Hotel Guide - Mississippi River hotels in , United States of America.

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Our top choices for Mississippi River hotels

1. River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (365 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is €78
includes taxes & fees
9 Jun - 10 Jun
River's Edge Motel

2. The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (25 reviews)
"Very nice place to stay loved the brick walls and wood floors leading up to the rooms"
United States
Gary
The price is €93
includes taxes & fees
6 Jun - 7 Jun
The Eagles Nest Inn

3. Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (769 reviews)
"The staff were very friendly and helpful, The breakfast was probably the best we had experienced at any hotel where we have stayed. If we pass through the area again, we will likely choose to stay there again."
United States
Carol
The price is €63
includes taxes & fees
10 Jun - 11 Jun
Baymont by Wyndham Hannibal

4. Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,000 reviews)
"Clean rooms, decent breakfast"
United States
Christina
The price is €110
includes taxes & fees
28 Jun - 29 Jun
Best Western On The River

5. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (175 reviews)
"Beautiful room and great location. Walkable to the river front and the shops downtown."
United States
Jana
The price is €190
includes taxes & fees
7 Jun - 8 Jun
Riverside Inn Hannibal

6. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
"Good breakfast"
United States
Neah
The price is €116
includes taxes & fees
21 Jun - 22 Jun
Sleep Inn & Suites Hannibal West

7. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
9.0 out of 10, Wonderful, (29 reviews)
"Fun themed rooms."
United States
Kelly
The price is €178
includes taxes & fees
4 Jun - 5 Jun
Lighthouse Inn & Suites

8. Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (542 reviews)
"Room was clean but basic"
United States
James
The price is €68
includes taxes & fees
11 Jun - 12 Jun
Economy Inn Wentzville

9. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,004 reviews)
"Nice staff, good parking, clean room."
United States
Susan
The price is €54
includes taxes & fees
14 Jun - 15 Jun
Motel 6 Hannibal, MO

10. Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,002 reviews)
"Property is most definitely dated. Linens were clean and comfortable for a night."
United States
Ashley
The price is €71
includes taxes & fees
21 Jun - 22 Jun
Super 8 by Wyndham O'Fallon MO/St. Louis Area

11. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (695 reviews)
"Beds comfortable- nice breakfast choices. A pleasant peaceful setting "
United States
Wanda J
The price is €103
includes taxes & fees
11 Jun - 12 Jun
Comfort Inn & Suites - Hannibal

12. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (249 reviews)
"A good place to stay in Hannibal."
United States
Marcia
The price is €67
includes taxes & fees
28 Jun - 29 Jun
Days Inn by Wyndham Hannibal

13. Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (168 reviews)
"The room was clean . The staff was helpful on things to do in the area. It was a very relaxing and the town was beautiful"
United States
Samantha
The price is €62
includes taxes & fees
7 Jun - 8 Jun
Howard Johnson BY Wyndham Hannibal

14. Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (517 reviews)
"I would book this same hotel again . It’s older, but very accommodating. "
United States
Michael
The price is €71
includes taxes & fees
7 Jun - 8 Jun
Baymont by Wyndham Keokuk

15. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,002 reviews)
"This place was perfect close to everything and all the amenities that you need"
United States
Sandra
The price is €80
includes taxes & fees
14 Jun - 15 Jun
Quality Inn & Suites Hannibal West

16. LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (49 reviews)
"The room was clean, furniture was relatively new, fresh paint and cozy."
United States
Sheila
The price is €66
includes taxes & fees
7 Jun - 8 Jun
LAKEVIEWINN

17. La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,004 reviews)
"Great stay"
United States
Micaela
The price is €73
includes taxes & fees
14 Jun - 15 Jun
La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

18. Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (541 reviews)
"I enjoy my fligth"
United States
Eulogio
The price is €78
includes taxes & fees
3 Jul - 4 Jul
Sleep Inn Saint Charles North

19. Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
107.1 km from Mississippi River
6.6 out of 10, (909 reviews)
"Not a bad place"
United States
Robert
The price is €95
includes taxes & fees
21 Jun - 22 Jun
Extended Stay America Select Suites St Louis Earth City

20. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,002 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is €62
includes taxes & fees
15 Jun - 16 Jun
Super 8 by Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
365 reviews
View
Lunch and dinner served
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
25 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
769 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,000 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
175 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Hollywood Casino & Hotel St. Louis and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.