A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.

Hyannis Hotel Guide - Main Street Hyannis hotels in Hyannis, United States of America.

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Check prices for these dates

Tonight
9 Oct - 10 Oct
Tomorrow
10 Oct - 11 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

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Our top choices for Main Street Hyannis hotels

A multi-story hotel with balconies, a flat roof, and a clear sky.
An indoor swimming pool with clear water, surrounded by black chairs and tables.
A reception area with a counter, a seated area with a lamp, and framed pictures on the wall.
A hotel room with two beds, a desk, a chair, a lamp, and a nightstand with a phone and a small table.

1. Hyannis Travel Inn

Hyannis Travel Inn
0.2 km from Main Street Hyannis
United States
David J
€101
includes taxes & fees
13 Oct - 14 Oct
Hyannis Travel Inn
Two green chairs, a white table with a black mug, a white tote bag, and a wicker bike basket with a handle.
A row of white bicycles with brown seats and wicker baskets, parked in front of a white building with black railings and large windows.
A modern indoor dining area with a wooden table, chairs, and a decorative wall with string lights.
A poolside area with a wooden pergola, green seating, and a sign reading "LE JARDIN BLEU".

2. Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
1.9 km from Main Street Hyannis
€110
includes taxes & fees
2 Nov - 3 Nov
Uncommoner Hotel by Reverie Boutique Collection
A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.
A marina with multiple boats docked, surrounded by residential houses and greenery.
A hotel with a pool area, outdoor seating, and a flag.
A row of wicker chairs with cushions, a map on the wall, and a view of the outside through a window.

3. Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
0.6 km from Main Street Hyannis
United States
kathy
€172
includes taxes & fees
2 Nov - 3 Nov
Anchor In Distinctive Waterfront Lodging
A pool area with lounge chairs and flags.
A beachside seating area with Adirondack chairs arranged around a stone fire pit.
A modern building with a sloped roof, large windows, and a covered entrance area with seating.
A restaurant interior with tables and chairs, decorative lanterns, and potted plants.

4. The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
2.1 km from Main Street Hyannis
United States
Kim
€132
includes taxes & fees
2 Nov - 3 Nov
The Cove at Yarmouth by Westgate Resorts
A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.
A hallway with a sign reading 'ASCEND COLLECTION,' a wooden planter with plants, and a reflective floor.
A living room with a sofa, coffee table, and patterned chair. There are two wall-mounted ship wheels and a framed picture on the wall.
An indoor swimming pool with lounge chairs, a stone wall, and a mezzanine level.

5. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
0.3 km from Main Street Hyannis
United States
Berita
€129
includes taxes & fees
2 Nov - 3 Nov
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
A modern conference room with a long table, chairs, a flat-screen TV, and pendant lighting.
A hotel room with a bed, a TV, a sofa, a lamp, and a chair.
A modern reception area with a desk, chairs, a fireplace, and a decorative plant.
A Fairfield by Marriott hotel with a large sign, a covered entrance, and a building with a tower.

6. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
2.3 km from Main Street Hyannis
United States
Joyce
€129
includes taxes & fees
26 Oct - 27 Oct
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
An indoor swimming pool with a high ceiling and large windows.
A modern bar area with a curved wooden counter, multiple stools, and a display case with beverages.
A hotel reception area with a digital display showing today's weather and this week's forecast.
View from property

7. Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
1.7 km from Main Street Hyannis
United States
SHREYASI
€128
includes taxes & fees
25 Oct - 26 Oct
Courtyard By Marriott Cape Cod Hyannis
An outdoor patio with wicker furniture, a fire pit, and umbrellas.
A breakfast bar with waffle makers, a fruit bowl, and a coffee station.
A reception area with a sign reading "Welcome to the Patriot State" and a counter with a "Hilton" sign.
An indoor swimming pool with clear signage, lounge chairs, and a tiled floor.

8. Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
1.7 km from Main Street Hyannis
United States
Carmen E
€112
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn & Suites Cape Cod-West Yarmouth
An indoor swimming pool with a wooden ceiling, potted plants, and lounge chairs.
A hotel room with a bed, a chair, a table with two glasses of wine, a lamp, and a window with a view of a lake.
A two-story building with a prominent tower, large windows, and a well-lit entrance.
A beach scene with a directional signpost and beach chairs.

