South America Holidays

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    Save up to €185 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Plan, book, and manage your trip all in one place

Top destinations in South America

Bank of Brazil Cultural Center featuring street scenes and heritage architecture as well as a large group of people
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Sao Paulo

Sao Paulo

Top hotels in South America

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
The price is €62 per night from 7 Aug to 8 Aug
€62
7 Aug - 8 Aug
7.8/10 Good! (404 reviews)
"Excellent location in downtown with best value and services. 10 minutes walk to shopping, theaters, restaurants, subway, and 1 block from main retail street (Av. Corrientes = 42nd St in NYC) for taking taxi."

Reviewed on 12 Mar 2023

Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (1,000 reviews)
"Very nice hotel and reasonably priced. Staff is quite friendly and responsive. Will stay there again."

Reviewed on 12 May 2025

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Regal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630, Buenos Aires, Capital Federal
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on 6 Mar 2018

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Concorde Hotel
See all 113,724 properties in South America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I travel to South America right now?
Find info about South America travel restrictions, quarantine policies and much more by going to our Covid-19 Travel Advisor.
If I'm not able to travel, can I cancel my South America holiday package?
Don't stress if you're rethinking your South America holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur a fee from your hotel, airline or car rental company. We totally understand life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.
When is the best time of year to visit South America?
Anytime is an excellent time of the year to take a break in South America, but generally you'll land the best deals in . Prices increase in , so expect to pay more for your flights and hotel. Love sightseeing but don't like lining up for attractions? Organise your South America escape for . Typically, it's a lot quieter than in .
What should I do on holiday in South America?
From exciting attractions to hidden treasures, there's lots to do in South America. To help you plan your time in this amazing location, here are some of the most sought-after tours and activities:


How far in advance should I book my South America holiday?
While not all airlines advertise tickets early, it's usually possible to start comparing international fares on Expedia up to 12 months in advance. This is the time when you'll bag some fantastic bargains. If you're booking late, there's a chance you could get lucky. Sometimes the lowest prices emerge only weeks before departure.
What should I know before booking a South America travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, bundle your flights, hotels and rental cars and save a pretty penny. Whatever your holiday goals are, you'll find a package to suit your budget.

Popular places to visit

Our Lady of Bom Despacho Church

You can learn about the history of Cuiabá when you stop by Our Lady of Bom Despacho Church. Discover the area's museums and cathedral.

Our Lady of Bom Despacho Church

Eurico Gaspar Dutra Stadium

Catch an event at Eurico Gaspar Dutra Stadium during your trip to Cuiabá. Amble around the area's riverfront or visit its cathedral.

Eurico Gaspar Dutra Stadium
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.