Hotel Guide - Mississippi River hotels in , United States of America.

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
21 Jul - 22 Jul
Tomorrow
22 Jul - 23 Jul
This weekend
25 Jul - 27 Jul
Next weekend
1 Aug - 3 Aug

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near Mississippi River

The Eagles Nest Inn
Interior

The Eagles Nest Inn

3.0 star property
9.2 out of 10, Wonderful, (7)
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."
The price is €97
includes taxes & fees
23 Jul - 24 Jul
The Eagles Nest Inn
River's Edge Motel
Balcony

River's Edge Motel

2.0 star property
9.0 out of 10, Wonderful, (332)
"Great clean place to stay with friendly staff"
The price is €78
includes taxes & fees
22 Jul - 23 Jul
River's Edge Motel
Riverside Inn Hannibal
55-inch TV with cable channels, Netflix, Hulu

Riverside Inn Hannibal

2.5 star property
9.4 out of 10, Exceptional, (126)
"Excellent service, room, and location."
The price is €165
includes taxes & fees
29 Jul - 30 Jul
Riverside Inn Hannibal
Lighthouse Inn & Suites
Deluxe Room

Lighthouse Inn & Suites

4.0 star property
9.0 out of 10, Wonderful, (11)
"Location is excellent! Close to historic downtown but far enough away to be quiet and peaceful! Very clean and decor is wonderful!"
The price is €163
includes taxes & fees
22 Jul - 23 Jul
Lighthouse Inn & Suites
Sleep Inn & Suites
Exterior

Sleep Inn & Suites

2.5 star property
9.6 out of 10, Exceptional, (1004)
"Great stay!"
The price is €116
includes taxes & fees
17 Aug - 18 Aug
Sleep Inn & Suites
Garden House Bed and Breakfast
Front of property

Garden House Bed and Breakfast

2.0 star property
8.6 out of 10, Excellent, (22)
"A beautiful 19th century mansion, decorated in period. Quiet and comfortable."
The price is €100
includes taxes & fees
12 Aug - 13 Aug
Garden House Bed and Breakfast
Best Western On The River
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Best Western On The River

2.5 star property
8.6 out of 10, Excellent, (1005)
"Excellent and friendly staff!! Good breakfast as well!"
The price is €125
includes taxes & fees
24 Jul - 25 Jul
Best Western On The River
Motel 6 Hannibal, MO
Lobby sitting area

Motel 6 Hannibal, MO

2.0 star property
7.6 out of 10, Good, (1002)
"Large room's and very nice staff."
The price is €54
includes taxes & fees
27 Jul - 28 Jul
Motel 6 Hannibal, MO
Comfort Inn & Suites - Hannibal
Indoor pool, pool loungers

Comfort Inn & Suites - Hannibal

2.5 star property
7.6 out of 10, Good, (612)
"close to local attractions "
The price is €108
includes taxes & fees
17 Aug - 18 Aug
Comfort Inn & Suites - Hannibal
Quality Inn & Suites Hannibal
Lobby

Quality Inn & Suites Hannibal

2.5 star property
7.8 out of 10, Good, (1003)
"Good location, very welcoming, room was comfortable & breakfast was tasty. "
The price is €115
includes taxes & fees
28 Jul - 29 Jul
Quality Inn & Suites Hannibal
Super 8 by Wyndham Hannibal
Exterior

Super 8 by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (1003)
"Nice place, easy to find. "
The price is €66
includes taxes & fees
29 Jul - 30 Jul
Super 8 by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
Lobby sitting area

Howard Johnson BY Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (124)
"Old-style looks clean "
The price is €64
includes taxes & fees
29 Jul - 30 Jul
Howard Johnson BY Wyndham Hannibal
Days Inn by Wyndham Hannibal
Room, 2 Queen Beds, Non Smoking

Days Inn by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (177)
"Just needed for one night and it was ok staying there. Bed fairly good and good water pressure "
The price is €71
includes taxes & fees
1 Aug - 2 Aug
Days Inn by Wyndham Hannibal
Town & Country Inn and Suites
Classic Room, 2 Queen Beds, Non Smoking

Town & Country Inn and Suites

2.5 star property
9.2 out of 10, Wonderful, (843)
"Very friendly staff"
The price is €130
includes taxes & fees
27 Jul - 28 Jul
Town & Country Inn and Suites
Baymont by Wyndham Hannibal
Desk, laptop workspace, iron/ironing board, free WiFi

Baymont by Wyndham Hannibal

2.5 star property
6.2 out of 10, (675)
"Very good breakfast, nice heated indoor pool, good exercise room, friendly staff. Highly recommended."
The price is €68
includes taxes & fees
22 Jul - 23 Jul
Baymont by Wyndham Hannibal
Stoney Creek Inn Quincy
Indoor spa tub

Stoney Creek Inn Quincy

2.0 star property
8.8 out of 10, Excellent, (1006)
"Great stay at a great price"
Stoney Creek Inn Quincy
Fairfield Inn & Suites Quincy
Lobby

Fairfield Inn & Suites Quincy

2.5 star property
8.6 out of 10, Excellent, (324)
"Breakfast options were numerous, Room clean and staff were pleasant and helpful. "
The price is €116
includes taxes & fees
27 Jul - 28 Jul
Fairfield Inn & Suites Quincy
Heritage Hotel Quincy
Family Suite, Multiple Beds

Heritage Hotel Quincy

2.0 star property
8.8 out of 10, Excellent, (124)
"Renovated hotel, clean, nice staff. "
The price is €87
includes taxes & fees
29 Jul - 30 Jul
Heritage Hotel Quincy
Quality Inn & Suites Quincy - Downtown
Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi

Quality Inn & Suites Quincy - Downtown

2.5 star property
8.8 out of 10, Excellent, (428)
"Good experience but bed too firm."
The price is €117
includes taxes & fees
20 Aug - 21 Aug
Quality Inn & Suites Quincy - Downtown
The Atrium Hotel on Third
Lobby lounge

The Atrium Hotel on Third

3.5 star property
8.4 out of 10, Very good, (716)
"The hotel was quiet, bed was comfortable, and room was clean. There wasn't a lot of options for breakfast and no hot food was offered."
The price is €93
includes taxes & fees
4 Aug - 5 Aug
The Atrium Hotel on Third
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mississippi River Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Great place to stay and staff are nice, kind, and helpful. "
Jerre Mae 4-night trip
Posted 19 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Frequently asked questions

What's the area like around Mississippi River?

Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.

What's the best hotel to stay close to Mississippi River?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Clayton Plaza Hotel & Extended Stay and Drury Plaza Hotel St. Louis at the Arch.

If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.