9. Bayside Resort Hotel

Bayside Resort Hotel
2.3 km from Main Street Hyannis
United States
Lynn
€101
includes taxes & fees
8 Nov - 9 Nov
Bayside Resort Hotel
An indoor swimming pool with a brick wall, a white table with chairs, and a large window.
A compact hotel room with a kitchenette, a bed, a dining area, and a view through a large window.
A multi-story hotel with a well-maintained lawn, outdoor seating area with chairs, and a wooden deck.
A reception area with a reception desk, a clock, a fire alarm, and a sign for the courtyard resort.

10. Courtyard Resort

Courtyard Resort
0.3 km from Main Street Hyannis
United States
Blagoy
€143
includes taxes & fees
13 Oct - 14 Oct
Courtyard Resort
An outdoor seating area with wooden furniture and a fire pit, surrounded by trees and a gravel path.
A lobby with a wooden floor, a reception desk, a large window, and a ceiling fan.
A row of white buildings with balconies, outdoor seating, and flower beds.
A neatly made bed with white linens, a painting of a sailboat on the wall, and a door leading to a balcony.

11. Cape Sands Inn

Cape Sands Inn
1.9 km from Main Street Hyannis
United States
Jerome
€74
includes taxes & fees
15 Oct - 16 Oct
Cape Sands Inn
An outdoor patio with round tables and chairs, a fire pit, and a covered seating area with string lights.
A large indoor swimming pool with multiple lanes, surrounded by rows of chairs and a high ceiling with large windows.
A DoubleTree hotel with a brick facade and a large sign.
A modern lounge area with a stone wall, a flat-screen TV, and comfortable seating.

12. Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
0.9 km from Main Street Hyannis
Canada
Tammie
€128
includes taxes & fees
8 Nov - 9 Nov
Doubletree by Hilton Cape Cod - Hyannis
A gym with various cardio and strength training equipment, including treadmills, elliptical machines, and weight machines.
A swimming pool with chairs and umbrellas, surrounded by a fence and greenery.
A Holiday Inn hotel entrance with a covered walkway, a parking lot, and a landscaped area with a water feature.
A hotel room with two beds, a desk with a computer, a chair, and a window with curtains.

13. Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
2.9 km from Main Street Hyannis
United States
Alexander
€130
includes taxes & fees
2 Nov - 3 Nov
Holiday Inn Hyannis by IHG
A long dining table with chairs, a kitchen area, and a large window.
An indoor swimming pool with clear blue water, tiled walls, and a ceiling painted in blue.
A hotel room with a bed, a desk with a flat-screen TV, a coffee maker, a microwave, a vacuum cleaner, and a sliding door to a balcony.
A Comfort Inn hotel with a modern facade, large glass windows, and a clear sky.

14. Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
0.3 km from Main Street Hyannis
United States
catherine
€115
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn Hyannis - Cape Cod
A two-story hotel with a curved facade, a balcony, and a sign indicating the lobby.
A waterfront hotel with a view of the marina and boats.
A modern living room with two sofas, a coffee table, and a stone wall with a fireplace.
A resort pool area with multiple lounge chairs and umbrellas, a hot tub, and a large building in the background.

15. Hyannis Harbor Hotel

Hyannis Harbor Hotel
0.6 km from Main Street Hyannis
United States
Jayne
€154
includes taxes & fees
25 Oct - 26 Oct
Hyannis Harbor Hotel
A beach with clear skies and gentle waves.
A grassy area with blue Adirondack chairs arranged around a central fire pit. In the background, there are two buildings with a playground structure.
A fire pit with chairs arranged around it, set on sandy ground with a wooden fence and foliage in the background.
A reception area with a wooden counter, a blue accent wall, and striped armchairs.

16. Sunbird Cape Cod Resort

Sunbird Cape Cod Resort
2.3 km from Main Street Hyannis
€98
includes taxes & fees
12 Oct - 13 Oct
Sunbird Cape Cod Resort
An indoor swimming pool with a covered area, poolside chairs, and a table.
A hotel room with a large bed, two bedside lamps, a nightstand, a framed picture on the wall, and a curtain.
A spacious living area with a large TV, comfortable seating, and a view of the outside.
A spacious living area with a kitchen, a coffee machine, a television, and a magazine rack.

17. Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod
0.5 km from Main Street Hyannis
United States
Linda
€91
includes taxes & fees
11 Oct - 12 Oct
Americas Best Value Inn & Suites Hyannis Cape Cod
A beach with clear skies and gentle waves.
A reception area with a wooden counter, a blue accent wall, and striped armchairs.
A swimming pool with clear blue water, surrounded by a tiled deck and a building with a green roof in the background.
A sand sculpture of a sun with sunglasses and the text "Fun in the Sun" on a beach.

