San Diego Hotel Guide. Hotels in Mission Bay, San Diego, United States of America

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Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Mission Bay hotels

Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1570)
"Loved our stay "
United States
Jeremy
The price is €159
includes taxes & fees
18 Dec - 19 Dec
Hyatt Regency Mission Bay Spa and Marina
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is €154
includes taxes & fees
14 Dec - 15 Dec
San Diego Mission Bay Resort
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2351)
"Great stay, top tier service and excellent customer care "
Canada
Meriem
The price is €172
includes taxes & fees
15 Dec - 16 Dec
Paradise Point Resort & Spa
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (3916)
"The room was spotless the bed was so comfy the Amenities were great!! The food at the restaurant very delish"
United States
Emily
The price is €153
includes taxes & fees
14 Dec - 15 Dec
The Dana on Mission Bay
Outdoor pool, pool loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Marina District, 10 km from Mission Bay
8.6 out of 10, Excellent, (1857)
"Enjoyed my stay"
United States
Brandon
The price is €143
includes taxes & fees
20 Dec - 21 Dec
Hilton San Diego Bayfront
Room, 1 King Bed with Sofa bed, Marina View | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
6 km from Mission Bay
8.2 out of 10, Very good, (3176)
"Great stay! "
United States
Melissa
The price is €123
includes taxes & fees
3 Jan - 4 Jan 2026
Sheraton San Diego Resort
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 9.4 km from Mission Bay
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is €104
includes taxes & fees
28 Dec - 29 Dec
Staypineapple, Hotel Z, Gaslamp San Diego
Standard Room, 1 King Bed, Non Smoking, Bay View
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
8.2 km from Mission Bay
8.8 out of 10, Excellent, (727)
"Great little boutique hotel ! Friendly staff as well"
Canada
Caroll
The price is €97
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection
Exterior
Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 4 km from Mission Bay
8.2 out of 10, Very good, (1914)
"Efficient check in, clean rooms and great breakfast."
Canada
Wendy
The price is €79
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn San Diego Old Town
Reception
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
4.9 km from Mission Bay
8.8 out of 10, Excellent, (3568)
"Room was very clean, and the breakfast was good"
United States
Roxana
The price is €73
includes taxes & fees
17 Dec - 18 Dec
Kings Inn San Diego
Lobby
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
2.6 km from Mission Bay
7.4 out of 10, Good, (4110)
"Clean rooms and friendly staff."
United States
Aniket
The price is €83
includes taxes & fees
21 Dec - 22 Dec
Wyndham Garden San Diego Near SeaWorld
Courtyard
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 17.8 km from Mission Bay
8.4 out of 10, Very good, (1873)
"The room had a great view of the pool and staff was very friendly! "
United States
eva
The price is €96
includes taxes & fees
21 Dec - 22 Dec
DoubleTree by Hilton San Diego - Del Mar
Lobby
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach, 2.9 km from Mission Bay
9.0 out of 10, Wonderful, (800)
"good place to stay"
United States
Sisi
The price is €97
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott San Diego Pacific Beach
Exterior
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 9 km from Mission Bay
9.0 out of 10, Wonderful, (2871)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is €220
includes taxes & fees
13 Dec - 14 Dec
Manchester Grand Hyatt San Diego
Standard Room, 2 Queen Beds
GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 3 km from Mission Bay
8.0 out of 10, Very good, (1856)
"Courteous staff and clean room. "
United States
Rachel
The price is €86
includes taxes & fees
16 Dec - 17 Dec
GreenTree Inn San Diego Mission Bay
Terrace/patio
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
4.3 km from Mission Bay
8.8 out of 10, Excellent, (1279)
"Room was clean,buffet bkfast was good,staff were friendly & helpful!"
United States
Barry
The price is €96
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn San Diego/Mission Valley
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
8 km from Mission Bay
8.4 out of 10, Very good, (6052)
"Always an amazing stay"
United States
Jana
The price is €158
includes taxes & fees
14 Dec - 15 Dec
Wyndham San Diego Bayside
Front of property
Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista
2.0 star property
19.4 km from Mission Bay
7.2 out of 10, Good, (1984)
"Great stay"
United States
Eleazar
The price is €60
includes taxes & fees
14 Dec - 15 Dec
Hotel Palmeras Chula Vista
Reception
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
7 km from Mission Bay
8.8 out of 10, Excellent, (1554)
"Every time i have stayed here everything is always clean...no complaints!"
United States
Joseline
The price is €112
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Island Palms Hotel & Marina
Hot springs
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo
3.0 star property
5 km from Mission Bay
8.0 out of 10, Very good, (1817)
"Clean and helpful staff, thank you !"
United States
Bora
The Atwood Hotel San Diego - SeaWorld/Zoo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a city, signage and a bar

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Pacific Beach featuring a beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park which includes rides and a garden

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Mission Bay Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"yes "
Sandra 1-night trip
Posted 21 hours ago
Wyndham San Diego Bayside

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Frequently asked questions

What is Mission Bay like?
You'll be sure to have fun exploring San Diego's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighbourhood.
What's a favourite hotel to stay in Mission Bay?
Based on Expedia customer reviews, Paradise Point Resort & Spa is the highest ranked property in Mission Bay. This resort offers a marina and 5 outdoor pools. Other favourite options in the area include San Diego Mission Bay Resort and The Dana on Mission Bay.
How many hotels should I expect to find in the Mission Bay area?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals in Mission Bay.
What is there to do around this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission and Pacific Beaches, Ski Beach and Crown Point Shores while you're in Mission Bay. You could also plan a visit to Mission Bay or Mission Bay Golf Course while you're in the neighbourhood. Hotel Circle, North Cove Beach and Bahia Point Beach are just a few of the places to visit in and around Mission Bay. When you're sightseeing in San Diego, Bay City Brewing Co. and Sail Bay are also worth a stop.