A person wearing a straw hat and red bikini, standing on a beach with waves and a rocky cliff in the background.

Megalochori Hotel Guide - Luxury Hotels in Megalochori, Santorini

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Check availability on Megalochori Luxury Hotels

Tonight
4 Oct - 5 Oct
Tomorrow
5 Oct - 6 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Megalochori luxury hotels

A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea and distant islands.
A beachside lounge with a view of the sea and islands.
A modern bedroom with a large window, a bed, a chair, and a TV.
An underground restaurant with stone walls and vaulted ceilings, featuring tables set for dining with candles and wine glasses.

1. Vedema, a Luxury Collection Resort, Santorini

Vedema, a Luxury Collection Resort, Santorini
Santorini
  • Santorini beachfront luxury with private shore access, full-service spa, and three restaurants creates an indulgent Mediterranean retreat.
€321
includes taxes & fees
17 Oct - 18 Oct
Vedema, a Luxury Collection Resort, Santorini
A modern pool area with lounge chairs, a bar, and a staircase leading to upper levels.
A modern bedroom with a large bed, a wooden accent wall, a large window with a view, and a small bedside table with a vase.
A room with a large sliding door leading to a balcony, a round table with a bowl and a vase, and a chair.
A spa room with a hot tub, arched alcoves, and a view of the cityscape.

2. Enarma Suites & Spa Wellness Retreat

Enarma Suites & Spa Wellness Retreat
Santorini
  • Santorini wellness retreat pampers guests with Mediterranean dining, poolside relaxation, and indulgent spa therapies near the caldera.
€207
includes taxes & fees
9 Oct - 10 Oct
Enarma Suites & Spa Wellness Retreat
A balcony with a view of a city at night, a bench, a table with a bottle and glass, and a lit lantern.
A modern outdoor seating area with a glass-top table and a glass of white wine, overlooking a cityscape and a sunset.
A room with a wooden table, a bottle of wine, and a glass of wine. There is a bowl of tomatoes on the table.
A room with a view of a pool and trees, a bed with a pink bedspread, and a window with a curtain.

3. Aspronisi Luxury Villa

Aspronisi Luxury Villa
Santorini
€162
includes taxes & fees
18 Oct - 19 Oct
Aspronisi Luxury Villa
A rooftop terrace with two hot tubs, a seating area, and a view of the sea at night.
A kitchen with a wooden countertop, a sink, and a backsplash with intricate tile patterns. There are shelves above the countertop holding various items.
A room with a bed, a dining table with chairs, a TV, and a window with curtains.
A bedroom with a bed, a bedside table, and a view of the sea.

4. Caldera's Dolphin Suites

Caldera's Dolphin Suites
Santorini
€130
includes taxes & fees
30 Oct - 31 Oct
Caldera's Dolphin Suites
A view from a bathtub to a sunset over water, with a clear sky and distant land.
A bedroom with a bed, a wicker chair, a small table with a vase, a television on a stand, and a view of the sea through an open door.
A sun lounger with a view of the ocean and a boat in the distance.
A wooden four-poster bed with white curtains, positioned on a balcony overlooking a coastal landscape with mountains and the sea.

5. Celestia Grand

Celestia Grand
Santorini
€465
includes taxes & fees
1 Nov - 2 Nov
Celestia Grand
An aerial view of a resort with multiple swimming pools, a desert landscape, and a city in the background.
An indoor pool with a circular shape, surrounded by stone walls and candles.
A modern hotel room with a large bed, a flat-screen TV, a dining area with a table and chairs, and a balcony with a view of the landscape.
A bedroom with a large bed, a view of the sea through an open door, a round mirror, and a small table with decorative items.

6. North Santorini - A Luxury Spa Hotel

North Santorini - A Luxury Spa Hotel
Santorini
€463
includes taxes & fees
7 Oct - 8 Oct
North Santorini - A Luxury Spa Hotel
A resort with a pool, white buildings, and a view of the sea at sunset.
A modern bathroom with a glass shower enclosure, a vanity with a mirror, and a towel rack.
A modern living room with a white sofa, a round table, and two windows offering a view of the sea.
A sunset view from a rooftop terrace with tables and chairs, overlooking a calm sea and rocky coastline.

