviews)
"Great staff. Really friendly and helpful. Room was spacious and clean. Close to Main Street. I would definitely stay again the next time we visit cape cod!"
Canada
MIKI
The price is €111
includes taxes & fees
3 May - 4 May
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (896 reviews)
"I was surprised with the immaculate and modern updates to the Fairfield Inn. Lovely staff and very comfortable accommodations. Location was perfect for my business meetings with several clients in neighboring hotels. The BEST find was it was located right next door to Barnes & Noble in the Cape Cod Mall"
United States
Barbara
The price is €140
includes taxes & fees
22 Apr - 23 Apr
Doubletree by Hilton Cape Cod - Hyannis

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,035 reviews)
"Reasonable price for a place to stay in Cape Cod with a comfortable room and amenities such as a pool & hot tub. Located along the main drag in Yarmouth and not far from Hyannis."
United States
Philip
The price is €63
includes taxes & fees
14 Apr - 15 Apr
Cape Sands Inn

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1,002 reviews)
"Perfect hotel to stay in. It’s comfortable the staff is very friendly and very knowledgeable about all aspects. In just min from main St and all the storefronts and other areas of the town of Hyannis. "
United States
Jarred
The price is €111
includes taxes & fees
27 Apr - 28 Apr
Comfort Inn Hyannis - Cape Cod

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,001 reviews)
"Very cute hotel directly across from the ferry. You can keep you car in the parking lot there while you take the ferry across. Great breakfast place across the street! "
United States
Shannon
The price is €145
includes taxes & fees
12 Apr - 13 Apr
Hyannis Harbor Hotel

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,001 reviews)
"Great option for being in Hyannis. I had a suite that was actually a duplex. The dining options were great & the amenities such as the indoor pool. "
United States
Laure-Ann
The price is €124
includes taxes & fees
19 Apr - 20 Apr
Holiday Inn Hyannis by IHG

Hyannis Host Inn

Hyannis Host Inn
2.0 star property
1.6 km from Main Street Hyannis
7.8 out of 10, Good, (457 reviews)
"The room was big and the king size bed was comfy. It’s a simple place to stay for a great price. Great for a visit to Hyannis. "
United States
Albert
The price is €97
includes taxes & fees
12 Apr - 13 Apr
Hyannis Host Inn

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
1.8 km from Main Street Hyannis
7.8 out of 10, Good, (196 reviews)
"The Sea Breeze was an economical stay in the Cape. Other options were super expensive so the Sea Breeze was great for our 3 night stay. The property is a little older but everything was clean and functional. The property is a 4 minute walk to the beach, 1 mile from the Kennedy Compound and 2.5 miles from Main Street. Boston is just 1.5 hours, Provincetown at the end of the cape is just an hour drive. We enjoyed Kate's Ice Cream, breakfast at the Daily Paper and supper ate Pizza Borbone...
United States
Phillip
The price is €87
includes taxes & fees
14 Apr - 15 Apr
Sea Breeze Inn

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (1,003 reviews)
"We went to the Hyannis Music Tent and they were in walking distance. The area had great shops and restaurant."
United States
Winifred
The price is €122
includes taxes & fees
29 Apr - 30 Apr
Hyannis Plaza Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Hyannis Travel Inn
2.5 star property
9.6
Exceptional
1,002 reviews
View
Terrace/patio
Anchor In Distinctive Waterfront Lodging
3.0 star property
9.4
Exceptional
1,002 reviews
View
Exterior
Cape Cod Harbor House Inn
2.5 star property
9.2
Wonderful
309 reviews
View
Luxury King Room
Sea Street Inn
4.0 star property
9.8
Exceptional
45 reviews
View
Marina
Cape Cod Inn
2.0 star property
8.8
Excellent
506 reviews
View

Top Main Street Hyannis Hotel Reviews

Hotels near other Main Street Hyannis attractions

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 186 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Comfort Inn Hyannis - Cape Cod and Anchor In Distinctive Waterfront Lodging.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 186 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Toad Hall Classic Sports Car Museum and Whydah Pirate Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and West Parish Meetinghouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Dennis Pond Conservation Area and Veterans Memorial Park are peaceful spots to stop and take in some fresh air.