18. Sunbird ANNEX Resort

Sunbird ANNEX Resort
2.3 km from Main Street Hyannis
United States
Evroy
€90
includes taxes & fees
12 Oct - 13 Oct
Sunbird ANNEX Resort
A modern living room with a sofa, coffee table, and kitchen area with appliances.
A hotel room with a desk, a television, a microwave, and a window with curtains.
A building with a covered entrance, a parking lot, and a tree with pink blossoms.
A bedroom with a bed, a dresser, a TV, a window with blinds, and an air conditioner.

19. Hyannis Host Inn

Hyannis Host Inn
1.6 km from Main Street Hyannis
United States
Keith
€155
includes taxes & fees
10 Oct - 11 Oct
Hyannis Host Inn
A house with a brick exterior and a covered patio area.
A bathroom with a bathtub, a shower, and a toilet. There are towels hanging on the wall.
A two-story wooden house with a white picket fence, an American flag, and a sign indicating a business on the ground floor.
A four-poster bed with a footboard, a bedside table with a lamp, a wooden bench, and a dresser with a mirror.

20. Sea Breeze Inn

Sea Breeze Inn
1.8 km from Main Street Hyannis
United States
Rita
€81
includes taxes & fees
4 Nov - 5 Nov
Sea Breeze Inn
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A multi-story hotel with balconies, a flat roof, and a clear sky.
Hyannis Travel Inn
9.6
Exceptional
1,008 reviews
View
Two green chairs, a white table with a black mug, a white tote bag, and a wicker bike basket with a handle.
Uncommoner Hotel by Reverie Boutique Collection
9.2
Wonderful
365 reviews
View
A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.
Anchor In Distinctive Waterfront Lodging
9.4
Exceptional
1,000 reviews
View
A pool area with lounge chairs and flags.
The Cove at Yarmouth by Westgate Resorts
9.2
Wonderful
269 reviews
View
A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
9.0
Wonderful
174 reviews
View

Hotels recommended for families near Main Street Hyannis

A multi-story hotel with balconies, a flat roof, and a clear sky.
An indoor swimming pool with clear water, surrounded by black chairs and tables.
A reception area with a counter, a seated area with a lamp, and framed pictures on the wall.
A hotel room with two beds, a desk, a chair, a lamp, and a nightstand with a phone and a small table.

Hyannis Travel Inn

Hyannis Travel Inn
Hyannis
€101
includes taxes & fees
13 Oct - 14 Oct
Hyannis Travel Inn
A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.
A hallway with a sign reading 'ASCEND COLLECTION,' a wooden planter with plants, and a reflective floor.
A living room with a sofa, coffee table, and patterned chair. There are two wall-mounted ship wheels and a framed picture on the wall.
An indoor swimming pool with lounge chairs, a stone wall, and a mezzanine level.

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Hyannis
€129
includes taxes & fees
2 Nov - 3 Nov
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
An indoor swimming pool with a brick wall, a white table with chairs, and a large window.
A compact hotel room with a kitchenette, a bed, a dining area, and a view through a large window.
A multi-story hotel with a well-maintained lawn, outdoor seating area with chairs, and a wooden deck.
A reception area with a reception desk, a clock, a fire alarm, and a sign for the courtyard resort.

Courtyard Resort

Courtyard Resort
Hyannis
€143
includes taxes & fees
13 Oct - 14 Oct
Courtyard Resort
A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.
A marina with multiple boats docked, surrounded by residential houses and greenery.
A hotel with a pool area, outdoor seating, and a flag.
A row of wicker chairs with cushions, a map on the wall, and a view of the outside through a window.

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
Hyannis
€172
includes taxes & fees
2 Nov - 3 Nov
Anchor In Distinctive Waterfront Lodging
A covered outdoor seating area with wicker furniture and a glass-top table.
A compact kitchen with a microwave, a window, a sink, and a radiator.
A restaurant with wooden tables and chairs, a counter with a cash register, and large windows offering a view of the outside.
A hotel room with two beds, a red armchair, and a window with curtains.

Cape Cod Harbor House Inn

Cape Cod Harbor House Inn
Hyannis
€121
includes taxes & fees
13 Oct - 14 Oct
Cape Cod Harbor House Inn
A beach with clear skies and gentle waves.
A reception area with a wooden counter, a blue accent wall, and striped armchairs.
A swimming pool with clear blue water, surrounded by a tiled deck and a building with a green roof in the background.
A sand sculpture of a sun with sunglasses and the text "Fun in the Sun" on a beach.

