Main Street Hyannis

A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.
Street signs for Waterfront, Fishing/Tour Boats, and Street.
A street with ice cream shops and a skate shop.
A red brick building with a white arched entrance, a large clock, and a window with an air conditioning unit.
A directional sign with 'Waterfront' and 'Fishing/Tour Boats' pointing to the left.

Things to do

Cape Cod and Provincetown Scenic Self-Guided Driving Audio Tour

Cape Cod & Provincetown: Self-Guided Drive & Walk Audio Tour

€22
per traveller
Cape Cod & Provincetown: Self-Guided Drive & Walk Audio Tour
Massachusetts Self-Guided Audio Tour Bundle: 10+ Tours

Massachusetts Self-Guided Audio Tour Bundle: 10+ Tours

€43
per adult
Massachusetts Self-Guided Audio Tour Bundle: 10+ Tours
See all activities in Hyannis
Price found within the past 48 hours. Click for updated prices.
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

3 out of 5
Price was €4,928, price is now €4,648 per person
€4,648
per person
5 Oct - 12 Oct
found 1 day ago
Return flight included
London (LON) to Hyannis (HYA)
9.4/10 Exceptional! (1,006 reviews)
Old , run down. Pool shut during our stay. Overall , needs a massive renovation.

Reviewed on 22 Aug 2026

Wequassett Resort and Golf Club

Wequassett Resort and Golf Club

5 out of 5
Price was €9,851, price is now €8,571 per person
€8,571
per person
5 Oct - 12 Oct
found 22 hours ago
Return flight included
London (LON) to Hyannis (HYA)
9.4/10 Exceptional! (267 reviews)

Chapter House

Chapter House

3.5 out of 5
Price was €5,165, price is now €4,809 per person
€4,809
per person
5 Oct - 12 Oct
found 22 hours ago
Return flight included
London (LON) to Hyannis (HYA)
9.2/10 Wonderful! (181 reviews)
A beautiful inn and lovely gardens and deck to enjoy. A bar and on some nights live music makes it even better.

Reviewed on 21 Aug 2026

Stay near popular Main Street Hyannis attractions

Main Street Hyannis

After visiting Main Street Hyannis, make a plan to see the other sights and activities in Hyannis. Visit the shops and top-notch restaurants in this walkable area.
See properties

Top Hotel Deals

Hyannis Harbor Hotel

Hyannis Harbor Hotel

3.5 out of 5
213 Ocean St Hyannis MA
Hyannis Harbor Hotel
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

4 out of 5
1225 Iyannough Rd Hyannis MA
Margaritaville Resort Cape Cod
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

4 out of 5
135 Route 28 West Yarmouth MA
Uncommoner Hotel by Reverie Boutique Collection
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

2.5 out of 5
540 Old Colony Rd Hyannis MA
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

2.5 out of 5
259 Main Street Hyannis MA
Comfort Inn Hyannis - Cape Cod
Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod

2 out of 5
206 Main St Hyannis MA
Americas Best Value Inn & Suites Hyannis Cape Cod
Hyannis Travel Inn

Hyannis Travel Inn

2.5 out of 5
18 North St Hyannis MA
Hyannis Travel Inn
Bayside Resort Hotel

Bayside Resort Hotel

3 out of 5
225 Route 28 West Yarmouth MA
Bayside Resort Hotel
Hyannis Plaza Hotel

Hyannis Plaza Hotel

2.5 out of 5
662 Main Street Hyannis MA
Hyannis Plaza Hotel
See all 3,737 properties in Main Street Hyannis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.