Mesopotamia Holidays

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Things to do in Mesopotamia

In Mesopotamia, Argentina, visitors can indulge in birdwatching, hiking, and wildlife encounters. Don't miss the opportunity to embark on a Mesopotamia tour, where you can discover the ancient heritage of the area and explore various rituals. Engage in a cultural tour and immerse yourself in the vibrant festive processions that showcase local traditions. This destination offers a unique blend of natural beauty and rich cultural experiences for all travellers.

Shopping

In Mesopotamia, explore the vibrant shopping scene at Shopping del Sol for a range of local crafts and fashion. Don’t miss the bustling Feria de los Artesanos, where you’ll discover unique handmade souvenirs that truly reflect Argentine culture.

Recreation

Explore the tranquil surroundings at Termas de Río Hondo, where you can indulge in thermal baths and rejuvenating spa treatments. For relaxation, join yoga sessions amidst nature, or partake in guided meditation to enhance your wellness experience in this serene setting.

Adventure

Experience the stunning Ibera Wetlands with guided boat tours, spot wildlife while kayaking in the Paraná River, and trek through the lush Misiones rainforest to witness magnificent waterfalls. For thrill-seekers, zip-line through the canopy or join an exhilarating ATV ride across the diverse landscapes of Mesopotamia.

Nightlife

Experience the vibrant nightlife in Mesopotamia, Argentina, by visiting La Casona for live music and a lively atmosphere. For a relaxed evening, enjoy a drink at El Barcito, known for its friendly vibes and local brews. Both venues promise a memorable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Mesopotamia

Mesopotamia, Argentina, offers a wealth of attractions for those seeking scenic beauty and outdoor adventures. Visitors can explore national parks and discover the rich history of ancient Mesopotamians and their numerous gods. Additionally, the area celebrates various festivals that highlight its cultural heritage, ensuring a captivating experience for all travellers. Whether you're an adventure seeker or a history enthusiast, Mesopotamia has something to enrich your journey.

  • Portal Carambola: Nestled 22.5km from Mesopotamia, this national park offers breathtaking scenery and exhilarating outdoor adventures, perfect for nature enthusiasts seeking an unforgettable experience amidst lush landscapes.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.700000000000003°C)Light RainSunnyModerately HighAverage
February77.7°F (25.4°C)Light RainMostly Sunny
March72.9°F (22.700000000000003°C)Light RainMostly SunnyModerately HighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageAverage
November72.3°F (22.4°C)Light RainSunnyModerately HighAverage
December77.0°F (25.0°C)Light RainSunnyAverageSlightly High

Tips to save on your trip to Mesopotamia

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling to Mesopotamia during the low season () for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Top hotels in Mesopotamia

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
The price is €120 per night from 27 Feb to 28 Feb
€120
27 Feb - 28 Feb
9.8/10 Exceptional! (21 reviews)
Fantastic stay. Room was immaculate and hotel staff were very friendly and helpful. Great pool and beds were super comfortable.

Reviewed on 6 Feb 2026

Marriott Corrientes Hotel
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

2.5 out of 5
115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
The price is €38 per night from 19 Feb to 20 Feb
€38
19 Feb - 20 Feb
7.6/10 Good! (70 reviews)
La limpieza de los cuartos necesita mejorar. También agregar servicios básicos como TV y teléfono en los cuartos

Reviewed on 12 Mar 2025

O2 Hotel Gualeguaychú
Turismo Hotel Casino

Turismo Hotel Casino

2.5 out of 5
650 Entre Ríos Corrientes Corrientes
Fully refundableReserve now, pay when you stay
The price is €95 per night from 1 Mar to 2 Mar
€95
1 Mar - 2 Mar
6/10 (2 reviews)
Boa infraestrutura, e localização!

Reviewed on 4 Feb 2026

Turismo Hotel Casino
See all 510 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Isla Cambacua Beach

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Isla Cambacua Beach

Frequently asked questions

Can I cancel my flight booking to Mesopotamia due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our Customer Service Portal. It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Mesopotamia that have flexible change policies?
Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia.
What are some of the general tips for travellers to Mesopotamia during the COVID-19 outbreak?
If it's your first time travelling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one:
  • Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening.
  • Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening.
  • Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Mesopotamia?
Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway.
How can I find cheap tickets to Mesopotamia?
One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal.
How much is a flight to Mesopotamia?
You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just .
What are the most popular airports to fly into in Mesopotamia?
Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month.
When is the cheapest time to fly to Mesopotamia?
Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Mesopotamia?
Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal.
Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples:
  • Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.
  • LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.