Sunbird ANNEX Resort

Sunbird ANNEX Resort
West Yarmouth
€90
includes taxes & fees
12 Oct - 13 Oct
Sunbird ANNEX Resort
A long dining table with chairs, a kitchen area, and a large window.
An indoor swimming pool with clear blue water, tiled walls, and a ceiling painted in blue.
A hotel room with a bed, a desk with a flat-screen TV, a coffee maker, a microwave, a vacuum cleaner, and a sliding door to a balcony.
A Comfort Inn hotel with a modern facade, large glass windows, and a clear sky.

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
Hyannis
€115
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn Hyannis - Cape Cod
An indoor swimming pool with a covered area, poolside chairs, and a table.
A hotel room with a large bed, two bedside lamps, a nightstand, a framed picture on the wall, and a curtain.
A spacious living area with a large TV, comfortable seating, and a view of the outside.
A spacious living area with a kitchen, a coffee machine, a television, and a magazine rack.

Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod
Hyannis
€91
includes taxes & fees
11 Oct - 12 Oct
Americas Best Value Inn & Suites Hyannis Cape Cod

Top Main Street Hyannis Hotel Reviews

Hyannis Harbor Hotel

Hyannis Harbor Hotel

10/10 Excellent
"Wonderful place to stay and very convenient to the ferry and nearby restaurants/bars! Loved it."
Susan 1-night trip
Posted 9 hours ago
Hyannis Harbor Hotel
SeaCoast Inn

SeaCoast Inn

10/10 Excellent
"Very nice location to harbor and to main street hyannis. The room had nice decor and kitchenette was a great extra. The staff was super helpful and friendly."
Terri 2-night trip
Posted 12 hours ago
SeaCoast Inn
Hyannis Travel Inn

Hyannis Travel Inn

10/10 Excellent
"Location was fantastic! It’s centrally located and walking distance to many restaurants and taverns in Hyannis. Everyone at the front desk was friendly. Room was spacious. Breakfast was adequate."
Crystal 1-night trip
Posted 14 hours ago
Hyannis Travel Inn
Courtyard Resort

Courtyard Resort

10/10 Excellent
"Loved that the door opened fri fresh air. Bathroom was super clean. Kitchen was well equipped. Everything was great"
Jenna 2-night trip
Posted 16 hours ago
Courtyard Resort
Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod

10/10 Excellent
"This place is not bad. The location is great and for the price you can't beat it. Best water pressure I've ever had at a hotel."
Emily 4-night trip
Posted 18 hours ago
Americas Best Value Inn & Suites Hyannis Cape Cod
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

8/10 Good
"Solid accessible-type room. Ample, good quality continental breakfast. Again enjoyed convenient access to the Hyannis Transportation Center across the street. Perfect temperature room, without having to constantly fiddle with controls. The only deficit was limited sports on big screen TV offerings."
Gregory 1-night trip
Posted 19 hours ago
Comfort Inn Hyannis - Cape Cod
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

10/10 Excellent
"Even with my late arrival the front desk manager was so kind and welcoming. I found this hotel to be an excellent place for a stay in this area. It was recently renovated and all was fresh and clean."
Ernestina 1-night trip
Posted 2 days ago
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Hyannis Plaza Hotel

Hyannis Plaza Hotel

10/10 Excellent
"Very happy"
Sharon 1-night trip
Posted 2 days ago
Hyannis Plaza Hotel
Cape Cod Harbor House Inn

Cape Cod Harbor House Inn

10/10 Excellent
"Room was clean, staff particularly helpful, parking on site, convenient to restaurants , beach , and stores. Would definitely stay here again."
Olivia 2-night trip
Posted 4 days ago
Cape Cod Harbor House Inn

Other attractions near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
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The Cape Cod Maritime Museum with a green sign, a white entrance, and flower planters.

Cape Cod Maritime Museum

9.0/10 (16 reviews)
You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants.
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A white church with a steeple and a sign for Saint Francis Xavier Sunday masses.

St. Francis Xavier Church

8.6/10 (58 reviews)
After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area.
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A memorial plaque with a bust of John F. Kennedy surrounded by a stone wall.

John F. Kennedy Memorial

9.0/10 (262 reviews)
Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.
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Hyannis Armory

Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area.
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Hyannis Youth & Community Center

8.2/10 (22 reviews)
You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area.
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Zion Union Heritage Museum

6.0/10 (1 review)
You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants.
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Commotion Charters

6.0/10 (3 reviews)
Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area.
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Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 197 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Hyannis Harbor Hotel and Hyannis Plaza Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 197 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Centerville Historical Museum and Edward Gorey House feature captivating exhibits. Hyannis Harbor, Sandy Neck Lighthouse and West Parish Meetinghouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.