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About South America
Expedia offers flights to South America to meet every traveller's needs. Whatever your flight need - Expedia has the flight for you. So choose from flights to South America or destinations around the world and discover how easy it is to make your flight reservations on Expedia.
More to explore for South America
Heading to South America? Explore South America with Expedia's Travel Guides to find the best hotels, city breaks, car hire deals and more!
Top South America Hotels
- Rochester Classic
- Regal Pacific Buenos Aires
- Hotel Concorde
- Galerías Hotel
- Argentina Tango Hotel
- Mercure Santiago Centro
- Globales Republica
- Departamentos Amoblados Torre Tagle
- Hilton Buenos Aires
- Lennox Hotel Buenos Aires
- Sheraton Libertador Hotel
- Windsor Asturias Hotel
- Amérian Buenos Aires Park Hotel
- InterContinental São Paulo
- Melia Paulista
- NH Buenos Aires Tango
- Reconquista Plaza
- El Conquistador Hotel
- Dazzler by Wyndham Buenos Aires San Martin
- Aeroporto Othon
Top Flight Destinations In World
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Top Flight Destinations In South America
- Flights to Sao Paulo
- Flights to Cartagena
- Flights to Buenos Aires
- Flights to Itajai
- Flights to Lima
- Flights to Florianopolis
- Flights to Bogota
- Flights to Santiago
- Flights to San Andres
- Flights to Medellin
- Flights to Quito
- Flights to Natal
- Flights to Salvador
- Flights to Costa Rica
- Flights to Ilheus-Itacare
- Flights to Fernando de Noronha
- Flights to Caldas Novas
- Flights to Vitoria
- Flights to Fortaleza
- Flights to Cali
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