Nuevo Santiago Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €185 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Nuevo Santiago

Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is €85 per night from 20 Oct to 21 Oct
€85
20 Oct - 21 Oct
includes taxes & fees
8.8/10 Excellent! (530 reviews)
"Bit of humidity in the room"

Reviewed on 10 Oct 2025

Hotel Mykonos Panama
Hotel Galería

Hotel Galería

3 out of 5
Vía Interamericana Santiago, Km 232.88, Nuevo Santiago
Fully refundableReserve now, pay when you stay
The price is €61 per night from 18 Oct to 19 Oct
€61
18 Oct - 19 Oct
includes taxes & fees
8.2/10 Very Good! (198 reviews)
Perfect overnight stop
"We stayed over night on our way home from Panama City. I used the pool, very clean and refreshing. Everything was clean and comfortable. I couldn’t get hot water in the shower, but my son had no problem. The breakfast was excellent."

Reviewed on 21 Jun 2025

Hotel Galería
Hotel Plaza

Hotel Plaza

3 out of 5
Interamericana, Nuevo Santiago, Veraguas
"It's a 35 $ a night hotel !!"

Reviewed on 21 Aug 2023

Hotel Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.