7. Grace Hotel, Auberge Collection

Grace Hotel, Auberge Collection
Santorini
  • Seaside luxury meets winery charm at this Santorini hotel offering spa treatments and ocean views.
€650
includes taxes & fees
26 Oct - 27 Oct
Grace Hotel, Auberge Collection
A modern, minimalist indoor pool area with a clear view of the ocean and a white outdoor seating area.
A woman sitting on a white balcony with a view of the sea and pink flowers.
A bedroom with a large bed, a bedside table with a book, a window with a view of the sea, and an open door leading to a balcony.
A modern room with a large window, a sofa, a small table, and a radiator.

8. Canaves Ena - Small Luxury Hotels of the World

Canaves Ena - Small Luxury Hotels of the World
Santorini
  • Beachfront sophistication awaits in this Santorini luxury hotel offering caldera views and poolside bliss.
€479
includes taxes & fees
1 Nov - 2 Nov
Canaves Ena - Small Luxury Hotels of the World
A sunset view from a balcony with white furniture, a stone wall, and a view of a coastal town.
A person reclining on a white chair with a view of the sea and a mountain in the background.
A pool area with a view of the sea and mountains.
A bedroom with a bed, a desk, a chair, a cabinet, and a view of the sea.

9. Katikies Santorini – Gea House – The Leading Hotels of the World

Katikies Santorini – Gea House – The Leading Hotels of the World
Santorini
  • Cliffside luxury and wellness indulgence awaits at this Santorini hotel with ocean-view dining, spa treatments, and poolside relaxation.
€474
includes taxes & fees
25 Oct - 26 Oct
Katikies Santorini – Gea House – The Leading Hotels of the World
An infinity pool with a view of the sea and distant islands.
A balcony with a table, a chair, and a white umbrella overlooking a coastal view with a boat on the water and buildings on the cliff.
A spacious room with a large window offering a view of the sea and mountains. There is a dining table with chairs, a white sofa, and a wooden cabinet.
A room with a wooden floor, white walls, and a view of the sea through open doors. There is a white chair, a small round table with apples, and a potted plant.

10. Katikies Santorini – Pelagos House - The Leading Hotels of the World

Katikies Santorini – Pelagos House - The Leading Hotels of the World
Santorini
  • Cliffside serenity meets island elegance at this Santorini retreat with 3 sparkling pools and spa indulgences.
€478
includes taxes & fees
25 Oct - 26 Oct
Katikies Santorini – Pelagos House - The Leading Hotels of the World
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Top Megalochori Hotel Reviews

Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

10/10 Excellent
"It’s a beautiful place. I loved my hot tub with a fabulous view. Had everything we needed for a fabulous stay. We will be back again soon."
Oluyemisi 3-night trip
Posted 6 hours ago
Santo Pure Oia Suites & Villas
Caldera Premium Villas - Adults Only

Caldera Premium Villas - Adults Only

10/10 Excellent
"Beautiful views, great rooms. Amazing breakfast and a lovely women serving us!"
Danielle 2-night trip
Posted 1 day ago
Caldera Premium Villas - Adults Only
White Pearl Villas

White Pearl Villas

10/10 Excellent
"Amazing that it’s AMAZING"
Jonathan 5-night trip
Posted 5 days ago
White Pearl Villas
Volcano View Hotel Santorini

Volcano View Hotel Santorini

10/10 Excellent
"Beautiful property with spectacular Caldera views. A number of restaurants nearby. Great staff."
Mark 2-night trip
Posted 9 days ago
Volcano View Hotel Santorini

Frequently asked questions

Are you looking for a luxury hotel for your Megalochori holiday?
Fly into Thira (JTR-Santorini National) Airport and then pamper yourself by staying at one of 5 Megalochori luxury hotels. Megalochori has some interesting things to see and do including Santorini Caldera and Gavalas Vineyard, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Megalochori?
May Seven Santorini is a luxury guest house with a full-service spa and a seasonal outdoor pool, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Vedema, a Luxury Collection Resort, Santorini and Enarma Suites & Spa Wellness Retreat are two other upscale options for your trip.
How many luxury hotels are there in Megalochori?
Lie in the lap of luxury during your getaway to Megalochori in one of Expedia's 5 luxury hotels.
When can I expect good weather in Megalochori?
Planning for the weather is a good way to make your trip to Megalochori relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 24°C, while the coldest months are January and February, with an average of 15°C. Average annual precipitation for Megalochori is 333 mm.
What's there to see and do in Megalochori?
Enjoy all that Megalochori has to offer and visit Santorini Caldera, Gavalas Vineyard and Boutari Winery. If you have a bit of extra time while you're in the area, you might want to check out Athinios Port and Venetsanos Winery.