A densely packed urban area with numerous buildings and a prominent tower on a hill.

Guayaquil Hotel Guide. Hotels in Puerto Santa Ana, Guayaquil, Ecuador

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Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

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Our top choices for Puerto Santa Ana hotels

2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,010 reviews)
"Beautiful, safe hotel. Staffing super friendly. Breakfast buffet very good."
United States
Karen
The price is €108
31 Jul - 1 Aug
Wyndham Guayaquil Puerto Santa Ana
Rooftop terrace

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (57 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is €78
19 Jul - 20 Jul
River View suites Puerto Santa Ana gye
Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (107 reviews)
"Lots of restaurants nearby"
Canada
kevin
The price is €76
17 Jul - 18 Jul
Luxury Suites Riverfront GYE
Outdoor pool, pool loungers

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (48 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is €109
16 Jul - 17 Jul
Iguanazu Bed & Breakfast
Terrace/patio

Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (122 reviews)
"Excellent customer service"
United States
Juan
The price is €346
19 Jul - 20 Jul
Hotel del Parque
Lobby

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 3.2 km from Puerto Santa Ana
8.8 out of 10, Excellent, (941 reviews)
"An excellent stay, good staff, clean room, and delicious food. I would stay there again without a doubt."
United States
MARTHA
The price is €99
26 Jul - 27 Jul
Hilton Colon Guayaquil
Lobby

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (111 reviews)
"Very nice, clean and the staff was super helpful in this hotel."
United States
Hidalgo
The price is €83
14 Aug - 15 Aug
Doubletree By Hilton Guayaquil
Children’s activities

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,000 reviews)
"Definitely the best and friendliest Hotel in Guayaquil!"
United States
Josef Walter
The price is €84
8 Aug - 9 Aug
Oro Verde Guayaquil
Café

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,009 reviews)
"Great overnight stay. Lovely staff, excellent room and amenities and a great breakfast!"
Australia
Peter
The price is €89
7 Aug - 8 Aug
Holiday Inn Guayaquil Airport by IHG
Living area

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
2.0 out of 10, (1 review)
"Deben haber un mejor desayuno, al menos frutas. No es tan bueno como parecía"
United States
Damariz
The price is €43
19 Jul - 20 Jul
NP Hotel & Suites
Lobby lounge

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (141 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is €58
22 Jul - 23 Jul
Mansión del Río
Daily buffet breakfast for a fee

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (668 reviews)
"Very nice place to stay ! "
United States
Diana
The price is €99
25 Jul - 26 Jul
Sheraton Guayaquil Hotel
Reception

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,004 reviews)
"Best place to stay, delicious food and the bed was a dream"
United States
Renata
The price is €89
26 Jul - 27 Jul
TRYP by Wyndham Guayaquil Airport
Rooftop bar, al fresco dining, open daily

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,000 reviews)
"The room was really clean and the staff in the lobby were really helpful. Breakfast was good"
United States
Rosa
The price is €83
18 Jul - 19 Jul
Wyndham Garden Guayaquil
Lobby

Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,001 reviews)
"Great locations and wonderful staff.!!"
Canada
Carlos
The price is €78
18 Jul - 19 Jul
Courtyard by Marriott Guayaquil
Property entrance

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (704 reviews)
"Good hotel"
United States
juan pablo
The price is €88
2 Aug - 3 Aug
Radisson Hotel Guayaquil
Terrace/patio

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 3.7 km from Puerto Santa Ana
8.6 out of 10, Excellent, (273 reviews)
"Very clean and comfortable rooms. The staff was very friendly and they're all fluent in English and Spanish. Breakfast in the restaurant was also delicious."
United States
Myna-Maria
The price is €61
19 Jul - 20 Jul
Hotel Puerto Pacifico Guayaquil Airport
Property entrance

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (643 reviews)
"Nice, clean simple, family run hotel with good transportation."
United States
Gerald
The price is €32
12 Aug - 13 Aug
DC Suites Aeropuerto
Outdoor pool, open 8:00 AM to 9:00 PM, pool loungers

Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Great place to stay"
United States
Martha Lucia
The price is €74
14 Aug - 15 Aug
Grand Hotel Guayaquil, Centro Histórico.
Terrace/patio

Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (57 reviews)
"Nice room, close to the airport. Was a bit noise at night because of the street dogs"
Australia
pavel
The price is €25
13 Aug - 14 Aug
Casa Serena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Chocolate Museum while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or World Trade Center.

Top Puerto Santa Ana Hotel Reviews

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

10/10 Excellent
"We are always staying at this hotel, for the good location, professional staff, good food, highly recommended"
MERY 1-night trip
Posted 1 hour ago
Unipark by Oro Verde Hotels

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 83 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.

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