Hyannis Hotel Guide - Main Street Hyannis hotels in Hyannis, United States of America.

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Check prices for these dates

Tonight
7 Jan - 8 Jan
Tomorrow
8 Jan - 9 Jan
This weekend
9 Jan - 11 Jan
Next weekend
16 Jan - 18 Jan

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Our top choices for Main Street Hyannis hotels

Terrace/patio
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1005)
"Staff member Sandy very congenial when we checked in. Laid back atmosphere (early December). Will consider for future Hyannis stay."
United States
Lawrence
The price is €156
includes taxes & fees
8 Jan - 9 Jan
Anchor In Distinctive Waterfront Lodging
Luxury King Room
Sea Street Inn

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45)
"Adrian was an awesome host. Comfortable bed, safe area to walk, beautiful surroundings."
United States
Jori
The price is €220
includes taxes & fees
8 Jan - 9 Jan
Sea Street Inn
Indoor pool, seasonal outdoor pool
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (100)
"Clean, nice staff, good amenities, central location"
United States
Malbis
The price is €136
includes taxes & fees
9 Jan - 10 Jan
Uncommoner Hotel by Reverie Boutique Collection
Indoor pool, seasonal outdoor pool
The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
2.1 km from Main Street Hyannis
9.2 out of 10, Wonderful, (244)
"The staff are amazing! Love the amenities - the pool, recreation center, activities for the kids such as windchime arts and crafts. The arcade is always a hit. The Loft makes it so easy to not have to stress about a place to go to for dinner. The Cove is a great place for everyone! "
United States
Lauren
The price is €126
includes taxes & fees
8 Jan - 9 Jan
The Cove at Yarmouth by Westgate Resorts
Indoor pool
Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (490)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is €124
includes taxes & fees
29 Jan - 30 Jan
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Bayside Resort Hotel

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1534)
"All the resort and staff was great!"
United States
Sandra
The price is €107
includes taxes & fees
8 Jan - 9 Jan
Bayside Resort Hotel
Indoor pool
Courtyard Resort

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (50)
"Clean and inexpensive"
United States
Robert
The price is €106
includes taxes & fees
8 Jan - 9 Jan
Courtyard Resort
Exterior
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
1 km from Main Street Hyannis
8.4 out of 10, Very good, (882)
"Clean hotel, kind staff, the kids loved the warm indoor pool since it’s winter. All was good. "
United States
Tania
The price is €118
includes taxes & fees
7 Feb - 8 Feb
Doubletree by Hilton Cape Cod - Hyannis
Free daily continental breakfast
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1000)
"Nice hotel had a perfect stay"
United States
David
The price is €97
includes taxes & fees
29 Jan - 30 Jan
Comfort Inn Hyannis - Cape Cod
Front of property
Hyannis Harbor Hotel

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1005)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is €155
includes taxes & fees
25 Jan - 26 Jan
Hyannis Harbor Hotel
Exterior
Cape Sands Inn

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1015)
"Clean room courteous staff and easy check in "
United States
Linda
The price is €98
includes taxes & fees
8 Jan - 9 Jan
Cape Sands Inn
Exterior
Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (982)
"Nice place"
United States
Linda
The price is €111
includes taxes & fees
15 Jan - 16 Jan
Holiday Inn Hyannis by IHG
Lobby
Hyannis Plaza Hotel

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (984)
"The best staff abd it was clean and beautiful "
United States
Heather
The price is €90
includes taxes & fees
7 Feb - 8 Feb
Hyannis Plaza Hotel
Family House, Private Bathroom, Pool View | Lounge
Sal's Place

Sal's Place

Sal's Place
2.0 star property
2.5 km from Main Street Hyannis
The price is €493
includes taxes & fees
20 Jan - 21 Jan
Sal's Place
Front of property
The Village Inn Cape Cod

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (223)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is €181
includes taxes & fees
8 Jan - 9 Jan
The Village Inn Cape Cod
Outdoor pool, pool umbrellas, pool loungers
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
3.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (424)
"Kids animals show ,clean room ,great staff, food great ,amenities 🙏❤️"
United States
Rosa Xavier
Margaritaville Resort Cape Cod
Property grounds
The Escape Inn

The Escape Inn

The Escape Inn
2.5 star property
7.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (661)
"Great place"
United States
Karim
The price is €78
includes taxes & fees
8 Jan - 9 Jan
The Escape Inn
Exterior
Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
3.7 km from Main Street Hyannis
8.0 out of 10, Very good, (1007)
"Clean room | Breakfast | Bar | Staff"
United States
Daniel
The price is €95
includes taxes & fees
19 Jan - 20 Jan
Aiden by Best Western Cape Cod - West Yarmouth
Indoor pool, open 8:00 AM to 10:00 PM, pool loungers
The Mariner Resort Cape Cod by The Red Collection

The Mariner Resort Cape Cod by The Red Collection

The Mariner Resort Cape Cod by The Red Collection
3.0 star property
4.3 km from Main Street Hyannis
8.0 out of 10, Very good, (442)
"yes, clean room, staff are great, amenities are fine."
United States
James and Lisa
The price is €81
includes taxes & fees
11 Jan - 12 Jan
The Mariner Resort Cape Cod by The Red Collection
Front of property
Ambassador Inn & Suites

Ambassador Inn & Suites

Ambassador Inn & Suites
3.0 star property
8.2 km from Main Street Hyannis
8.6 out of 10, Excellent, (630)
"I love staying here. "
United States
Jacqueline
Ambassador Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Hyannis Hotel Reviews

Bayside Resort Hotel

Bayside Resort Hotel

10/10 Excellent
"Amazing!"
Erika 1-night trip
Posted 2 days ago
Bayside Resort Hotel

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
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Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the beautiful beaches in this family-friendly area or visit its seafood restaurants.
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Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 183 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Courtyard Resort is one of the top choices for your stay based on our traveller data, and this hotel offers an indoor pool and free parking. Other good options within a short distance include Hyannis Travel Inn and Comfort Inn Hyannis - Cape Cod.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 183 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Sandy Neck Lighthouse and West Parish Meetinghouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.