Search over 1,000,000 properties worldwide and 550 airlines worldwide
Search over a million flights, hotels, packages, and more
No Expedia cancellation fee to change or cancel almost any hotel reservation
Visit South America to discover a diverse range of countries and terrain. From the salt flats of Bolivia, to the golden beaches of Brazil, to Argentina’s towering mountain ranges, adventure always awaits. Hike up active volcanos, cheer alongside passionate soccer fans at a national stadium and go swimming with the local marine life just offshore.
South America was home to influential ancient civilizations, whose legacy can still be felt today. Explore the fabled ruins of Machu Picchu in Peru and survey the monumental stone head statues on Easter Island.
The continent’s European colonial rulers have also left their mark. Spanish is spoken across much of the continent and Portuguese dominates in Brazil, though many tribes and indigenous people still speak their own native languages.
Make the city of Cuzco your base while exploring the Andes Mountains in Peru. See the floating reed islands of Lake Titicaca, which straddles Peru and Bolivia, or walk the colorful streets of lively Lima.
Ecuador offers enchanting colonial towns such as Quito, as well as rainforest treks through the Amazon. Journey offshore to Ecuador’s Galapagos Islands, where one-of-a-kind species, including giant tortoises and blue-footed boobies roam free.
Get a feel for Brazilian culture in Rio de Janeiro, a beachside city known for its street markets, love of soccer and fun-loving culture. Get in on the action with a match at Maracana Stadium.
For beautiful colonial architecture, head for Cartagena on Colombia’s northern coast.
At the southern tip of South America, Chile and Argentina are where you’ll find rolling vineyards and plenty of adventure sport opportunities. Whether you enjoy mountain biking, horseback riding or hiking, Patagonia is the place for you.
With plenty of international airports, South America is easier than ever to explore. Use local buses to get you from one place to another. Sign up for guided tours and treks to explore the continent efficiently and safely.
Whether you’re after rugged mountain interiors, sandy coastlines or remote islands, South America has everything you need for a memorable vacation.
Located in El Centro, this hotel is within 6 mi (10 km) of Galerias Pacifico, Obelisco and Teatro Colon. Florida Street and Casa Rosada are also within 6 mi (10 km).
Located in El Centro, this luxury hotel is within 6 mi (10 km) of Borges Cultural Center, Casa Rosada and Torre de los Ingleses. Teatro Colon is 1.1 mi (1.8 km) away.
Located in El Centro, this hotel is within 6 miles (10 km) of Lavalle Street, Plaza de Mayo and Teatro Colon. Obelisco and Florida Street are also within 6 miles (10 km).
Located in Santiago Center, this hotel is steps away from San Francisco Church, Municipal Theatre of Santiago and San Francisco Colonial Museum. University of Chile and Palacio de la Moneda are also within 6 miles (10 km).
Located in El Centro, this hotel is within 6 miles (10 km) of Lavalle Street, Obelisco and Teatro Colon. Plaza de Mayo and Florida Street are also within 6 miles (10 km).
Located in Santiago Center, this hotel is within 6 mi (10 km) of Pontifical Catholic University of Chile, Lastarria Shopping District and Santa Lucia Hill. National Archive and San Francisco Church are also within 6 mi (10 km).
Located in El Centro, this hotel is 0.6 mi (1 km) from Buenos Aires Metropolitan Cathedral, and within 6 mi (10 km) of Obelisco and Teatro Colon. Plaza de Mayo and Galerias Pacifico are also within 6 mi (10 km). July 9 Station and C. Pellegrini Station are within a 5-minute walk.
Located in Santiago Center, this aparthotel is within 6 miles (10 km) of Plaza de Armas, Palacio de la Moneda and University of Chile. O'Higgins Park and National Stadium are also within 6 miles (10 km).