Hannibal Hotel Guide - Mark Twain Boyhood Home and Museum hotels in Hannibal, United States of America.

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Tonight
28 Dec - 29 Dec
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29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

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Our top choices for Mark Twain Boyhood Home and Museum hotels

55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
0.2 km from Mark Twain Boyhood Home and Museum
9.4 out of 10, Exceptional, (165)
"Great place to stay!"
United States
Sandy
The price is €186
includes taxes & fees
29 Dec - 30 Dec
Riverside Inn Hannibal
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Best Western On The River

Best Western On The River

Best Western On The River
2.5 star property
< 0.1 km from Mark Twain Boyhood Home and Museum
8.6 out of 10, Excellent, (1001)
"Great stay! Clean and cozy!!"
United States
Courtney
The price is €100
includes taxes & fees
29 Dec - 30 Dec
Best Western On The River
Lobby sitting area
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
2.9 km from Mark Twain Boyhood Home and Museum
7.4 out of 10, Good, (1001)
"Very clean rooms and staff is very friendly "
United States
Sherrie
The price is €57
includes taxes & fees
14 Jan - 15 Jan 2026
Motel 6 Hannibal, MO
Exterior
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
3 km from Mark Twain Boyhood Home and Museum
7.2 out of 10, Good, (1000)
"My stay was excellent staff very friendly and breakfast was always great "
United States
Sherrie
The price is €68
includes taxes & fees
26 Jan - 27 Jan 2026
Super 8 by Wyndham Hannibal
Deluxe Room
Lighthouse Inn & Suites

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
0.6 km from Mark Twain Boyhood Home and Museum
8.8 out of 10, Excellent, (24)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is €165
includes taxes & fees
29 Dec - 30 Dec
Lighthouse Inn & Suites
Front of property
Garden House Bed and Breakfast

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
0.3 km from Mark Twain Boyhood Home and Museum
8.6 out of 10, Excellent, (38)
"Overall stay was great and the host chris is great aswell nothing bad to say about any aspect of our stay!"
United States
Josh
The price is €105
includes taxes & fees
3 Jan - 4 Jan 2026
Garden House Bed and Breakfast
Exterior
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
6.6 km from Mark Twain Boyhood Home and Museum
9.6 out of 10, Exceptional, (1006)
"Very personable staff, easy check in"
United States
Cherie
The price is €97
includes taxes & fees
25 Jan - 26 Jan 2026
Sleep Inn & Suites Hannibal West
Lobby
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
6.4 km from Mark Twain Boyhood Home and Museum
8.0 out of 10, Very good, (1002)
"Very friendly staff. "
United States
Lawrence
The price is €69
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn & Suites Hannibal West
Indoor pool, pool loungers
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
4.8 km from Mark Twain Boyhood Home and Museum
7.6 out of 10, Good, (662)
"Below average facility. Needs some upgrades and could use a good cleaning. Staff was helpful."
United States
JACQUI
The price is €77
includes taxes & fees
3 Jan - 4 Jan 2026
Comfort Inn & Suites - Hannibal
Room, 2 Queen Beds, Non Smoking
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
4.9 km from Mark Twain Boyhood Home and Museum
7.4 out of 10, Good, (218)
"Left before breakfast great cup of coffee"
United States
David
The price is €66
includes taxes & fees
16 Jan - 17 Jan 2026
Days Inn by Wyndham Hannibal
Lobby sitting area
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
5 km from Mark Twain Boyhood Home and Museum
7.2 out of 10, Good, (153)
"The gentleman at the front desk was extremely nice and did everything to make my stay wonderful. The breakfast was awesome. The pool was sooo nice. The exercise room was great. I cannot say anything bad about this hotel. This was the first time I stayed here and I will be coming back every three months.!"
United States
Shawn
The price is €57
includes taxes & fees
30 Dec - 31 Dec
Howard Johnson BY Wyndham Hannibal
Desk, laptop workspace, iron/ironing board, free WiFi
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
5 km from Mark Twain Boyhood Home and Museum
6.4 out of 10, (737)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is €57
includes taxes & fees
30 Dec - 31 Dec
Baymont by Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mark Twain Boyhood Home and Museum Hotel Reviews

The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown

10/10 Excellent
"Our stay at the John Sydney house was wonderful. It’s a historic building with charm and I’m glad we chose this home which supports the renovations of other houses in the area. Modern appliances, comfy beds, and pet friendly."
Branda 6-night trip
Posted 2 days ago
The John Sydney House - Family and Pet Friendly Historic Home Downtown

Hotels near other Mark Twain Boyhood Home and Museum attractions

Mark Twain Memorial Lighthouse

4.3/5 (93 reviews)
You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this walkable area, you can savour the top-notch restaurants.
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Planters Barn Theater

Get tickets for a show at Planters Barn Theater, a popular theatre in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.
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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?
Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 39 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Mark Twain Boyhood Home and Museum?
Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Garden House Bed and Breakfast.
How many hotels will I find near Mark Twain Boyhood Home and Museum?
Expedia has 39 hotels and other accommodation options within a mile from Mark Twain Boyhood Home and Museum.
If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?
Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Mark Twain Boyhood Home and Museum.
What can I see and do near Mark Twain Boyhood Home and Museum?
You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion and Mark Twain Cave and Cameron Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Planters Barn Theater and Bluff City Theater.