Mesopotamia Holidays

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Things to do in Mesopotamia

In Mesopotamia, Argentina, visitors can indulge in birdwatching, hiking, and wildlife encounters. Don't miss the opportunity to embark on a Mesopotamia tour, where you can discover the ancient heritage of the area and explore various rituals. Engage in a cultural tour and immerse yourself in the vibrant festive processions that showcase local traditions. This destination offers a unique blend of natural beauty and rich cultural experiences for all travellers.

Shopping

In Mesopotamia, explore the vibrant shopping scene at Shopping del Sol for a range of local crafts and fashion. Don’t miss the bustling Feria de los Artesanos, where you’ll discover unique handmade souvenirs that truly reflect Argentine culture.

Recreation

Explore the tranquil surroundings at Termas de Río Hondo, where you can indulge in thermal baths and rejuvenating spa treatments. For relaxation, join yoga sessions amidst nature, or partake in guided meditation to enhance your wellness experience in this serene setting.

Adventure

Experience the stunning Ibera Wetlands with guided boat tours, spot wildlife while kayaking in the Paraná River, and trek through the lush Misiones rainforest to witness magnificent waterfalls. For thrill-seekers, zip-line through the canopy or join an exhilarating ATV ride across the diverse landscapes of Mesopotamia.

Nightlife

Experience the vibrant nightlife in Mesopotamia, Argentina, by visiting La Casona for live music and a lively atmosphere. For a relaxed evening, enjoy a drink at El Barcito, known for its friendly vibes and local brews. Both venues promise a memorable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Mesopotamia

Mesopotamia, Argentina, offers a wealth of attractions for those seeking scenic beauty and outdoor adventures. Visitors can explore national parks and discover the rich history of ancient Mesopotamians and their numerous gods. Additionally, the area celebrates various festivals that highlight its cultural heritage, ensuring a captivating experience for all travellers. Whether you're an adventure seeker or a history enthusiast, Mesopotamia has something to enrich your journey.

  • Portal Carambola: Nestled 22.5km from Mesopotamia, this national park offers breathtaking scenery and exhilarating outdoor adventures, perfect for nature enthusiasts seeking an unforgettable experience amidst lush landscapes.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.700000000000003°C)Light RainSunnyModerately HighAverage
February77.7°F (25.4°C)Light RainMostly Sunny
March72.9°F (22.700000000000003°C)Light RainMostly SunnyModerately HighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageAverage
November72.3°F (22.4°C)Light RainSunnyModerately HighAverage
December77.0°F (25.0°C)Light RainSunnyAverageSlightly High

Tips to save on your trip to Mesopotamia

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling to Mesopotamia during the low season () for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Top hotels in Mesopotamia

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
The price is €111 per night from 24 Jul to 25 Jul
€111
24 Jul - 25 Jul
9.8/10 Exceptional! (39 reviews)
"Me da mucho gusto que Corrientes tenga un hotel de esta categoría. El personal es excelente, desde el front desk hasta las personas de mantenimiento. Cuando supieron que íbamos a casarnos nos enviaron una bandeja de refreshments con una hermosa tarjeta de felicitación. La presión y temperatura de ..."

Reviewed on 6 Jun 2026

Marriott Corrientes Hotel
Turismo Hotel Casino

Turismo Hotel Casino

2.5 out of 5
650 Entre Ríos Corrientes Corrientes
Fully refundableReserve now, pay when you stay
The price is €81 per night from 5 Jul to 6 Jul
€81
5 Jul - 6 Jul
9/10 Wonderful! (7 reviews)
"The best place to stay in Corrientes! Amazing views"

Reviewed on 7 Apr 2026

Turismo Hotel Casino
Costarenas Hotel & Spa

Costarenas Hotel & Spa

3.5 out of 5
12 de Abril y Quiros Colon Entre Rios
The price is €106 per night from 3 Jul to 4 Jul
€106
3 Jul - 4 Jul
8.8/10 Excellent! (64 reviews)
"Estaba todo muy lindo"

Reviewed on 8 Jun 2026

Costarenas Hotel & Spa
See all 525 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mesopotamia attractions

A large church with a prominent dome and two bell towers.

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
See properties

Frequently asked questions

How much does a Mesopotamia holiday package cost?
Maybe less than you might think — from only , actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia holiday package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travellers.
How far in advance should I book my Mesopotamia holiday?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travellers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including holiday rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia holiday package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia holiday package?
Don't worry if you're rethinking your Mesopotamia holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realise life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.