O Brien Hotels

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Check prices for these dates

Tonight
22 Nov - 23 Nov
Tomorrow
23 Nov - 24 Nov
Next weekend
28 Nov - 30 Nov
In two weeks
5 Dec - 7 Dec

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Top 10 trending O Brien hotels

Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
Alachua
9.4 out of 10, Exceptional, (1002)
"Great clean place to stay. "
United States
Mary
The price is €112
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Desk, blackout curtains, iron/ironing board, rollaway beds
Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

2.0 star property
Alachua
4.8 out of 10, (595)
"Staff was helpful and so courteous.."
United States
Christian
The price is €81
includes taxes & fees
6 Dec - 7 Dec
Americas Best Value Inn Alachua
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

2.5 star property
Alachua
9.4 out of 10, Exceptional, (466)
"Nice room only there for one night"
United States
Laryssa
The price is €102
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Alachua I-75
Exterior
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
Lake City
8.8 out of 10, Excellent, (1013)
"Excellent hotel. Spacious rooms, comfortable bed, great breakfast and friendly staff. Directly off I-75 for easy on and off. "
United States
Lisa
The price is €86
includes taxes & fees
2 Dec - 3 Dec
La Quinta Inn & Suite by Wyndham Lake City
Double Room, Non Smoking
High Springs Country Inn

High Springs Country Inn

2.0 star property
High Springs
8.6 out of 10, Excellent, (13)
"Great remodel of a retro motel."
United States
Kathleen
High Springs Country Inn
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1007)
"It was perfect, we got in super late an was met with a quick check in an a great breakfast the next day"
United States
Aurora
The price is €79
includes taxes & fees
2 Dec - 3 Dec
Best Western Plus Lake City
Property amenity
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

3.0 star property
Lake City
9.6 out of 10, Exceptional, (170)
"Nice place for a weekend trip to the springs close by.Would definitely stay here again."
United States
Mary
The price is €105
includes taxes & fees
7 Dec - 8 Dec
Courtyard By Marriott Lake City
Lobby
Comfort Suites Lake City

Comfort Suites Lake City

2.5 star property
Lake City
9.6 out of 10, Exceptional, (1003)
"We love to stop here when traveling to Orlando"
United States
Bridget
The price is €99
includes taxes & fees
7 Dec - 8 Dec
Comfort Suites Lake City
Standard Room, 2 Queen Beds, Non Smoking
Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee

2.5 star property
Live Oak
7.2 out of 10, Good, (604)
"Clean rooms, very friendly staff"
United States
Kristin L
The price is €65
includes taxes & fees
14 Dec - 15 Dec
Quality Inn White Springs Suwanee
Exterior
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1009)
"Clean room, easy check in and out, staff if very friendly and helpful"
United States
Row
The price is €106
includes taxes & fees
30 Nov - 1 Dec
Tru by Hilton Lake City
Outdoor pool, pool loungers
Quality Inn Lake City

Quality Inn Lake City

2.5 star property
Lake City
7.8 out of 10, Good, (946)
"Very nice place, would definitely stay there again!"
United States
Gerald
The price is €66
includes taxes & fees
21 Dec - 22 Dec
Quality Inn Lake City
Individually decorated, desk, laptop workspace, iron/ironing board
Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10

2.0 star property
Lake City
6.8 out of 10, (1002)
"Was quite and clean, a little dated but it was a good place to sleep they are pet friendly "
United States
William
The price is €63
includes taxes & fees
23 Nov - 24 Nov
Days Inn by Wyndham Lake City I-10
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

2.5 star property
Lake City
9.0 out of 10, Wonderful, (154)
"Clean property and nice staff"
United States
Thomas
The price is €96
includes taxes & fees
30 Nov - 1 Dec
Fairfield Inn & Suites Lake City
Outdoor pool
Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75

2.5 star property
Lake City
5.0 out of 10, (1001)
"Just a perfect place to take a break while traveling. Clean,comfortable and a great staff. "
United States
Cris
The price is €56
includes taxes & fees
1 Dec - 2 Dec
Baymont by Wyndham Lake City I-75
Standard Cabin, 1 Queen Bed | Exterior
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

2.0 star property
High Springs
9.8 out of 10, Exceptional, (139)
"Amazing getaway ,, I love the amenities and the firewood and everything was amazing great service perfect escape from reality."
United States
Emperesse
The price is €152
includes taxes & fees
1 Dec - 2 Dec
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
Lobby
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

2.0 star property
Lake City
8.4 out of 10, Very good, (45)
"Great little motel with extremely nice staff. "
United States
Georgiy
The price is €51
includes taxes & fees
30 Nov - 1 Dec
Motel 6 – Lake City, Fl – Medical Center
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

2.5 star property
Lake City
9.4 out of 10, Exceptional, (1001)
"It was a great stay "
United States
Miranda
The price is €88
includes taxes & fees
7 Dec - 8 Dec
Hampton Inn & Suites Lake City
BBQ/picnic Area
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2.0 star property
Lake City
8.8 out of 10, Excellent, (1004)
"Great value, super polite staff, and clean, comfortable rooms"
United States
chelsea
The price is €70
includes taxes & fees
23 Nov - 24 Nov
Americas Best Value Inn Lake City
Reception
BlueGem Motel

BlueGem Motel

2.0 star property
High Springs
9.2 out of 10, Wonderful, (383)
"Great place to stay."
United States
Wesley
BlueGem Motel
Pillow-top beds, in-room safe, desk, blackout curtains
Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75

2.0 star property
Lake City
7.4 out of 10, Good, (1001)
"We stay at this motel several times a year. It is always clean, the staff is always friendly and welcoming. We wouldn’t stay anywhere else."
United States
Troy
The price is €65
includes taxes & fees
1 Dec - 2 Dec
Days Inn by Wyndham Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

10/10 Excellent
"Great staff, huge room, quiet, clean, smoke free ! Best one of stayed at ! "
Craig 1-night trip
Posted 4 days ago
Motel 6 – Lake City, Fl – Medical Center

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.
What are some of the best holiday rentals that O Brien has to offer?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: This highly rated holiday home rental in O Brien is located on the beach, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. Our travellers also rate MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY as a favourite home for rent in O Brien. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool and complimentary high-speed (wired) Internet access. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 10 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Lafayette Blue Springs State Park and Lake City Mall in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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