
Murphysboro Holidays
Photo by Southernmost Illinois Tourism Bureau
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Top hotels in Murphysboro

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
120 MUDDY MONSTER ROAD, Murphysboro, IL
Fully refundable
The price is €92 per night from 1 Sept to 2 Sept
€92
1 Sept - 2 Sept
includes taxes & fees
9.4/10 Exceptional! (471 reviews)
"We had to leave before breakfast was offered so that was disappointing. The area was nice and clean though and the rooms were spacious. We would stay here again."
Reviewed on 24 Aug 2025

The Lab! Come stay in our brand new space.
Murphysboro
The price is €180 per night from 31 Aug to 1 Sept
€180
31 Aug - 1 Sept
includes taxes & fees

Lakefront, dog-friendly cabin with covered porch & firepit - near wine tasting
Murphysboro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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